Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PDCD2
  • Mouse genes Pdcd2
  • Rat genes Pdcd2
  • Zfish genes pdcd2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pdcd2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019899	enzyme binding	PDCD2	IPI	UniProtKB:Q96EB6	Human	PMID:23382074
Molecular Function	GO:0005515	protein binding	PDCD2	IPI	UniProtKB:O60260	Human	PMID:19146857
Molecular Function	GO:0005515	protein binding	PDCD2	IPI	UniProtKB:Q8IYX1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PDCD2	IPI	UniProtKB:P08574	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PDCD2	IPI	UniProtKB:P61981	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PDCD2	IPI	UniProtKB:Q15047-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PDCD2	IPI	UniProtKB:Q8TAP4-4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PDCD2	IPI	UniProtKB:Q92993	Human	PMID:32814053
Cellular Component	GO:0070062	extracellular exosome	PDCD2	HDA		Human	PMID:19056867
Cellular Component	GO:0005634	nucleus	Pdcd2	IDA		Rat	PMID:15942958|RGD:1598733
Biological Process	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	PDCD2	IDA		Human	PMID:20605493
Biological Process	GO:0030218	erythrocyte differentiation	pdcd2	IMP	ZFIN:ZDB-MRPHLNO-140106-3	Zfish	PMID:22800338
Biological Process	GO:0060218	hematopoietic stem cell differentiation	pdcd2	IMP	ZFIN:ZDB-MRPHLNO-140106-3	Zfish	PMID:22800338
Biological Process	GO:0043065	positive regulation of apoptotic process	PDCD2	IDA		Human	PMID:20605493
Biological Process	GO:1902035	positive regulation of hematopoietic stem cell proliferation	PDCD2	IMP		Human	PMID:22922207
Biological Process	GO:0012501	programmed cell death	Pdcd2	IEP		Rat	PMID:2072913|RGD:61688
Biological Process	GO:1901532	regulation of hematopoietic progenitor cell differentiation	PDCD2	IMP		Human	PMID:22922207
Biological Process	GO:0007088	regulation of mitotic nuclear division	pdcd2	IMP	ZFIN:ZDB-MRPHLNO-140106-3	Zfish	PMID:22800338

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern