Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PDE1B
  • Mouse genes Pde1b
  • Rat genes Pde1b
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pde1b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	PDE1B	IDA		Human	PMID:14687666
Molecular Function	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	PDE1B	IMP		Human	PMID:8855339
Molecular Function	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	Pde1b	IDA		Rat	PMID:1326532|RGD:633601
Molecular Function	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	PDE1B	IDA		Human	PMID:14687666
Molecular Function	GO:0004117	calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity	PDE1B	IDA		Human	PMID:9419816
Molecular Function	GO:0004112	cyclic-nucleotide phosphodiesterase activity	Pde1b	IDA		Rat	PMID:1326532|RGD:633601
Molecular Function	GO:0005515	protein binding	PDE1B	IPI	UniProtKB:Q9NUX5	Human	PMID:21044950
Cellular Component	GO:0005829	cytosol	PDE1B	IDA		Human	PMID:8855339
Cellular Component	GO:0043025	neuronal cell body	Pde1b	IDA		Rat	PMID:15305867|RGD:2312524
Biological Process	GO:0097011	cellular response to granulocyte macrophage colony-stimulating factor stimulus	PDE1B	IDA		Human	PMID:14687666
Biological Process	GO:0036006	cellular response to macrophage colony-stimulating factor stimulus	PDE1B	IDA		Human	PMID:14687666
Biological Process	GO:0007626	locomotory behavior	Pde1b	IMP	MGI:MGI:2676625	Mouse	PMID:12077213
Biological Process	GO:0007626	locomotory behavior	Pde1b	IMP	MGI:MGI:3604470	Mouse	PMID:17559891
Biological Process	GO:0030224	monocyte differentiation	PDE1B	IEP		Human	PMID:14687666
Biological Process	GO:0042053	regulation of dopamine metabolic process	Pde1b	IMP	MGI:MGI:3604470	Mouse	PMID:17559891
Biological Process	GO:0001505	regulation of neurotransmitter levels	Pde1b	IMP	MGI:MGI:3604470	Mouse	PMID:17559891
Biological Process	GO:0001975	response to amphetamine	Pde1b	IMP	MGI:MGI:2676625	Mouse	PMID:17010100
Biological Process	GO:0001975	response to amphetamine	Pde1b	IGI	MGI:MGI:94860	Mouse	PMID:17010100
Biological Process	GO:0001975	response to amphetamine	Pde1b	IMP	MGI:MGI:3604470	Mouse	PMID:17559891
Biological Process	GO:0042428	serotonin metabolic process	Pde1b	IMP	MGI:MGI:3604470	Mouse	PMID:17559891
Biological Process	GO:0007165	signal transduction	Pde1b	IMP	MGI:MGI:2676625	Mouse	PMID:12077213
Biological Process	GO:0008542	visual learning	Pde1b	IMP	MGI:MGI:2676625	Mouse	PMID:12077213
Biological Process	GO:0008542	visual learning	Pde1b	IGI	MGI:MGI:94860	Mouse	PMID:17010100

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern