Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PDK3
  • Mouse genes Pdk3
  • Rat genes Pdk3
  • Zfish genes pdk3a,pdk3b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pdk3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005524	ATP binding	PDK3	IDA		Human	PMID:15861126
Molecular Function	GO:0005515	protein binding	PDK3	IPI	UniProtKB:P10515	Human	PMID:15861126
Molecular Function	GO:0005515	protein binding	PDK3	IPI	UniProtKB:P10515	Human	PMID:17683942
Molecular Function	GO:0005515	protein binding	PDK3	IPI	UniProtKB:P10515	Human	PMID:28514442
Molecular Function	GO:0004672	protein kinase activity	PDK3	IDA		Human	PMID:15861126
Molecular Function	GO:0004674	protein serine/threonine kinase activity	PDK3	IDA		Human	PMID:11486000
Molecular Function	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity	PDK3	EXP		Human	PMID:11485553
Molecular Function	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity	PDK3	IDA		Human	PMID:11486000
Cellular Component	GO:0005739	mitochondrion	PDK3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	Pdk3	HDA		Mouse	PMID:14651853
Cellular Component	GO:0005739	mitochondrion	Pdk3	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005730	nucleolus	PDK3	IDA		Human	GO_REF:0000052
Biological Process	GO:0071398	cellular response to fatty acid	PDK3	IMP		Human	PMID:20715114
Biological Process	GO:0071333	cellular response to glucose stimulus	Pdk3	IMP		Rat	PMID:22809973|RGD:8553296
Biological Process	GO:0097411	hypoxia-inducible factor-1alpha signaling pathway	PDK3	IMP		Human	PMID:18718909
Biological Process	GO:0018105	peptidyl-serine phosphorylation	PDK3	IDA		Human	PMID:11486000
Biological Process	GO:0035357	peroxisome proliferator activated receptor signaling pathway	PDK3	IMP		Human	PMID:17669420
Biological Process	GO:0010510	regulation of acetyl-CoA biosynthetic process from pyruvate	PDK3	IMP		Human	PMID:22865452
Biological Process	GO:0010906	regulation of glucose metabolic process	PDK3	IMP		Human	PMID:22865452
Biological Process	GO:2000377	regulation of reactive oxygen species metabolic process	PDK3	IMP		Human	PMID:22865452

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern