Source |
Alliance of Genome Resources |
Category | ID | Classification term | Gene | Evidence | Inferred from | Organism | Reference |
---|---|---|---|---|---|---|---|
Molecular Function | GO:0004676 | 3-phosphoinositide-dependent protein kinase activity | PDPK1 | IDA | Human | PMID:9368760 | |
Molecular Function | GO:0004676 | 3-phosphoinositide-dependent protein kinase activity | Pdpk1 | IDA | Mouse | PMID:19047061 | |
Molecular Function | GO:0004676 | 3-phosphoinositide-dependent protein kinase activity | Pdpk1 | IMP | MGI:MGI:3795190 | Mouse | PMID:18347057 |
Molecular Function | GO:0004676 | 3-phosphoinositide-dependent protein kinase activity | Pdpk1 | IDA | Mouse | PMID:15116068 | |
Molecular Function | GO:0004676 | 3-phosphoinositide-dependent protein kinase activity | Pdpk1 | IMP | MGI:MGI:3043781 | Mouse | PMID:15116068 |
Molecular Function | GO:0004676 | 3-phosphoinositide-dependent protein kinase activity | Pdpk1 | IMP | MGI:MGI:3628819 | Mouse | PMID:16642023 |
Molecular Function | GO:0004676 | 3-phosphoinositide-dependent protein kinase activity | Pdpk1 | IDA | Mouse | PMID:10075713 | |
Molecular Function | GO:0004676 | 3-phosphoinositide-dependent protein kinase activity | Pdpk1 | IDA | Rat | PMID:14585963|RGD:1581775 | |
Molecular Function | GO:0004676 | 3-phosphoinositide-dependent protein kinase activity | Pdpk1 | IDA | Rat | PMID:16314505|RGD:1581774 | |
Molecular Function | GO:0005158 | insulin receptor binding | Pdpk1 | IDA | Rat | PMID:16314505|RGD:1581774 | |
Molecular Function | GO:0019209 | kinase activator activity | Pdpk1 | IDA | Mouse | PMID:19047061 | |
Molecular Function | GO:0019209 | kinase activator activity | Pdpk1 | IMP | MGI:MGI:3795190 | Mouse | PMID:18347057 |
Molecular Function | GO:0016004 | phospholipase activator activity | PDPK1 | IMP | Human | PMID:22454520 | |
Molecular Function | GO:0043274 | phospholipase binding | PDPK1 | IPI | UniProtKB:P19174 | Human | PMID:22454520 |
Molecular Function | GO:0005515 | protein binding | PDPK1 | IPI | UniProtKB:P31749 | Human | PMID:11438723 |
Molecular Function | GO:0005515 | protein binding | PDPK1 | IPI | UniProtKB:Q8WTW4 | Human | PMID:18616680 |
Molecular Function | GO:0005515 | protein binding | PDPK1 | IPI | UniProtKB:Q00005 | Human | PMID:21075311 |
Molecular Function | GO:0005515 | protein binding | PDPK1 | IPI | UniProtKB:P31749 | Human | PMID:21775285 |
Molecular Function | GO:0005515 | protein binding | PDPK1 | IPI | UniProtKB:P31749 | Human | PMID:23397142 |
Molecular Function | GO:0005515 | protein binding | PDPK1 | IPI | UniProtKB:P31749 | Human | PMID:26256536 |
Molecular Function | GO:0005515 | protein binding | PDPK1 | IPI | UniProtKB:O75385 | Human | PMID:26593251 |
Molecular Function | GO:0005515 | protein binding | Pdpk1 | IPI | PR:Q2VEB4 | Mouse | PMID:16337591 |
Molecular Function | GO:0030295 | protein kinase activator activity | Pdpk1 | IDA | Mouse | PMID:15116068 | |
Molecular Function | GO:0030295 | protein kinase activator activity | Pdpk1 | IMP | MGI:MGI:3043781 | Mouse | PMID:15116068 |
Molecular Function | GO:0030295 | protein kinase activator activity | Pdpk1 | IMP | MGI:MGI:3628819 | Mouse | PMID:16642023 |
Molecular Function | GO:0030295 | protein kinase activator activity | Pdpk1 | IDA | Mouse | PMID:10075713 | |
Molecular Function | GO:0019901 | protein kinase binding | Pdpk1 | IDA | Rat | PMID:14585963|RGD:1581775 | |
Molecular Function | GO:0004674 | protein serine/threonine kinase activity | PDPK1 | IDA | Human | PMID:9368760 | |
Cellular Component | GO:0042995 | cell projection | PDPK1 | IDA | Human | PMID:22454520 | |
Cellular Component | GO:0005737 | cytoplasm | PDPK1 | IDA | Human | PMID:9637919 | |
Cellular Component | GO:0005737 | cytoplasm | Pdpk1 | IDA | Mouse | PMID:12783890 | |
Cellular Component | GO:0031410 | cytoplasmic vesicle | Pdpk1 | IDA | Mouse | PMID:12783890 | |
Cellular Component | GO:0005829 | cytosol | PDPK1 | IDA | Human | GO_REF:0000052 | |
Cellular Component | GO:0005829 | cytosol | Pdpk1 | IDA | Rat | PMID:16314505|RGD:1581774 | |
Cellular Component | GO:0043204 | perikaryon | Pdpk1 | IDA | Rat | PMID:18971483|RGD:10449508 | |
Cellular Component | GO:0005886 | plasma membrane | PDPK1 | IDA | Human | PMID:14749367 | |
Cellular Component | GO:0005886 | plasma membrane | PDPK1 | IDA | Human | PMID:22454520 | |
Cellular Component | GO:0005886 | plasma membrane | PDPK1 | IDA | Human | PMID:9637919 | |
Cellular Component | GO:0005886 | plasma membrane | Pdpk1 | IDA | Rat | PMID:16314505|RGD:1581774 | |
Cellular Component | GO:0014069 | postsynaptic density | Pdpk1 | IDA | Mouse | PMID:17114649 | |
Biological Process | GO:0032148 | activation of protein kinase B activity | PDPK1 | IDA | Human | PMID:9368760 | |
Biological Process | GO:0019722 | calcium-mediated signaling | PDPK1 | IMP | Human | PMID:22454520 | |
Biological Process | GO:0016477 | cell migration | PDPK1 | IMP | Human | PMID:22454520 | |
Biological Process | GO:1990416 | cellular response to brain-derived neurotrophic factor stimulus | Pdpk1 | IEP | Rat | PMID:18971483|RGD:10449508 | |
Biological Process | GO:0071364 | cellular response to epidermal growth factor stimulus | PDPK1 | IMP | Human | PMID:22454520 | |
Biological Process | GO:0032869 | cellular response to insulin stimulus | PDPK1 | IMP | Human | PMID:10567711 | |
Biological Process | GO:0007173 | epidermal growth factor receptor signaling pathway | PDPK1 | IMP | Human | PMID:22454520 | |
Biological Process | GO:0097191 | extrinsic apoptotic signaling pathway | PDPK1 | IMP | Human | PMID:16207722 | |
Biological Process | GO:0048041 | focal adhesion assembly | Pdpk1 | IMP | Rat | PMID:14585963|RGD:1581775 | |
Biological Process | GO:0006972 | hyperosmotic response | Pdpk1 | IDA | Mouse | PMID:12783890 | |
Biological Process | GO:0008286 | insulin receptor signaling pathway | Pdpk1 | IMP | MGI:MGI:3795190 | Mouse | PMID:18347057 |
Biological Process | GO:0008286 | insulin receptor signaling pathway | Pdpk1 | IDA | Mouse | PMID:19047061 | |
Biological Process | GO:0048009 | insulin-like growth factor receptor signaling pathway | Pdpk1 | IMP | Mouse | PMID:33377210 | |
Biological Process | GO:0048009 | insulin-like growth factor receptor signaling pathway | Pdpk1 | IDA | Mouse | PMID:23472139 | |
Biological Process | GO:0048009 | insulin-like growth factor receptor signaling pathway | Pdpk1 | IDA | Mouse | PMID:33567274 | |
Biological Process | GO:0035556 | intracellular signal transduction | PDPK1 | IDA | Human | PMID:14749367 | |
Biological Process | GO:0010667 | negative regulation of cardiac muscle cell apoptotic process | Pdpk1 | IMP | Mouse | MGI:MGI:3849539|PMID:19429709 | |
Biological Process | GO:2000352 | negative regulation of endothelial cell apoptotic process | PDPK1 | IMP | Human | PMID:26235810 | |
Biological Process | GO:0043524 | negative regulation of neuron apoptotic process | Pdpk1 | IMP | Rat | PMID:18971483|RGD:10449508 | |
Biological Process | GO:0006469 | negative regulation of protein kinase activity | PDPK1 | IDA | Human | PMID:9373175 | |
Biological Process | GO:0034122 | negative regulation of toll-like receptor signaling pathway | Pdpk1 | IMP | Mouse | MGI:MGI:4821539|PMID:20584979 | |
Biological Process | GO:0030512 | negative regulation of transforming growth factor beta receptor signaling pathway | PDPK1 | IDA | Human | PMID:17327236 | |
Biological Process | GO:0018107 | peptidyl-threonine phosphorylation | PDPK1 | IDA | Human | PMID:9368760 | |
Biological Process | GO:0045766 | positive regulation of angiogenesis | PDPK1 | IMP | Human | PMID:23802567 | |
Biological Process | GO:0043536 | positive regulation of blood vessel endothelial cell migration | PDPK1 | IMP | Human | PMID:23802567 | |
Biological Process | GO:0010518 | positive regulation of phospholipase activity | PDPK1 | IMP | Human | PMID:22454520 | |
Biological Process | GO:1903078 | positive regulation of protein localization to plasma membrane | PDPK1 | IMP | Human | PMID:10567711 | |
Biological Process | GO:0051281 | positive regulation of release of sequestered calcium ion into cytosol | PDPK1 | IDA | Human | PMID:22454520 | |
Biological Process | GO:1903672 | positive regulation of sprouting angiogenesis | PDPK1 | IMP | Human | PMID:26235810 | |
Biological Process | GO:1905564 | positive regulation of vascular endothelial cell proliferation | PDPK1 | IMP | Human | PMID:23802567 | |
Biological Process | GO:0006468 | protein phosphorylation | PDPK1 | IDA | Human | PMID:14585963 | |
Biological Process | GO:0010594 | regulation of endothelial cell migration | Pdpk1 | IMP | Mouse | MGI:MGI:3789556|PMID:17371830 | |
Biological Process | GO:0043122 | regulation of I-kappaB kinase/NF-kappaB signaling | PDPK1 | IMP | Human | PMID:16207722 | |
Biological Process | GO:0043304 | regulation of mast cell degranulation | Pdpk1 | IMP | Mouse | MGI:MGI:5298334|PMID:21063107 | |
Biological Process | GO:0003323 | type B pancreatic cell development | Pdpk1 | IMP | Mouse | MGI:MGI:4365695|PMID:19635472 |
EXP Inferred from experiment |
IDA Inferred from direct assay |
IEP Inferred from expression pattern |
IGI Inferred from genetic interaction |
IMP Inferred from mutant phenotype |
IPI Inferred from physical interaction |
HTP Inferred from High Throughput Experiment |
HDA Inferred from High Throughput Direct Assay |
HMP Inferred from High Throughput Mutant Phenotype |
HGI Inferred from High Throughput Genetic Interaction |
HEP Inferred from High Throughput Expression Pattern |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/21/2024 MGI 6.24 |
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