Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PDXK
  • Mouse genes Pdxk
  • Rat genes Pdxk
  • Zfish genes pdxka,pdxkb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pdxk

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005524	ATP binding	PDXK	IDA		Human	PMID:16600635
Molecular Function	GO:0005524	ATP binding	PDXK	IDA		Human	PMID:17766369
Molecular Function	GO:0031403	lithium ion binding	PDXK	IDA		Human	PMID:9252787
Molecular Function	GO:0000287	magnesium ion binding	PDXK	IDA		Human	PMID:17766369
Molecular Function	GO:0097159	organic cyclic compound binding	Pdxk	IPI	CHEBI:45307	Rat	PMID:15975926|RGD:2303026
Molecular Function	GO:0030955	potassium ion binding	PDXK	IDA		Human	PMID:17766369
Molecular Function	GO:0030955	potassium ion binding	PDXK	IDA		Human	PMID:9252787
Molecular Function	GO:0042803	protein homodimerization activity	PDXK	IDA		Human	PMID:16600635
Molecular Function	GO:0042803	protein homodimerization activity	PDXK	IDA		Human	PMID:17766369
Molecular Function	GO:0070280	pyridoxal binding	Pdxk	IDA		Rat	PMID:6255956|RGD:2303024
Molecular Function	GO:0008478	pyridoxal kinase activity	PDXK	IDA		Human	PMID:10987144
Molecular Function	GO:0008478	pyridoxal kinase activity	PDXK	IDA		Human	PMID:17766369
Molecular Function	GO:0008478	pyridoxal kinase activity	PDXK	IMP		Human	PMID:31187503
Molecular Function	GO:0008478	pyridoxal kinase activity	PDXK	IDA		Human	PMID:9099727
Molecular Function	GO:0008478	pyridoxal kinase activity	Pdxk	IDA		Rat	PMID:2988502|RGD:2303018
Molecular Function	GO:0030170	pyridoxal phosphate binding	PDXK	IDA		Human	PMID:16600635
Molecular Function	GO:0036094	small molecule binding	Pdxk	IPI	CHEBI:45307	Rat	PMID:15975926|RGD:2303026
Molecular Function	GO:0031402	sodium ion binding	PDXK	IDA		Human	PMID:17766369
Molecular Function	GO:0031402	sodium ion binding	PDXK	IDA		Human	PMID:9252787
Molecular Function	GO:0008270	zinc ion binding	PDXK	IDA		Human	PMID:10987144
Cellular Component	GO:0005829	cytosol	PDXK	HDA		Human	PMID:16780588
Cellular Component	GO:0070062	extracellular exosome	PDXK	HDA		Human	PMID:19056867
Cellular Component	GO:0005654	nucleoplasm	PDXK	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	PDXK	HDA		Human	PMID:21630459
Biological Process	GO:0043066	negative regulation of apoptotic process	Pdxk	IMP		Rat	PMID:17115225|RGD:2303034
Biological Process	GO:0009443	pyridoxal 5'-phosphate salvage	PDXK	IDA		Human	PMID:10987144
Biological Process	GO:0009443	pyridoxal 5'-phosphate salvage	PDXK	IDA		Human	PMID:17766369
Biological Process	GO:0009443	pyridoxal 5'-phosphate salvage	PDXK	IMP		Human	PMID:31187503
Biological Process	GO:0009443	pyridoxal 5'-phosphate salvage	PDXK	IDA		Human	PMID:9099727
Biological Process	GO:0042823	pyridoxal phosphate biosynthetic process	Pdxk	IDA		Rat	PMID:2988502|RGD:2303018
Biological Process	GO:0014075	response to amine	Pdxk	IEP		Rat	PMID:17115225|RGD:2303034
Biological Process	GO:0032094	response to food	Pdxk	IEP		Rat	PMID:10204830|RGD:2303025
Biological Process	GO:0017085	response to insecticide	Pdxk	IEP		Rat	PMID:2119399|RGD:2303015
Biological Process	GO:0032570	response to progesterone	Pdxk	IEP		Rat	PMID:3681477|RGD:2303023
Biological Process	GO:0009636	response to toxic substance	Pdxk	IEP		Rat	PMID:3007703|RGD:2303019
Biological Process	GO:0010165	response to X-ray	Pdxk	IEP		Rat	PMID:2928487|RGD:2303016
Biological Process	GO:0009410	response to xenobiotic stimulus	Pdxk	IEP		Rat	PMID:212768|RGD:2303014

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern