Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PDXP
  • Mouse genes Pdxp
  • Rat genes Pdxp
  • Zfish genes pdxp
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pdxp

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019838	growth factor binding	Pdxp	IPI	RGD:3552	Rat	PMID:18929742|RGD:10044027
Molecular Function	GO:0031072	heat shock protein binding	PDXP	IDA		Human	PMID:19000834
Molecular Function	GO:0000287	magnesium ion binding	Pdxp	IDA		Mouse	MGI:MGI:5545856|PMID:24338687
Molecular Function	GO:0004721	phosphoprotein phosphatase activity	PDXP	IDA		Human	PMID:15580268
Molecular Function	GO:0004721	phosphoprotein phosphatase activity	PDXP	IDA		Human	PMID:19000834
Molecular Function	GO:0005515	protein binding	PDXP	IPI	UniProtKB:P29066	Human	PMID:17500066
Molecular Function	GO:0005515	protein binding	Pdxp	IPI	UniProtKB:P60487	Mouse	MGI:MGI:5545856|PMID:24338687
Molecular Function	GO:0042803	protein homodimerization activity	Pdxp	IDA		Mouse	MGI:MGI:6695679|PMID:25783190
Molecular Function	GO:0042803	protein homodimerization activity	Pdxp	IPI	UniProtKB:P60487	Mouse	MGI:MGI:5545856|PMID:24338687
Molecular Function	GO:0033883	pyridoxal phosphatase activity	PDXP	IDA		Human	PMID:14522954
Molecular Function	GO:0033883	pyridoxal phosphatase activity	PDXP	IDA		Human	PMID:8132548
Molecular Function	GO:0033883	pyridoxal phosphatase activity	Pdxp	IDA		Mouse	MGI:MGI:6695679|PMID:25783190
Molecular Function	GO:0033883	pyridoxal phosphatase activity	Pdxp	IDA		Mouse	MGI:MGI:5545857|PMID:24338473
Molecular Function	GO:0033883	pyridoxal phosphatase activity	Pdxp	IDA		Mouse	MGI:MGI:5545856|PMID:24338687
Cellular Component	GO:0015629	actin cytoskeleton	PDXP	IDA		Human	PMID:15580268
Cellular Component	GO:0005911	cell-cell junction	Pdxp	IDA		Mouse	PMID:23793062
Cellular Component	GO:0032154	cleavage furrow	PDXP	IDA		Human	PMID:15580268
Cellular Component	GO:0070938	contractile ring	PDXP	IDA		Human	PMID:15580268
Cellular Component	GO:0005829	cytosol	PDXP	IDA		Human	PMID:15580268
Cellular Component	GO:0030027	lamellipodium	PDXP	IDA		Human	PMID:15580268
Cellular Component	GO:0030496	midbody	PDXP	IDA		Human	PMID:15580268
Cellular Component	GO:0005886	plasma membrane	PDXP	IDA		Human	PMID:15580268
Cellular Component	GO:0032587	ruffle membrane	PDXP	IDA		Human	PMID:15580268
Biological Process	GO:0031247	actin rod assembly	PDXP	IDA		Human	PMID:19000834
Biological Process	GO:0031247	actin rod assembly	PDXP	IMP		Human	PMID:19000834
Biological Process	GO:0071318	cellular response to ATP	PDXP	IDA		Human	PMID:19000834
Biological Process	GO:0016311	dephosphorylation	PDXP	IDA		Human	PMID:14522954
Biological Process	GO:0016311	dephosphorylation	PDXP	IDA		Human	PMID:8132548
Biological Process	GO:0016311	dephosphorylation	Pdxp	IDA		Mouse	MGI:MGI:6695679|PMID:25783190
Biological Process	GO:0016311	dephosphorylation	Pdxp	IDA		Mouse	MGI:MGI:5545856|PMID:24338687
Biological Process	GO:0030836	positive regulation of actin filament depolymerization	PDXP	IMP		Human	PMID:15580268
Biological Process	GO:0006470	protein dephosphorylation	PDXP	IDA		Human	PMID:15580268
Biological Process	GO:0032361	pyridoxal phosphate catabolic process	PDXP	IDA		Human	PMID:14522954
Biological Process	GO:0032361	pyridoxal phosphate catabolic process	PDXP	IDA		Human	PMID:8132548
Biological Process	GO:0032361	pyridoxal phosphate catabolic process	Pdxp	IDA		Mouse	MGI:MGI:5545857|PMID:24338473
Biological Process	GO:0032361	pyridoxal phosphate catabolic process	Pdxp	IDA		Mouse	MGI:MGI:5545856|PMID:24338687
Biological Process	GO:0032361	pyridoxal phosphate catabolic process	Pdxp	IDA		Mouse	MGI:MGI:6695679|PMID:25783190
Biological Process	GO:0032465	regulation of cytokinesis	PDXP	IMP		Human	PMID:15580268
Biological Process	GO:0007088	regulation of mitotic nuclear division	PDXP	IMP		Human	PMID:15580268

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern