Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PDZD8
  • Mouse genes Pdzd8
  • Rat genes Pdzd8
  • Zfish genes pdzd8
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pdzd8

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	PDZD8	IPI	UniProtKB:A0A0F6AZQ1	Human	PMID:34237247
Cellular Component	GO:0005789	endoplasmic reticulum membrane	PDZD8	IDA		Human	PMID:29097544
Cellular Component	GO:0005789	endoplasmic reticulum membrane	Pdzd8	IDA		Mouse	MGI:MGI:6094720|PMID:29097544
Cellular Component	GO:0016020	membrane	PDZD8	HDA		Human	PMID:19946888
Cellular Component	GO:0044233	mitochondria-associated endoplasmic reticulum membrane	PDZD8	IDA		Human	PMID:29097544
Cellular Component	GO:0044233	mitochondria-associated endoplasmic reticulum membrane	Pdzd8	IDA		Mouse	MGI:MGI:6094720|PMID:29097544
Biological Process	GO:0007010	cytoskeleton organization	PDZD8	IMP		Human	PMID:21834987
Biological Process	GO:0051560	mitochondrial calcium ion homeostasis	PDZD8	IDA		Human	PMID:29097544
Biological Process	GO:0051560	mitochondrial calcium ion homeostasis	Pdzd8	IDA		Mouse	MGI:MGI:6094720|PMID:29097544
Biological Process	GO:1990456	mitochondrion-endoplasmic reticulum membrane tethering	PDZD8	IDA		Human	PMID:29097544
Biological Process	GO:1990456	mitochondrion-endoplasmic reticulum membrane tethering	Pdzd8	IDA		Mouse	MGI:MGI:6094720|PMID:29097544
Biological Process	GO:0022604	regulation of cell morphogenesis	PDZD8	IMP		Human	PMID:21834987

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern