Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PEA15
  • Mouse genes Pea15a
  • Rat genes Pea15
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pea15a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	PEA15	IPI	UniProtKB:Q13158	Human	PMID:10442631
Molecular Function	GO:0005515	protein binding	PEA15	IPI	UniProtKB:Q14790	Human	PMID:10442631
Molecular Function	GO:0005515	protein binding	PEA15	IPI	UniProtKB:P28482	Human	PMID:17255949
Molecular Function	GO:0005515	protein binding	PEA15	IPI	UniProtKB:Q9NYB0	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	PEA15	IPI	UniProtKB:P27361	Human	PMID:21900206
Molecular Function	GO:0005515	protein binding	PEA15	IPI	UniProtKB:P27361	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PEA15	IPI	UniProtKB:P28482	Human	PMID:32296183
Cellular Component	GO:0005829	cytosol	PEA15	IDA		Human	GO_REF:0000052
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	PEA15	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	PEA15	IDA		Human	GO_REF:0000052
Biological Process	GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors	PEA15	IDA		Human	PMID:10442631
Biological Process	GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors	Pea15a	IDA		Mouse	PMID:10588860
Biological Process	GO:0046325	negative regulation of glucose import	PEA15	IDA		Human	PMID:9670003
Biological Process	GO:1902043	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors	Pea15a	IDA		Mouse	PMID:10588860
Biological Process	GO:0043278	response to morphine	Pea15	IEP		Rat	PMID:19758790|RGD:2326031

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern