Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PELI1
  • Mouse genes Peli1
  • Rat genes Peli1
  • Zfish genes peli1a,peli1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Peli1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	PELI1	IPI	UniProtKB:P51617	Human	PMID:12496252
Molecular Function	GO:0005515	protein binding	PELI1	IPI	UniProtKB:Q9NWZ3	Human	PMID:12496252
Molecular Function	GO:0005515	protein binding	PELI1	IPI	UniProtKB:P51617	Human	PMID:16884718
Molecular Function	GO:0005515	protein binding	PELI1	IPI	UniProtKB:P51617	Human	PMID:19264966
Molecular Function	GO:0005515	protein binding	PELI1	IPI	UniProtKB:Q9NWZ3	Human	PMID:19264966
Molecular Function	GO:0005515	protein binding	PELI1	IPI	UniProtKB:Q08AM6	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PELI1	IPI	UniProtKB:Q15645	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PELI1	IPI	UniProtKB:P51617	Human	PMID:29883609
Molecular Function	GO:0005515	protein binding	PELI1	IPI	UniProtKB:Q13546	Human	PMID:29883609
Molecular Function	GO:0005515	protein binding	PELI1	IPI	UniProtKB:Q9Y572	Human	PMID:29883609
Molecular Function	GO:0005515	protein binding	PELI1	IPI	UniProtKB:O14653	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PELI1	IPI	UniProtKB:P02545	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PELI1	IPI	UniProtKB:P80188	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PELI1	IPI	UniProtKB:Q13442	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PELI1	IPI	UniProtKB:Q15735	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PELI1	IPI	UniProtKB:Q6ZS10	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PELI1	IPI	UniProtKB:Q8N137	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PELI1	IPI	UniProtKB:Q9H3D4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PELI1	IPI	UniProtKB:Q9H426	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PELI1	IPI	UniProtKB:Q9NWZ3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PELI1	IPI	UniProtKB:Q9Y3C0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PELI1	IPI	UniProtKB:D3DTS7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PELI1	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Peli1	IPI	UniProtKB:Q60855|UniProtKB:Q9QZL0	Mouse	MGI:MGI:6163945|PMID:29883609
Molecular Function	GO:0005515	protein binding	Peli1	IPI	MGI:MGI:97897	Mouse	PMID:21874024
Molecular Function	GO:0005515	protein binding	Peli1	IPI	UniProtKB:Q13546	Mouse	PMID:19734906
Molecular Function	GO:0005515	protein binding	Peli1	IPI	PR:Q60855	Mouse	PMID:19734906
Molecular Function	GO:0005515	protein binding	Peli1	IPI	PR:000050395	Mouse	PMID:31537781
Molecular Function	GO:0061630	ubiquitin protein ligase activity	PELI1	EXP		Human	PMID:29883609
Molecular Function	GO:0061630	ubiquitin protein ligase activity	PELI1	IDA		Human	PMID:29883609
Molecular Function	GO:0061630	ubiquitin protein ligase activity	Peli1	IDA		Mouse	PMID:19734906
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	Peli1	IDA		Mouse	PMID:21874024
Cellular Component	GO:0005634	nucleus	Peli1	IDA		Mouse	PMID:21874024
Biological Process	GO:0007420	brain development	peli1b	IMP	ZFIN:ZDB-MRPHLNO-190722-2	Zfish	PMID:30716445
Biological Process	GO:0060546	negative regulation of necroptotic process	PELI1	IMP		Human	PMID:29883609
Biological Process	GO:0060546	negative regulation of necroptotic process	Peli1	IMP		Mouse	MGI:MGI:6163945|PMID:29883609
Biological Process	GO:0032088	negative regulation of NF-kappaB transcription factor activity	Peli1	IMP	MGI:MGI:4361448	Mouse	PMID:21874024
Biological Process	GO:0050868	negative regulation of T cell activation	Peli1	IMP	MGI:MGI:4361448	Mouse	PMID:21874024
Biological Process	GO:0042130	negative regulation of T cell proliferation	Peli1	IMP	MGI:MGI:4361448	Mouse	PMID:21874024
Biological Process	GO:0050871	positive regulation of B cell activation	Peli1	IMP	MGI:MGI:4361448	Mouse	PMID:19734906
Biological Process	GO:0030890	positive regulation of B cell proliferation	Peli1	IMP	MGI:MGI:4361448	Mouse	PMID:19734906
Biological Process	GO:0001819	positive regulation of cytokine production	Peli1	IMP	MGI:MGI:4361448	Mouse	PMID:19734906
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	Peli1	IMP	MGI:MGI:4361448	Mouse	PMID:19734906
Biological Process	GO:0031398	positive regulation of protein ubiquitination	Peli1	IMP	MGI:MGI:4361448	Mouse	PMID:19734906
Biological Process	GO:0034141	positive regulation of toll-like receptor 3 signaling pathway	Peli1	IMP	MGI:MGI:4361448	Mouse	PMID:19734906
Biological Process	GO:0034145	positive regulation of toll-like receptor 4 signaling pathway	Peli1	IMP	MGI:MGI:4361448	Mouse	PMID:19734906
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	PELI1	IMP		Human	PMID:29883609
Biological Process	GO:0070936	protein K48-linked ubiquitination	PELI1	IMP		Human	PMID:29883609
Biological Process	GO:0070936	protein K48-linked ubiquitination	Peli1	IDA		Mouse	PMID:21874024
Biological Process	GO:0070534	protein K63-linked ubiquitination	PELI1	IMP		Human	PMID:29883609
Biological Process	GO:0000209	protein polyubiquitination	Peli1	IMP	MGI:MGI:4361448	Mouse	PMID:21874024
Biological Process	GO:0043331	response to dsRNA	Peli1	IMP	MGI:MGI:4361448	Mouse	PMID:19734906
Biological Process	GO:0032496	response to lipopolysaccharide	PELI1	IDA		Human	PMID:19193853
Biological Process	GO:0032496	response to lipopolysaccharide	Peli1	IMP	MGI:MGI:4361448	Mouse	PMID:19734906
Biological Process	GO:0042110	T cell activation	Peli1	IMP	MGI:MGI:4361448	Mouse	PMID:21874024
Biological Process	GO:0042098	T cell proliferation	Peli1	IMP	MGI:MGI:4361448	Mouse	PMID:21874024

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern