Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PEMT
  • Mouse genes Pemt
  • Rat genes Pemt
  • Zfish genes pemt
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pemt

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008429	phosphatidylethanolamine binding	Pemt	IDA		Rat	PMID:8344945|RGD:729486
Molecular Function	GO:0004608	phosphatidylethanolamine N-methyltransferase activity	Pemt	IDA		Rat	PMID:8344945|RGD:729486
Molecular Function	GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	Pemt	IMP		Mouse	PMID:25667419
Molecular Function	GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	Pemt	IDA		Rat	PMID:8344945|RGD:729486
Cellular Component	GO:0031526	brush border membrane	Pemt	IDA		Rat	PMID:17614848|RGD:1642368
Cellular Component	GO:0005829	cytosol	PEMT	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005783	endoplasmic reticulum	PEMT	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005789	endoplasmic reticulum membrane	Pemt	IDA		Mouse	PMID:12072432
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	PEMT	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016020	membrane	Pemt	IDA		Rat	PMID:8344945|RGD:729486
Cellular Component	GO:0005739	mitochondrion	PEMT	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	Pemt	HDA		Mouse	PMID:14651853
Cellular Component	GO:0042383	sarcolemma	Pemt	IDA		Rat	PMID:9406167|RGD:1642376
Biological Process	GO:0001835	blastocyst hatching	Pemt	IMP		Mouse	PMID:27869233
Biological Process	GO:0006650	glycerophospholipid metabolic process	Pemt	IMP		Rat	PMID:8445336|RGD:1642382
Biological Process	GO:0008285	negative regulation of cell population proliferation	Pemt	IMP		Rat	PMID:7929120|RGD:1642378
Biological Process	GO:0006656	phosphatidylcholine biosynthetic process	Pemt	IDA		Rat	PMID:8344945|RGD:729486
Biological Process	GO:0120162	positive regulation of cold-induced thermogenesis	Pemt	IMP		Mouse	MGI:MGI:5694279|PMID:26113536
Biological Process	GO:0050747	positive regulation of lipoprotein metabolic process	Pemt	IMP		Rat	PMID:12091487|RGD:1626402
Biological Process	GO:0043200	response to amino acid	Pemt	IEP		Rat	PMID:16391469|RGD:1642371
Biological Process	GO:0045471	response to ethanol	Pemt	IEP		Rat	PMID:17156888|RGD:1642369
Biological Process	GO:0007584	response to nutrient	Pemt	IEP		Rat	PMID:9566595|RGD:1642373
Biological Process	GO:0033273	response to vitamin	Pemt	IDA		Rat	PMID:7766014|RGD:1642377
Biological Process	GO:0009410	response to xenobiotic stimulus	Pemt	IDA		Rat	PMID:9406167|RGD:1642376
Biological Process	GO:0046498	S-adenosylhomocysteine metabolic process	Pemt	IDA		Rat	PMID:8344945|RGD:729486
Biological Process	GO:0046500	S-adenosylmethionine metabolic process	Pemt	IDA		Rat	PMID:8344945|RGD:729486
Biological Process	GO:0006686	sphingomyelin biosynthetic process	Pemt	IMP		Mouse	PMID:25667419

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern