Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PER3
  • Mouse genes Per3
  • Rat genes Per3
  • Zfish genes per3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Per3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019900	kinase binding	Per3	IPI	UniProtKB:P49674	Mouse	MGI:MGI:5567915|PMID:15917222
Molecular Function	GO:0005515	protein binding	PER3	IPI	UniProtKB:O96017	Human	PMID:21070773
Molecular Function	GO:0005515	protein binding	Per3	IPI	UniProtKB:O35973|UniProtKB:O54943|UniProtKB:P97784|UniProtKB:Q9R194	Mouse	MGI:MGI:3027197|PMID:14701732
Molecular Function	GO:0005515	protein binding	Per3	IPI	PR:O35973	Mouse	PMID:9856466
Molecular Function	GO:0005515	protein binding	Per3	IPI	PR:O54943	Mouse	PMID:9856466
Molecular Function	GO:0031625	ubiquitin protein ligase binding	Per3	IPI	UniProtKB:Q9UKB1|UniProtKB:Q9Y297	Mouse	MGI:MGI:5567915|PMID:15917222
Cellular Component	GO:0005737	cytoplasm	PER3	IDA		Human	PMID:26903630
Cellular Component	GO:0005634	nucleus	PER3	IDA		Human	PMID:26903630
Biological Process	GO:0032922	circadian regulation of gene expression	per3	IMP	ZFIN:ZDB-MRPHLNO-081125-3	Zfish	PMID:18597743
Biological Process	GO:0007623	circadian rhythm	Per3	IDA		Mouse	PMID:12843397
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	PER3	IDA		Human	PMID:26903630
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Per3	IDA		Mouse	PMID:9989497
Biological Process	GO:0009648	photoperiodism	per3	IEP		Zfish	PMID:10894777
Biological Process	GO:0009648	photoperiodism	per3	IEP		Zfish	PMID:11517315
Biological Process	GO:0050821	protein stabilization	PER3	IMP		Human	PMID:26903630
Biological Process	GO:0045187	regulation of circadian sleep/wake cycle, sleep	PER3	IMP		Human	PMID:17346965
Biological Process	GO:0045187	regulation of circadian sleep/wake cycle, sleep	PER3	IMP		Human	PMID:19716732
Biological Process	GO:0045187	regulation of circadian sleep/wake cycle, sleep	PER3	IMP		Human	PMID:24439663
Biological Process	GO:0045187	regulation of circadian sleep/wake cycle, sleep	PER3	IMP		Human	PMID:24577121
Biological Process	GO:0045187	regulation of circadian sleep/wake cycle, sleep	PER3	IMP		Human	PMID:26903630
Biological Process	GO:0045187	regulation of circadian sleep/wake cycle, sleep	Per3	IMP		Mouse	MGI:MGI:5300112|PMID:21957163

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern