Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PERP
  • Mouse genes Perp
  • Rat genes Perp
  • Zfish genes perp
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Perp

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	PERP	IPI	UniProtKB:O95870	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PERP	IPI	UniProtKB:P21145	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PERP	IPI	UniProtKB:O60333-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PERP	IPI	UniProtKB:O76024	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PERP	IPI	UniProtKB:P04792	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PERP	IPI	UniProtKB:P14136	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PERP	IPI	UniProtKB:P28799	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PERP	IPI	UniProtKB:Q8WXH2	Human	PMID:32814053
Cellular Component	GO:0005794	Golgi apparatus	Perp	IDA		Mouse	PMID:10733530
Cellular Component	GO:0005739	mitochondrion	Perp	HDA		Mouse	PMID:14651853
Cellular Component	GO:0005739	mitochondrion	Perp	IDA		Mouse	PMID:10733530
Cellular Component	GO:0005886	plasma membrane	Perp	IDA		Mouse	PMID:10733530
Biological Process	GO:0097202	activation of cysteine-type endopeptidase activity	PERP	IDA		Human	PMID:18387192
Biological Process	GO:0097186	amelogenesis	Perp	IMP	MGI:MGI:2683069	Mouse	PMID:21285247
Biological Process	GO:1902262	apoptotic process involved in blood vessel morphogenesis	perp	IMP	ZFIN:ZDB-MRPHLNO-170306-11	Zfish	PMID:27834691
Biological Process	GO:0002934	desmosome organization	Perp	IMP	MGI:MGI:2683069	Mouse	PMID:21285247
Biological Process	GO:0034113	heterotypic cell-cell adhesion	Perp	IMP	MGI:MGI:2683069	Mouse	PMID:21285247
Biological Process	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator	Perp	IDA		Mouse	PMID:10733530
Biological Process	GO:0007219	Notch signaling pathway	Perp	IDA		Mouse	PMID:23117660
Biological Process	GO:0045862	positive regulation of proteolysis	PERP	IDA		Human	PMID:18387192
Biological Process	GO:0042981	regulation of apoptotic process	perp	IMP	ZFIN:ZDB-MRPHLNO-050204-3	Zfish	PMID:15529176
Biological Process	GO:0042981	regulation of apoptotic process	perp	IMP		Zfish	PMID:15529176
Biological Process	GO:0009411	response to UV	perp	IMP	ZFIN:ZDB-MRPHLNO-050204-3	Zfish	PMID:15529176

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern