Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Pex5

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes PEX5
- Mouse genes Pex5
- Rat genes Pex5
- Zfish genes pex5
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pex5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019899	enzyme binding	PEX5	IPI	UniProtKB:Q9UHK6-1	Human	PMID:11060344
Molecular Function	GO:0019899	enzyme binding	PEX5	IPI	UniProtKB:Q9BY49	Human	PMID:11669066
Molecular Function	GO:0005052	peroxisome matrix targeting signal-1 binding	PEX5	IDA		Human	PMID:10514471
Molecular Function	GO:0005052	peroxisome matrix targeting signal-1 binding	PEX5	IDA		Human	PMID:11463335
Molecular Function	GO:0005052	peroxisome matrix targeting signal-1 binding	PEX5	IDA		Human	PMID:17157249
Molecular Function	GO:0005052	peroxisome matrix targeting signal-1 binding	PEX5	IPI	UniProtKB:P22307	Human	PMID:21375735
Molecular Function	GO:0005052	peroxisome matrix targeting signal-1 binding	PEX5	IDA		Human	PMID:21976670
Molecular Function	GO:0005052	peroxisome matrix targeting signal-1 binding	PEX5	IDA		Human	PMID:26344566
Molecular Function	GO:0033328	peroxisome membrane targeting sequence binding	PEX5	IPI	UniProtKB:O75381	Human	PMID:21976670
Molecular Function	GO:0000268	peroxisome targeting sequence binding	PEX5	IDA		Human	PMID:18346465
Molecular Function	GO:0005515	protein binding	PEX5	IPI	UniProtKB:P30044	Human	PMID:10514471
Molecular Function	GO:0005515	protein binding	PEX5	IPI	UniProtKB:P30044-2	Human	PMID:10514471
Molecular Function	GO:0005515	protein binding	PEX5	IPI	UniProtKB:O00623	Human	PMID:10562279
Molecular Function	GO:0005515	protein binding	PEX5	IPI	UniProtKB:O00623	Human	PMID:10837480
Molecular Function	GO:0005515	protein binding	PEX5	IPI	UniProtKB:O60683	Human	PMID:10837480
Molecular Function	GO:0005515	protein binding	PEX5	IPI	UniProtKB:O00623	Human	PMID:12096124
Molecular Function	GO:0005515	protein binding	PEX5	IPI	UniProtKB:O75381	Human	PMID:12096124
Molecular Function	GO:0005515	protein binding	PEX5	IPI	UniProtKB:O75381	Human	PMID:12488033
Molecular Function	GO:0005515	protein binding	PEX5	IPI	UniProtKB:P21549	Human	PMID:15911627
Molecular Function	GO:0005515	protein binding	PEX5	IPI	UniProtKB:O75381	Human	PMID:19197237
Molecular Function	GO:0005515	protein binding	PEX5	IPI	UniProtKB:O75381	Human	PMID:19584060
Molecular Function	GO:0005515	protein binding	PEX5	IPI	UniProtKB:P22307	Human	PMID:19584060
Molecular Function	GO:0005515	protein binding	PEX5	IPI	UniProtKB:Q9BSI4	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	PEX5	IPI	UniProtKB:O75381	Human	PMID:21525035
Molecular Function	GO:0005515	protein binding	PEX5	IPI	UniProtKB:O75381	Human	PMID:24235149
Molecular Function	GO:0005515	protein binding	PEX5	IPI	UniProtKB:A8K3Q9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PEX5	IPI	UniProtKB:O14734	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PEX5	IPI	UniProtKB:P06703	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PEX5	IPI	UniProtKB:P07195	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PEX5	IPI	UniProtKB:Q49A88	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PEX5	IPI	UniProtKB:Q68DY9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PEX5	IPI	UniProtKB:Q6IMN6	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PEX5	IPI	UniProtKB:Q6IPH7	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PEX5	IPI	UniProtKB:Q6NSB6	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PEX5	IPI	UniProtKB:Q75MR5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PEX5	IPI	UniProtKB:Q8N5N8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PEX5	IPI	UniProtKB:Q8WTR4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PEX5	IPI	UniProtKB:Q9NZ81	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PEX5	IPI	UniProtKB:O00628	Human	PMID:25538232
Molecular Function	GO:0005515	protein binding	PEX5	IPI	UniProtKB:P63010	Human	PMID:35044719
Molecular Function	GO:0005515	protein binding	PEX5	IPI	UniProtKB:O75381	Human	PMID:9653144
Molecular Function	GO:0005515	protein binding	PEX5	IPI	UniProtKB:Q99489	Human	PMID:9820813
Molecular Function	GO:0140597	protein carrier chaperone	PEX5	IDA		Human	PMID:16314507
Molecular Function	GO:0140597	protein carrier chaperone	PEX5	IDA		Human	PMID:17157249
Molecular Function	GO:0140597	protein carrier chaperone	PEX5	IDA		Human	PMID:21976670
Molecular Function	GO:0140597	protein carrier chaperone	PEX5	IDA		Human	PMID:24235149
Molecular Function	GO:0140597	protein carrier chaperone	PEX5	IDA		Human	PMID:24662292
Molecular Function	GO:0140597	protein carrier chaperone	PEX5	IDA		Human	PMID:25538232
Molecular Function	GO:0140597	protein carrier chaperone	PEX5	IDA		Human	PMID:26344566
Molecular Function	GO:0140597	protein carrier chaperone	PEX5	IDA		Human	PMID:28765278
Molecular Function	GO:0140597	protein carrier chaperone	PEX5	IMP		Human	PMID:33389129
Molecular Function	GO:0044183	protein folding chaperone	PEX5	EXP		Human	PMID:16403517
Molecular Function	GO:0044183	protein folding chaperone	PEX5	IDA		Human	PMID:16403517
Molecular Function	GO:0031267	small GTPase binding	PEX5	IPI	UniProtKB:Q92930	Human	PMID:18346465
Cellular Component	GO:0005737	cytoplasm	PEX5	IDA		Human	PMID:10514471
Cellular Component	GO:0005829	cytosol	PEX5	IDA		Human	PMID:16314507
Cellular Component	GO:0005829	cytosol	PEX5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	Pex5	IDA		Rat	PMID:11415446\|RGD:4892111
Cellular Component	GO:0005794	Golgi apparatus	PEX5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016020	membrane	PEX5	IDA		Human	PMID:10514471
Cellular Component	GO:0016020	membrane	Pex5	IDA		Rat	PMID:11415446\|RGD:4892111
Cellular Component	GO:0005739	mitochondrion	Pex5	IMP	MGI:MGI:2154454	Mouse	MGI:MGI:2151292\|PMID:11583975
Cellular Component	GO:0005782	peroxisomal matrix	PEX5	IDA		Human	PMID:16314507
Cellular Component	GO:0005782	peroxisomal matrix	PEX5	IDA		Human	PMID:24662292
Cellular Component	GO:0005782	peroxisomal matrix	PEX5	IMP		Human	PMID:33389129
Cellular Component	GO:0005778	peroxisomal membrane	PEX5	HDA		Human	PMID:21525035
Cellular Component	GO:0005778	peroxisomal membrane	Pex5	IDA		Rat	PMID:11397814\|RGD:1625410
Cellular Component	GO:0005778	peroxisomal membrane	Pex5	IDA		Rat	PMID:14561759\|RGD:1580664
Cellular Component	GO:0005777	peroxisome	PEX5	IDA		Human	PMID:11829486
Cellular Component	GO:0005777	peroxisome	PEX5	IDA		Human	PMID:21375735
Cellular Component	GO:0005777	peroxisome	Pex5	IDA		Rat	PMID:11397814\|RGD:1625410
Cellular Component	GO:0005777	peroxisome	Pex5	IDA		Rat	PMID:11415446\|RGD:4892111
Cellular Component	GO:0032991	protein-containing complex	PEX5	IDA		Human	PMID:19584060
Cellular Component	GO:0032991	protein-containing complex	Pex5	IDA		Rat	PMID:11397814\|RGD:1625410
Biological Process	GO:0048468	cell development	Pex5	IMP	MGI:MGI:2154454	Mouse	PMID:9288097
Biological Process	GO:0044255	cellular lipid metabolic process	Pex5	IMP	MGI:MGI:2384516	Mouse	PMID:16484321
Biological Process	GO:0034614	cellular response to reactive oxygen species	PEX5	IDA		Human	PMID:26344566
Biological Process	GO:0021795	cerebral cortex cell migration	Pex5	IMP	MGI:MGI:2154454	Mouse	PMID:10653000
Biological Process	GO:0021795	cerebral cortex cell migration	Pex5	IMP	MGI:MGI:2154454	Mouse	PMID:9288097
Biological Process	GO:0021895	cerebral cortex neuron differentiation	Pex5	IMP	MGI:MGI:2154454	Mouse	PMID:9288097
Biological Process	GO:0007029	endoplasmic reticulum organization	Pex5	IMP	MGI:MGI:2176228,MGI:MGI:2384516	Mouse	PMID:15732085
Biological Process	GO:0006635	fatty acid beta-oxidation	Pex5	IMP	MGI:MGI:2154454	Mouse	PMID:9288097
Biological Process	GO:0006635	fatty acid beta-oxidation	Pex5	IMP	MGI:MGI:2176228,MGI:MGI:2384516	Mouse	PMID:17442273
Biological Process	GO:0007006	mitochondrial membrane organization	Pex5	IMP	MGI:MGI:2154454	Mouse	PMID:11583975
Biological Process	GO:0007005	mitochondrion organization	Pex5	IMP	MGI:MGI:2176228,MGI:MGI:2384516	Mouse	PMID:15732085
Biological Process	GO:0031333	negative regulation of protein-containing complex assembly	PEX5	IDA		Human	PMID:21976670
Biological Process	GO:0050905	neuromuscular process	Pex5	IMP	MGI:MGI:2154454	Mouse	PMID:9288097
Biological Process	GO:0001764	neuron migration	Pex5	IMP	MGI:MGI:2154454	Mouse	PMID:10653000
Biological Process	GO:0001764	neuron migration	Pex5	IMP	MGI:MGI:2154454	Mouse	PMID:14586000
Biological Process	GO:0001764	neuron migration	Pex5	IMP	MGI:MGI:2154454	Mouse	PMID:9288097
Biological Process	GO:0007031	peroxisome organization	Pex5	IDA		Mouse	PMID:14586000
Biological Process	GO:0007031	peroxisome organization	Pex5	IMP	MGI:MGI:2154454	Mouse	PMID:9288097
Biological Process	GO:0007031	peroxisome organization	Pex5	IMP	MGI:MGI:2176228,MGI:MGI:2384516	Mouse	PMID:15732085
Biological Process	GO:0000425	pexophagy	PEX5	IDA		Human	PMID:26344566
Biological Process	GO:0040018	positive regulation of multicellular organism growth	Pex5	IMP	MGI:MGI:2154454	Mouse	PMID:10653000
Biological Process	GO:0040018	positive regulation of multicellular organism growth	Pex5	IMP	MGI:MGI:2154454	Mouse	PMID:9288097
Biological Process	GO:0016558	protein import into peroxisome matrix	PEX5	IMP		Human	PMID:11463335
Biological Process	GO:0016558	protein import into peroxisome matrix	PEX5	IDA		Human	PMID:16314507
Biological Process	GO:0016558	protein import into peroxisome matrix	PEX5	IDA		Human	PMID:17157249
Biological Process	GO:0016558	protein import into peroxisome matrix	PEX5	IGI	UniProtKB:O09012	Human	PMID:18346465
Biological Process	GO:0016558	protein import into peroxisome matrix	PEX5	IDA		Human	PMID:21976670
Biological Process	GO:0016558	protein import into peroxisome matrix	PEX5	IDA		Human	PMID:24235149
Biological Process	GO:0016558	protein import into peroxisome matrix	PEX5	IDA		Human	PMID:24662292
Biological Process	GO:0016558	protein import into peroxisome matrix	PEX5	IDA		Human	PMID:25538232
Biological Process	GO:0016558	protein import into peroxisome matrix	PEX5	IDA		Human	PMID:26344566
Biological Process	GO:0016558	protein import into peroxisome matrix	PEX5	IMP		Human	PMID:33389129
Biological Process	GO:0016558	protein import into peroxisome matrix	Pex5	IMP		Mouse	MGI:MGI:5442515\|PMID:11463335
Biological Process	GO:0016560	protein import into peroxisome matrix, docking	PEX5	IDA		Human	PMID:21976670
Biological Process	GO:0016562	protein import into peroxisome matrix, receptor recycling	PEX5	IDA		Human	PMID:11336669
Biological Process	GO:0016562	protein import into peroxisome matrix, receptor recycling	PEX5	IDA		Human	PMID:22371489
Biological Process	GO:0016562	protein import into peroxisome matrix, receptor recycling	PEX5	IDA		Human	PMID:29884772
Biological Process	GO:0044721	protein import into peroxisome matrix, substrate release	PEX5	IDA		Human	PMID:26344566
Biological Process	GO:0045046	protein import into peroxisome membrane	PEX5	IMP		Human	PMID:14709540
Biological Process	GO:0000038	very long-chain fatty acid metabolic process	Pex5	IMP	MGI:MGI:2154454	Mouse	PMID:10653000

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.