Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PGK1
  • Mouse genes Pgk1
  • Rat genes Pgk1,RGD1560402
  • Zfish genes pgk1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pgk1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0043531	ADP binding	Pgk1	IDA		Rat	PMID:6405813|RGD:2302859
Molecular Function	GO:0005524	ATP binding	Pgk1	IMP		Rat	PMID:3091090|RGD:2302860
Molecular Function	GO:0004618	phosphoglycerate kinase activity	PGK1	EXP		Human	PMID:1278465
Molecular Function	GO:0004618	phosphoglycerate kinase activity	PGK1	EXP		Human	PMID:5009693
Molecular Function	GO:0004618	phosphoglycerate kinase activity	PGK1	IMP		Human	PMID:7391028
Molecular Function	GO:0004618	phosphoglycerate kinase activity	Pgk1	IDA		Mouse	PMID:4817529
Molecular Function	GO:0004618	phosphoglycerate kinase activity	Pgk1	IDA		Mouse	PMID:17248765
Molecular Function	GO:0004618	phosphoglycerate kinase activity	Pgk1	IDA		Mouse	PMID:943046
Molecular Function	GO:0004618	phosphoglycerate kinase activity	Pgk1	IDA		Mouse	PMID:6852525
Molecular Function	GO:0004618	phosphoglycerate kinase activity	Pgk1	IDA		Rat	PMID:1834654|RGD:1599371
Molecular Function	GO:0004618	phosphoglycerate kinase activity	Pgk1	IMP		Rat	PMID:3091090|RGD:2302860
Molecular Function	GO:0004618	phosphoglycerate kinase activity	Pgk1	IDA		Rat	PMID:6405813|RGD:2302859
Molecular Function	GO:0005515	protein binding	PGK1	IPI	UniProtKB:P04406	Human	PMID:20392205
Molecular Function	GO:0005515	protein binding	PGK1	IPI	UniProtKB:P12004	Human	PMID:20849852
Molecular Function	GO:0005515	protein binding	PGK1	IPI	UniProtKB:P12004	Human	PMID:26030842
Molecular Function	GO:0005515	protein binding	PGK1	IPI	UniProtKB:O15379	Human	PMID:26356530
Molecular Function	GO:0005515	protein binding	PGK1	IPI	UniProtKB:Q8TDX7	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	Pgk1	IPI	UniProtKB:Q924N4	Mouse	MGI:MGI:6221361|PMID:27782176
Molecular Function	GO:0047134	protein-disulfide reductase (NAD(P)) activity	PGK1	IMP		Human	PMID:11130727
Cellular Component	GO:0005829	cytosol	Pgk1	IDA		Mouse	PMID:33274589
Cellular Component	GO:0005829	cytosol	Pgk1	IDA		Mouse	PMID:4262895
Cellular Component	GO:0005829	cytosol	Pgk1	IDA		Rat	PMID:1834654|RGD:1599371
Cellular Component	GO:0070062	extracellular exosome	PGK1	HDA		Human	PMID:11487543
Cellular Component	GO:0070062	extracellular exosome	PGK1	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	PGK1	HDA		Human	PMID:20458337
Cellular Component	GO:0070062	extracellular exosome	PGK1	HDA		Human	PMID:23533145
Cellular Component	GO:0005615	extracellular space	PGK1	IDA		Human	PMID:11130727
Cellular Component	GO:0016020	membrane	PGK1	HDA		Human	PMID:19946888
Cellular Component	GO:0045121	membrane raft	PGK1	IDA		Human	PMID:25204797
Biological Process	GO:0061621	canonical glycolysis	Pgk1	IGI	MGI:MGI:3780541	Mouse	PMID:30174313
Biological Process	GO:0005975	carbohydrate metabolic process	Pgk1	IDA		Rat	PMID:1834654|RGD:1599371
Biological Process	GO:0071456	cellular response to hypoxia	PGK1	IDA		Human	PMID:11130727
Biological Process	GO:0061550	cranial ganglion development	pgk1	IMP	ZFIN:ZDB-GENO-211004-1	Zfish	PMID:32338604
Biological Process	GO:0061550	cranial ganglion development	pgk1	IMP	ZFIN:ZDB-MRPHLNO-210223-7	Zfish	PMID:32338604
Biological Process	GO:0061550	cranial ganglion development	pgk1	IMP	ZFIN:ZDB-GENO-211004-5	Zfish	PMID:32338604
Biological Process	GO:0061550	cranial ganglion development	pgk1	IMP	ZFIN:ZDB-MRPHLNO-210223-6	Zfish	PMID:32338604
Biological Process	GO:0061550	cranial ganglion development	pgk1	IMP	ZFIN:ZDB-MRPHLNO-210223-5	Zfish	PMID:32338604
Biological Process	GO:0061550	cranial ganglion development	pgk1	IMP	ZFIN:ZDB-GENO-211004-2	Zfish	PMID:32338604
Biological Process	GO:0030855	epithelial cell differentiation	PGK1	IEP		Human	PMID:21492153
Biological Process	GO:0006094	gluconeogenesis	Pgk1	IGI	MGI:MGI:106918	Mouse	PMID:19643083
Biological Process	GO:0006094	gluconeogenesis	Pgk1	IDA		Rat	PMID:15720133|RGD:2302795
Biological Process	GO:0006094	gluconeogenesis	Pgk1	IMP		Rat	PMID:3091090|RGD:2302860
Biological Process	GO:0006096	glycolytic process	PGK1	IMP		Human	PMID:7391028
Biological Process	GO:0006096	glycolytic process	Pgk1	IDA		Mouse	PMID:15665293
Biological Process	GO:0006096	glycolytic process	Pgk1	IMP		Rat	PMID:3091090|RGD:2302860
Biological Process	GO:0006096	glycolytic process	Pgk1	IDA		Rat	PMID:6405813|RGD:2302859
Biological Process	GO:0060119	inner ear receptor cell development	pgk1	IMP	ZFIN:ZDB-GENO-211004-5	Zfish	PMID:32338604
Biological Process	GO:0060119	inner ear receptor cell development	pgk1	IMP	ZFIN:ZDB-GENO-211004-3	Zfish	PMID:32338604
Biological Process	GO:0016525	negative regulation of angiogenesis	PGK1	IMP		Human	PMID:11130727
Biological Process	GO:0014016	neuroblast differentiation	pgk1	IMP	ZFIN:ZDB-GENO-211004-2	Zfish	PMID:32338604
Biological Process	GO:0071599	otic vesicle development	pgk1	IMP	ZFIN:ZDB-GENO-211004-2	Zfish	PMID:32338604
Biological Process	GO:0031639	plasminogen activation	PGK1	IMP		Human	PMID:11130727
Biological Process	GO:1903862	positive regulation of oxidative phosphorylation	pgk1	IMP	ZFIN:ZDB-MRPHLNO-170620-2	Zfish	PMID:28426667
Biological Process	GO:0001666	response to hypoxia	pgk1	IDA		Zfish	PMID:16709914

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern