Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PGLYRP2
  • Mouse genes Pglyrp2
  • Rat genes Pglyrp2
  • Zfish genes pglyrp2,pglyrp6
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pglyrp2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008745	N-acetylmuramoyl-L-alanine amidase activity	PGLYRP2	IDA		Human	PMID:14506276
Molecular Function	GO:0008745	N-acetylmuramoyl-L-alanine amidase activity	pglyrp2	IDA		Zfish	PMID:17892854
Molecular Function	GO:0008745	N-acetylmuramoyl-L-alanine amidase activity	pglyrp6	IDA		Zfish	PMID:17892854
Molecular Function	GO:0042834	peptidoglycan binding	PGLYRP2	IDA		Human	PMID:11461926
Molecular Function	GO:0016019	peptidoglycan immune receptor activity	PGLYRP2	IDA		Human	PMID:11461926
Cellular Component	GO:0070062	extracellular exosome	PGLYRP2	HDA		Human	PMID:23533145
Biological Process	GO:0051701	biological process involved in interaction with host	Pglyrp2	IMP	MGI:MGI:5297105	Mouse	PMID:20709292
Biological Process	GO:0042742	defense response to bacterium	pglyrp2	IDA		Zfish	PMID:17892854
Biological Process	GO:0042742	defense response to bacterium	pglyrp6	IMP		Zfish	PMID:18495251
Biological Process	GO:0042742	defense response to bacterium	pglyrp6	IDA		Zfish	PMID:17892854
Biological Process	GO:0050830	defense response to Gram-positive bacterium	PGLYRP2	IDA		Human	PMID:11461926
Biological Process	GO:0016045	detection of bacterium	PGLYRP2	IDA		Human	PMID:11461926
Biological Process	GO:0032827	negative regulation of natural killer cell differentiation involved in immune response	Pglyrp2	IMP	MGI:MGI:5297105	Mouse	PMID:20709292
Biological Process	GO:0032689	negative regulation of type II interferon production	Pglyrp2	IMP	MGI:MGI:5297105	Mouse	PMID:20709292
Biological Process	GO:0050727	regulation of inflammatory response	Pglyrp2	IMP	MGI:MGI:5297105	Mouse	PMID:19218085
Biological Process	GO:0050727	regulation of inflammatory response	Pglyrp2	IMP	MGI:MGI:5297105	Mouse	PMID:22048773

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern