Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PGLYRP4
  • Mouse genes Pglyrp4
  • Rat genes Pglyrp4
  • Zfish genes pglyrp5
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pglyrp4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008745	N-acetylmuramoyl-L-alanine amidase activity	pglyrp5	IDA		Zfish	PMID:17892854
Molecular Function	GO:0042834	peptidoglycan binding	PGLYRP4	IDA		Human	PMID:11461926
Molecular Function	GO:0042834	peptidoglycan binding	PGLYRP4	IDA		Human	PMID:16354652
Molecular Function	GO:0042834	peptidoglycan binding	PGLYRP4	IDA		Human	PMID:17502600
Molecular Function	GO:0016019	peptidoglycan immune receptor activity	PGLYRP4	IDA		Human	PMID:11461926
Molecular Function	GO:0046982	protein heterodimerization activity	PGLYRP4	IPI	UniProtKB:Q96LB9	Human	PMID:16354652
Cellular Component	GO:0032991	protein-containing complex	PGLYRP4	IDA		Human	PMID:16354652
Biological Process	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide	PGLYRP4	IDA		Human	PMID:16354652
Biological Process	GO:0051701	biological process involved in interaction with host	Pglyrp4	IMP	MGI:MGI:5297107	Mouse	PMID:20709292
Biological Process	GO:0042742	defense response to bacterium	pglyrp5	IMP	ZFIN:ZDB-MRPHLNO-071227-3	Zfish	PMID:17892854
Biological Process	GO:0042742	defense response to bacterium	pglyrp5	IDA		Zfish	PMID:17892854
Biological Process	GO:0050830	defense response to Gram-positive bacterium	PGLYRP4	IDA		Human	PMID:11461926
Biological Process	GO:0050830	defense response to Gram-positive bacterium	PGLYRP4	IDA		Human	PMID:16354652
Biological Process	GO:0016045	detection of bacterium	PGLYRP4	IDA		Human	PMID:11461926
Biological Process	GO:0031640	killing of cells of another organism	PGLYRP4	IDA		Human	PMID:16354652
Biological Process	GO:0032827	negative regulation of natural killer cell differentiation involved in immune response	Pglyrp4	IMP	MGI:MGI:5297107	Mouse	PMID:20709292
Biological Process	GO:0032689	negative regulation of type II interferon production	Pglyrp4	IMP	MGI:MGI:5297107	Mouse	PMID:20709292

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern