Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Pgr

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes PGR
- Mouse genes Pgr
- Rat genes Pgr
- Zfish genes pgr
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pgr

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051117	ATPase binding	PGR	IDA		Human	PMID:12058073
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	PGR	IDA		Human	PMID:17785366
Molecular Function	GO:0019899	enzyme binding	PGR	IPI	UniProtKB:P55345	Human	PMID:12039952
Molecular Function	GO:0042562	hormone binding	Pgr	IMP		Rat	PMID:11113338\|RGD:1601290
Molecular Function	GO:0042802	identical protein binding	PGR	IPI	UniProtKB:P06401	Human	PMID:17277083
Molecular Function	GO:0042802	identical protein binding	PGR	IPI	UniProtKB:P06401	Human	PMID:24909783
Molecular Function	GO:0004879	nuclear receptor activity	Pgr	IMP		Mouse	PMID:14681235
Molecular Function	GO:0003707	nuclear steroid receptor activity	Pgr	IDA		Mouse	PMID:16176985
Molecular Function	GO:0003707	nuclear steroid receptor activity	Pgr	IMP		Rat	PMID:11113338\|RGD:1601290
Molecular Function	GO:0003707	nuclear steroid receptor activity	pgr	IDA		Zfish	PMID:19741208
Molecular Function	GO:0003707	nuclear steroid receptor activity	pgr	IDA		Zfish	PMID:19741205
Molecular Function	GO:0003676	nucleic acid binding	PGR	EXP		Human	PMID:19553667
Molecular Function	GO:0005515	protein binding	PGR	IPI	UniProtKB:O95071	Human	PMID:12011095
Molecular Function	GO:0005515	protein binding	PGR	IPI	UniProtKB:P03372	Human	PMID:12612073
Molecular Function	GO:0005515	protein binding	PGR	IPI	UniProtKB:Q96GM5	Human	PMID:12917342
Molecular Function	GO:0005515	protein binding	PGR	IPI	UniProtKB:Q00403	Human	PMID:1517211
Molecular Function	GO:0005515	protein binding	PGR	IPI	UniProtKB:Q9H467	Human	PMID:17347654
Molecular Function	GO:0005515	protein binding	PGR	IPI	UniProtKB:P40763	Human	PMID:20876300
Molecular Function	GO:0005515	protein binding	PGR	IPI	UniProtKB:P40763	Human	PMID:21184768
Molecular Function	GO:0005515	protein binding	PGR	IPI	UniProtKB:P03372	Human	PMID:22396492
Molecular Function	GO:0005515	protein binding	PGR	IPI	UniProtKB:P03372	Human	PMID:26153859
Molecular Function	GO:0005515	protein binding	Pgr	IPI	UniProtKB:Q64127	Mouse	MGI:MGI:84614\|PMID:8978696
Molecular Function	GO:0005515	protein binding	Pgr	IPI	UniProtKB:P42227	Mouse	MGI:MGI:5437426\|PMID:20876300
Molecular Function	GO:0005515	protein binding	Pgr	IPI	UniProtKB:P42227	Mouse	MGI:MGI:5437422\|PMID:21184768
Molecular Function	GO:0005515	protein binding	Pgr	IPI	UniProtKB:P19785	Mouse	MGI:MGI:5819341\|PMID:22396492
Molecular Function	GO:0005515	protein binding	Pgr	IPI	RGD:2582	Rat	PMID:16020483\|RGD:7248707
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	PGR	IDA		Human	PMID:17785366
Molecular Function	GO:0043565	sequence-specific DNA binding	Pgr	IDA		Rat	PMID:17109827\|RGD:7248706
Molecular Function	GO:0005496	steroid binding	Pgr	IMP		Rat	PMID:11113338\|RGD:1601290
Molecular Function	GO:0005496	steroid binding	pgr	IDA		Zfish	PMID:19741205
Molecular Function	GO:0001223	transcription coactivator binding	PGR	IPI	UniProtKB:Q96PN7	Human	PMID:17015480
Cellular Component	GO:0030424	axon	Pgr	IDA		Rat	PMID:18720413\|RGD:7248705
Cellular Component	GO:0043679	axon terminus	Pgr	IDA		Rat	PMID:18720413\|RGD:7248705
Cellular Component	GO:0005737	cytoplasm	Pgr	IDA		Rat	PMID:10869808\|RGD:1601289
Cellular Component	GO:0005829	cytosol	Pgr	IDA		Rat	PMID:8344215\|RGD:1601291
Cellular Component	GO:0030425	dendrite	Pgr	IDA		Rat	PMID:18720413\|RGD:7248705
Cellular Component	GO:0043197	dendritic spine	Pgr	IDA		Rat	PMID:18720413\|RGD:7248705
Cellular Component	GO:0005783	endoplasmic reticulum	Pgr	IDA		Rat	PMID:18720413\|RGD:7248705
Cellular Component	GO:0005739	mitochondrion	Pgr	IDA		Rat	PMID:18720413\|RGD:7248705
Cellular Component	GO:0043005	neuron projection	Pgr	IDA		Rat	PMID:10869808\|RGD:1601289
Cellular Component	GO:0005634	nucleus	Pgr	IDA		Rat	PMID:10869808\|RGD:1601289
Cellular Component	GO:0005634	nucleus	Pgr	IDA		Rat	PMID:10965915\|RGD:1601282
Cellular Component	GO:0043204	perikaryon	Pgr	IDA		Rat	PMID:18720413\|RGD:7248705
Cellular Component	GO:0005886	plasma membrane	PGR	IMP		Human	PMID:22031296
Cellular Component	GO:0005886	plasma membrane	Pgr	IDA		Rat	PMID:22778216\|RGD:7248712
Biological Process	GO:0071391	cellular response to estrogen stimulus	Pgr	IEP		Rat	PMID:17272396\|RGD:152177689
Biological Process	GO:0071372	cellular response to follicle-stimulating hormone stimulus	Pgr	IEP		Rat	PMID:8344215\|RGD:1601291
Biological Process	GO:0071371	cellular response to gonadotropin stimulus	Pgr	IEP		Rat	PMID:8344215\|RGD:1601291
Biological Process	GO:0071373	cellular response to luteinizing hormone stimulus	Pgr	IEP		Rat	PMID:8344215\|RGD:1601291
Biological Process	GO:1904568	cellular response to wortmannin	Pgr	IEP		Rat	PMID:17272396\|RGD:152177689
Biological Process	GO:0016101	diterpenoid metabolic process	Pgr	IEP		Rat	PMID:8344215\|RGD:1601291
Biological Process	GO:0002070	epithelial cell maturation	Pgr	IMP	MGI:MGI:1857933	Mouse	PMID:14765981
Biological Process	GO:0044849	estrous cycle	Pgr	IEP		Rat	PMID:16461543\|RGD:7248717
Biological Process	GO:0060180	female mating behavior	Pgr	IMP		Rat	PMID:19094083\|RGD:7248715
Biological Process	GO:0002071	glandular epithelial cell maturation	Pgr	IMP	MGI:MGI:1857933	Mouse	PMID:14765981
Biological Process	GO:0048286	lung alveolus development	Pgr	IMP	MGI:MGI:3032652	Mouse	PMID:24190884
Biological Process	GO:0001553	luteinization	Pgr	IEP		Rat	PMID:8344215\|RGD:1601291
Biological Process	GO:0042700	luteinizing hormone signaling pathway	pgr	IMP	ZFIN:ZDB-GENO-170907-1	Zfish	PMID:27333837
Biological Process	GO:0030879	mammary gland development	Pgr	IMP	MGI:MGI:2674932	Mouse	PMID:12897242
Biological Process	GO:0030879	mammary gland development	Pgr	IMP	MGI:MGI:1857933	Mouse	PMID:14765981
Biological Process	GO:0043066	negative regulation of apoptotic process	Pgr	IMP		Rat	PMID:22778216\|RGD:7248712
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Pgr	IEP		Rat	PMID:12457039\|RGD:729543
Biological Process	GO:0010629	negative regulation of gene expression	PGR	IEP		Human	PMID:21695196
Biological Process	GO:1904709	negative regulation of granulosa cell apoptotic process	Pgr	IMP		Rat	PMID:19208546\|RGD:10401186
Biological Process	GO:0030728	ovulation	pgr	IMP	ZFIN:ZDB-GENO-150717-3	Zfish	PMID:25852646
Biological Process	GO:0030728	ovulation	pgr	IMP	ZFIN:ZDB-GENO-170907-1	Zfish	PMID:27333837
Biological Process	GO:0030728	ovulation	pgr	IMP	ZFIN:ZDB-GENO-150717-2	Zfish	PMID:25852646
Biological Process	GO:0030728	ovulation	pgr	IMP	ZFIN:ZDB-GENO-150717-4	Zfish	PMID:25852646
Biological Process	GO:0001542	ovulation from ovarian follicle	Pgr	IMP	MGI:MGI:2674932	Mouse	PMID:12897242
Biological Process	GO:0038001	paracrine signaling	Pgr	IMP	MGI:MGI:3032652	Mouse	PMID:24190884
Biological Process	GO:0008284	positive regulation of cell population proliferation	Pgr	IDA		Rat	PMID:16020483\|RGD:7248707
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Pgr	IDA		Rat	PMID:8344215\|RGD:1601291
Biological Process	GO:0014911	positive regulation of smooth muscle cell migration	Pgr	IMP		Rat	PMID:21440892\|RGD:7248703
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	PGR	IDA		Human	PMID:17785366
Biological Process	GO:0050847	progesterone receptor signaling pathway	Pgr	IDA		Mouse	PMID:16176985
Biological Process	GO:0006355	regulation of DNA-templated transcription	Pgr	IMP		Mouse	PMID:14681235
Biological Process	GO:0050678	regulation of epithelial cell proliferation	Pgr	IMP	MGI:MGI:2674932	Mouse	PMID:12897242
Biological Process	GO:0042220	response to cocaine	Pgr	IDA		Rat	PMID:17109827\|RGD:7248706
Biological Process	GO:0043627	response to estrogen	Pgr	IEP		Rat	PMID:22147012\|RGD:7248701
Biological Process	GO:0032570	response to progesterone	Pgr	IEP		Rat	PMID:22147012\|RGD:7248701
Biological Process	GO:0060748	tertiary branching involved in mammary gland duct morphogenesis	Pgr	IMP	MGI:MGI:1857933	Mouse	PMID:10733525

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.