Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PHETA2
  • Mouse genes Pheta2
  • Rat genes Pheta2
  • Zfish genes pheta1,pheta2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pheta2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	PHETA2	IPI	UniProtKB:P32019	Human	PMID:21233288
Molecular Function	GO:0005515	protein binding	PHETA2	IPI	UniProtKB:Q01968	Human	PMID:21233288
Molecular Function	GO:0005515	protein binding	PHETA2	IPI	UniProtKB:Q8N4B1	Human	PMID:21233288
Molecular Function	GO:0005515	protein binding	PHETA2	IPI	UniProtKB:Q01968-2	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	PHETA2	IPI	UniProtKB:Q01968-2	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	PHETA2	IPI	UniProtKB:Q9NW61	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	PHETA2	IPI	UniProtKB:Q01968-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PHETA2	IPI	UniProtKB:Q5SYC1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PHETA2	IPI	UniProtKB:Q8N4B1-4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PHETA2	IPI	UniProtKB:Q9NW61	Human	PMID:32296183
Molecular Function	GO:0042803	protein homodimerization activity	PHETA2	IPI	UniProtKB:Q6ICB4	Human	PMID:21233288
Cellular Component	GO:0030136	clathrin-coated vesicle	PHETA2	IDA		Human	PMID:21233288
Cellular Component	GO:0005769	early endosome	PHETA2	IDA		Human	PMID:21233288
Cellular Component	GO:0055037	recycling endosome	PHETA2	IDA		Human	PMID:21233288
Cellular Component	GO:0005802	trans-Golgi network	PHETA2	IDA		Human	PMID:21233288
Biological Process	GO:0060271	cilium assembly	pheta2	IMP	ZFIN:ZDB-GENO-210727-6	Zfish	PMID:32152089
Biological Process	GO:0060271	cilium assembly	pheta1	IMP	ZFIN:ZDB-GENO-210727-5	Zfish	PMID:32152089
Biological Process	GO:1904888	cranial skeletal system development	pheta1	IMP	ZFIN:ZDB-GENO-210727-5	Zfish	PMID:32152089
Biological Process	GO:1904888	cranial skeletal system development	pheta2	IMP	ZFIN:ZDB-GENO-210727-6	Zfish	PMID:32152089
Biological Process	GO:0007032	endosome organization	PHETA2	IMP		Human	PMID:21233288
Biological Process	GO:0001881	receptor recycling	PHETA2	IMP		Human	PMID:21233288
Biological Process	GO:0030100	regulation of endocytosis	pheta1	IGI	ZFIN:ZDB-GENO-221019-3,ZFIN:ZDB-MRPHLNO-221012-1	Zfish	PMID:34673953
Biological Process	GO:0030100	regulation of endocytosis	pheta1	IMP	ZFIN:ZDB-MRPHLNO-221012-1	Zfish	PMID:34673953
Biological Process	GO:0030100	regulation of endocytosis	pheta1	IGI	ZFIN:ZDB-GENO-221019-1,ZFIN:ZDB-MRPHLNO-120405-1	Zfish	PMID:34673953
Biological Process	GO:0030100	regulation of endocytosis	pheta1	IMP	ZFIN:ZDB-GENO-221019-1	Zfish	PMID:34673953
Biological Process	GO:0042147	retrograde transport, endosome to Golgi	PHETA2	IMP		Human	PMID:21233288

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern