Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PHEX
  • Mouse genes Phex
  • Rat genes Phex
  • Zfish genes phex
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Phex

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	PHEX	IPI	UniProtKB:Q9NQ76	Human	PMID:15664000
Cellular Component	GO:0005783	endoplasmic reticulum	Phex	IDA		Mouse	PMID:11811562
Cellular Component	GO:0005794	Golgi apparatus	Phex	IDA		Mouse	PMID:11811562
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Phex	IDA		Mouse	PMID:11811562
Biological Process	GO:0060348	bone development	Phex	IEP		Rat	PMID:11064151|RGD:11556272
Biological Process	GO:0030282	bone mineralization	Phex	IMP	MGI:MGI:1857312	Mouse	PMID:15843468
Biological Process	GO:0071374	cellular response to parathyroid hormone stimulus	Phex	IEP		Rat	PMID:21826652|RGD:11556255
Biological Process	GO:0071305	cellular response to vitamin D	Phex	IEP		Rat	PMID:15337762|RGD:11556251
Biological Process	GO:0030324	lung development	Phex	IEP		Rat	PMID:11064151|RGD:11556272
Biological Process	GO:0042476	odontogenesis	Phex	IMP	MGI:MGI:1857312	Mouse	PMID:23174213
Biological Process	GO:0019637	organophosphate metabolic process	Phex	IMP	MGI:MGI:1857312	Mouse	PMID:15843468
Biological Process	GO:0006508	proteolysis	PHEX	IDA		Human	PMID:11409890
Biological Process	GO:0060416	response to growth hormone	Phex	IEP		Rat	PMID:11064151|RGD:11556272
Biological Process	GO:1990418	response to insulin-like growth factor stimulus	Phex	IEP		Rat	PMID:11064151|RGD:11556272
Biological Process	GO:1904383	response to sodium phosphate	Phex	IEP		Rat	PMID:11051050|RGD:11556252
Biological Process	GO:0033280	response to vitamin D	Phex	IEP		Rat	PMID:14693675|RGD:11556273

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern