Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PHF12
  • Mouse genes Phf12
  • Rat genes Phf12
  • Zfish genes phf12a,phf12b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Phf12

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0035091	phosphatidylinositol binding	PHF12	IDA		Human	PMID:16893883
Molecular Function	GO:0005515	protein binding	PHF12	IPI	UniProtKB:Q08117	Human	PMID:11390640
Molecular Function	GO:0005515	protein binding	PHF12	IPI	UniProtKB:Q60520	Human	PMID:11390640
Molecular Function	GO:0005515	protein binding	PHF12	IPI	UniProtKB:Q9UBU8-2	Human	PMID:22244764
Molecular Function	GO:0005515	protein binding	PHF12	IPI	UniProtKB:Q9UBU8-2	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	PHF12	IPI	UniProtKB:Q9UBU8-2	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	Phf12	IPI	UniProtKB:Q9UBU8-2	Mouse	MGI:MGI:5918426|PMID:22244764
Molecular Function	GO:0003714	transcription corepressor activity	PHF12	IDA		Human	PMID:22048773
Molecular Function	GO:0001222	transcription corepressor binding	Phf12	IPI	PR:Q60520	Mouse	PMID:11390640
Cellular Component	GO:0005654	nucleoplasm	PHF12	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	PHF12	IDA		Human	PMID:11390640
Cellular Component	GO:0005634	nucleus	PHF12	IDA		Human	PMID:22048773
Cellular Component	GO:0016580	Sin3 complex	PHF12	IDA		Human	PMID:22048773
Cellular Component	GO:0017053	transcription repressor complex	PHF12	IDA		Human	PMID:11390640
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	PHF12	IDA		Human	PMID:11390640
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	PHF12	IDA		Human	PMID:22048773

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern