Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PHF2
  • Mouse genes Phf2
  • Rat genes Phf2
  • Zfish genes phf2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Phf2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0032454	histone H3K9 demethylase activity	PHF2	IDA		Human	PMID:21532585
Molecular Function	GO:0035575	histone H4K20 demethylase activity	Phf2	IMP		Mouse	MGI:MGI:6716956|PMID:22921934
Molecular Function	GO:0005506	iron ion binding	PHF2	IDA		Human	PMID:21167174
Molecular Function	GO:0035064	methylated histone binding	PHF2	IDA		Human	PMID:20129925
Molecular Function	GO:0035064	methylated histone binding	PHF2	IDA		Human	PMID:21167174
Molecular Function	GO:0005515	protein binding	PHF2	IPI	UniProtKB:P41235	Human	PMID:21532585
Molecular Function	GO:0005515	protein binding	PHF2	IPI	UniProtKB:Q14865	Human	PMID:21532585
Molecular Function	GO:0005515	protein binding	PHF2	IPI	UniProtKB:Q96RI1	Human	PMID:21532585
Molecular Function	GO:0005515	protein binding	Phf2	IPI	UniProtKB:Q04207	Mouse	MGI:MGI:6716956|PMID:22921934
Molecular Function	GO:0003713	transcription coactivator activity	PHF2	IDA		Human	PMID:21532585
Molecular Function	GO:0008270	zinc ion binding	PHF2	IDA		Human	PMID:20129925
Cellular Component	GO:0000776	kinetochore	PHF2	IDA		Human	PMID:20813266
Cellular Component	GO:0005730	nucleolus	PHF2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005730	nucleolus	PHF2	IDA		Human	PMID:20129925
Cellular Component	GO:0005654	nucleoplasm	PHF2	IDA		Human	GO_REF:0000052
Biological Process	GO:0061188	negative regulation of rDNA heterochromatin formation	PHF2	IMP		Human	PMID:20129925
Biological Process	GO:0006482	protein demethylation	PHF2	IDA		Human	PMID:21532585
Biological Process	GO:0045815	transcription initiation-coupled chromatin remodeling	Phf2	IMP		Mouse	MGI:MGI:6716956|PMID:22921934

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern