Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PHGDH
  • Mouse genes Phgdh
  • Rat genes Phgdh
  • Zfish genes phgdh
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Phgdh

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004617	phosphoglycerate dehydrogenase activity	Phgdh	IDA		Rat	PMID:9163325|RGD:61693
Cellular Component	GO:0070062	extracellular exosome	PHGDH	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	PHGDH	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	PHGDH	HDA		Human	PMID:20458337
Cellular Component	GO:0070062	extracellular exosome	PHGDH	HDA		Human	PMID:23533145
Cellular Component	GO:0043209	myelin sheath	Phgdh	HDA		Mouse	MGI:MGI:3834050|PMID:17634366
Biological Process	GO:0070314	G1 to G0 transition	Phgdh	IMP	MGI:MGI:3769591	Mouse	PMID:19114063
Biological Process	GO:0009448	gamma-aminobutyric acid metabolic process	Phgdh	IMP	MGI:MGI:3769591	Mouse	PMID:19114063
Biological Process	GO:0021782	glial cell development	Phgdh	IMP	MGI:MGI:3769591	Mouse	PMID:19114063
Biological Process	GO:0006541	glutamine metabolic process	Phgdh	IMP	MGI:MGI:3769591	Mouse	PMID:19114063
Biological Process	GO:0006544	glycine metabolic process	Phgdh	IMP	MGI:MGI:3769591	Mouse	PMID:19114063
Biological Process	GO:0006563	L-serine metabolic process	Phgdh	IMP	MGI:MGI:3769591	Mouse	PMID:19114063
Biological Process	GO:0021915	neural tube development	Phgdh	IMP	MGI:MGI:3769591	Mouse	PMID:19114063
Biological Process	GO:0022008	neurogenesis	Phgdh	IMP	MGI:MGI:3769591	Mouse	PMID:19114063
Biological Process	GO:0031175	neuron projection development	Phgdh	IMP	MGI:MGI:3769591	Mouse	PMID:19114063
Biological Process	GO:0010468	regulation of gene expression	Phgdh	IMP	MGI:MGI:3769591	Mouse	PMID:19114063
Biological Process	GO:0021510	spinal cord development	Phgdh	IMP	MGI:MGI:3769591	Mouse	PMID:19114063
Biological Process	GO:0019530	taurine metabolic process	Phgdh	IMP	MGI:MGI:3769591	Mouse	PMID:19114063
Biological Process	GO:0006566	threonine metabolic process	Phgdh	IMP	MGI:MGI:3769591	Mouse	PMID:19114063

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern