Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PHLDA3
  • Mouse genes Phlda3
  • Rat genes Phlda3
  • Zfish genes phlda3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Phlda3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	PHLDA3	IDA		Human	PMID:19203586
Molecular Function	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	PHLDA3	IDA		Human	PMID:19203586
Molecular Function	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	PHLDA3	IDA		Human	PMID:19203586
Molecular Function	GO:0032266	phosphatidylinositol-3-phosphate binding	PHLDA3	IDA		Human	PMID:19203586
Molecular Function	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	PHLDA3	IDA		Human	PMID:19203586
Molecular Function	GO:0010314	phosphatidylinositol-5-phosphate binding	PHLDA3	IDA		Human	PMID:19203586
Cellular Component	GO:0005886	plasma membrane	PHLDA3	IDA		Human	PMID:19203586
Biological Process	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	PHLDA3	IDA		Human	PMID:19203586
Biological Process	GO:0051898	negative regulation of protein kinase B signaling	PHLDA3	IDA		Human	PMID:19203586
Biological Process	GO:0043065	positive regulation of apoptotic process	PHLDA3	IDA		Human	PMID:19203586

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern