Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PHLDB1
  • Mouse genes Phldb1
  • Rat genes Phldb1
  • Zfish genes phldb1a,phldb1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Phldb1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	PHLDB1	IPI	UniProtKB:P51114	Human	PMID:21653829
Cellular Component	GO:0045180	basal cortex	PHLDB1	IDA		Human	PMID:23940118
Cellular Component	GO:0005829	cytosol	PHLDB1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0045171	intercellular bridge	PHLDB1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	PHLDB1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	PHLDB1	IDA		Human	GO_REF:0000052
Biological Process	GO:1904261	positive regulation of basement membrane assembly involved in embryonic body morphogenesis	PHLDB1	IGI	UniProtKB:Q7Z460|UniProtKB:Q86SQ0	Human	PMID:23940118
Biological Process	GO:1904261	positive regulation of basement membrane assembly involved in embryonic body morphogenesis	PHLDB1	IGI	UniProtKB:Q86SQ0	Human	PMID:23940118
Biological Process	GO:1904261	positive regulation of basement membrane assembly involved in embryonic body morphogenesis	PHLDB1	IMP		Human	PMID:23940118
Biological Process	GO:0010717	regulation of epithelial to mesenchymal transition	PHLDB1	IMP		Human	PMID:23940118
Biological Process	GO:0010470	regulation of gastrulation	PHLDB1	IMP		Human	PMID:23940118
Biological Process	GO:0070507	regulation of microtubule cytoskeleton organization	PHLDB1	IGI	UniProtKB:Q7Z460|UniProtKB:Q86SQ0	Human	PMID:23940118

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern