Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PI4K2A
  • Mouse genes Pi4k2a
  • Rat genes Pi4k2a
  • Zfish genes pi4k2a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pi4k2a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004430	1-phosphatidylinositol 4-kinase activity	PI4K2A	IDA		Human	PMID:11279162
Molecular Function	GO:0004430	1-phosphatidylinositol 4-kinase activity	PI4K2A	IDA		Human	PMID:11923287
Molecular Function	GO:0004430	1-phosphatidylinositol 4-kinase activity	PI4K2A	IDA		Human	PMID:12324459
Molecular Function	GO:0004430	1-phosphatidylinositol 4-kinase activity	Pi4k2a	IDA		Rat	PMID:12646710|RGD:2306405
Molecular Function	GO:0035651	AP-3 adaptor complex binding	PI4K2A	IDA		Human	PMID:21998198
Molecular Function	GO:0005524	ATP binding	PI4K2A	IDA		Human	PMID:24675427
Molecular Function	GO:0005515	protein binding	PI4K2A	IPI	UniProtKB:Q8R015	Human	PMID:21998198
Molecular Function	GO:0005515	protein binding	PI4K2A	IPI	UniProtKB:Q91WZ8	Human	PMID:21998198
Molecular Function	GO:0005515	protein binding	PI4K2A	IPI	UniProtKB:Q96J02	Human	PMID:23146885
Molecular Function	GO:0005515	protein binding	PI4K2A	IPI	UniProtKB:Q12768	Human	PMID:23676666
Molecular Function	GO:0044877	protein-containing complex binding	Pi4k2a	IDA		Rat	PMID:18256276|RGD:2306408
Cellular Component	GO:0031410	cytoplasmic vesicle	Pi4k2a	IDA		Rat	PMID:21998198|RGD:8554550
Cellular Component	GO:0030425	dendrite	Pi4k2a	IDA		Mouse	MGI:MGI:5437407|PMID:21998198
Cellular Component	GO:0031901	early endosome membrane	PI4K2A	IDA		Human	PMID:11923287
Cellular Component	GO:0031901	early endosome membrane	Pi4k2a	IDA		Rat	PMID:18256276|RGD:2306408
Cellular Component	GO:0005768	endosome	Pi4k2a	IDA		Rat	PMID:21998198|RGD:8554550
Cellular Component	GO:0070382	exocytic vesicle	Pi4k2a	IDA		Rat	PMID:17122963|RGD:2306407
Cellular Component	GO:0000139	Golgi membrane	PI4K2A	IDA		Human	PMID:12324459
Cellular Component	GO:0035838	growing cell tip	Pi4k2a	IDA		Rat	PMID:21998198|RGD:8554550
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	Pi4k2a	IDA		Rat	PMID:16760431|RGD:2306406
Cellular Component	GO:0005765	lysosomal membrane	PI4K2A	HDA		Human	PMID:17897319
Cellular Component	GO:0016020	membrane	PI4K2A	HDA		Human	PMID:19946888
Cellular Component	GO:0016020	membrane	PI4K2A	IDA		Human	PMID:24675427
Cellular Component	GO:0045121	membrane raft	PI4K2A	IDA		Human	PMID:11279162
Cellular Component	GO:0045121	membrane raft	Pi4k2a	IDA		Rat	PMID:12215430|RGD:633909
Cellular Component	GO:0005739	mitochondrion	Pi4k2a	IDA		Mouse	MGI:MGI:5437407|PMID:21998198
Cellular Component	GO:0043005	neuron projection	Pi4k2a	IDA		Mouse	MGI:MGI:5437407|PMID:21998198
Cellular Component	GO:0043005	neuron projection	Pi4k2a	IDA		Rat	PMID:21998198|RGD:8554550
Cellular Component	GO:0043025	neuronal cell body	Pi4k2a	IDA		Mouse	MGI:MGI:5437407|PMID:21998198
Cellular Component	GO:0043025	neuronal cell body	Pi4k2a	IDA		Rat	PMID:21998198|RGD:8554550
Cellular Component	GO:0043204	perikaryon	Pi4k2a	IDA		Rat	PMID:12646710|RGD:2306405
Cellular Component	GO:0005886	plasma membrane	PI4K2A	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	PI4K2A	IDA		Human	PMID:11279162
Cellular Component	GO:0005886	plasma membrane	Pi4k2a	IDA		Rat	PMID:16356635|RGD:2304067
Cellular Component	GO:0042734	presynaptic membrane	Pi4k2a	IDA		Mouse	MGI:MGI:5437407|PMID:21998198
Cellular Component	GO:0032991	protein-containing complex	Pi4k2a	IDA		Rat	PMID:18256276|RGD:2306408
Cellular Component	GO:0030672	synaptic vesicle membrane	Pi4k2a	IDA		Rat	PMID:12646710|RGD:2306405
Biological Process	GO:0002561	basophil degranulation	Pi4k2a	IMP		Rat	PMID:17122963|RGD:2306407
Biological Process	GO:0006661	phosphatidylinositol biosynthetic process	PI4K2A	IDA		Human	PMID:11279162
Biological Process	GO:0046854	phosphatidylinositol phosphate biosynthetic process	PI4K2A	IDA		Human	PMID:11923287
Biological Process	GO:0046854	phosphatidylinositol phosphate biosynthetic process	PI4K2A	IDA		Human	PMID:12324459
Biological Process	GO:0046854	phosphatidylinositol phosphate biosynthetic process	PI4K2A	IDA		Human	PMID:25168678

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern