Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PI4KA
  • Mouse genes Pi4ka
  • Rat genes Pi4ka
  • Zfish genes pi4kaa,pi4kab
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pi4ka

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004430	1-phosphatidylinositol 4-kinase activity	Pi4ka	IMP		Mouse	MGI:MGI:5476893|PMID:23229899
Molecular Function	GO:0004430	1-phosphatidylinositol 4-kinase activity	Pi4ka	IDA		Rat	PMID:8662589|RGD:633726
Molecular Function	GO:0045296	cadherin binding	PI4KA	HDA		Human	PMID:25468996
Molecular Function	GO:0016301	kinase activity	PI4KA	IDA		Human	PMID:25327288
Molecular Function	GO:0005515	protein binding	PI4KA	IPI	UniProtKB:P60033	Human	PMID:14676841
Molecular Function	GO:0005515	protein binding	PI4KA	IPI	UniProtKB:P27958:PRO_0000037576	Human	PMID:15607035
Molecular Function	GO:0005515	protein binding	PI4KA	IPI	UniProtKB:Q99IB8:PRO_0000045602	Human	PMID:21238945
Molecular Function	GO:0005515	protein binding	PI4KA	IPI	UniProtKB:P27958:PRO_0000037576	Human	PMID:21297162
Molecular Function	GO:0005515	protein binding	PI4KA	IPI	UniProtKB:Q99IB8:PRO_0000045602	Human	PMID:23675303
Molecular Function	GO:0005515	protein binding	PI4KA	IPI	UniProtKB:Q99IB8:PRO_0000045602	Human	PMID:23935497
Molecular Function	GO:0005515	protein binding	PI4KA	IPI	UniProtKB:Q86TG1	Human	PMID:25608530
Molecular Function	GO:0005515	protein binding	PI4KA	IPI	UniProtKB:Q86TV6	Human	PMID:26571211
Molecular Function	GO:0005515	protein binding	PI4KA	IPI	UniProtKB:Q9BYI3	Human	PMID:26571211
Cellular Component	GO:0005737	cytoplasm	PI4KA	IDA		Human	PMID:23229899
Cellular Component	GO:0070062	extracellular exosome	PI4KA	HDA		Human	PMID:20458337
Cellular Component	GO:0005925	focal adhesion	PI4KA	HDA		Human	PMID:21423176
Cellular Component	GO:0030660	Golgi-associated vesicle membrane	Pi4ka	IDA		Rat	PMID:8662589|RGD:633726
Cellular Component	GO:0016020	membrane	PI4KA	HDA		Human	PMID:19946888
Cellular Component	GO:0005886	plasma membrane	PI4KA	IDA		Human	PMID:23229899
Biological Process	GO:0035118	embryonic pectoral fin morphogenesis	pi4kaa	IMP	ZFIN:ZDB-MRPHLNO-100204-3	Zfish	PMID:19887586
Biological Process	GO:0044788	modulation by host of viral process	PI4KA	IMP		Human	PMID:19376974
Biological Process	GO:0046854	phosphatidylinositol phosphate biosynthetic process	Pi4ka	IMP		Mouse	MGI:MGI:5476893|PMID:23229899
Biological Process	GO:0016310	phosphorylation	PI4KA	IDA		Human	PMID:25327288
Biological Process	GO:0140754	reorganization of cellular membranes to establish viral sites of replication	PI4KA	IMP		Human	PMID:19376974

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern