Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PIAS1
  • Mouse genes Pias1
  • Rat genes Pias1
  • Zfish genes pias1a,pias1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pias1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0140297	DNA-binding transcription factor binding	Pias1	IPI	UniProtKB:P28033	Mouse	MGI:MGI:5619430|PMID:24061474
Molecular Function	GO:0019899	enzyme binding	PIAS1	IPI	UniProtKB:P35520	Human	PMID:17087506
Molecular Function	GO:0005515	protein binding	PIAS1	IPI	UniProtKB:O88508	Human	PMID:14752048
Molecular Function	GO:0005515	protein binding	PIAS1	IPI	UniProtKB:P04637	Human	PMID:15133049
Molecular Function	GO:0005515	protein binding	PIAS1	IPI	UniProtKB:Q8N4C6	Human	PMID:16154161
Molecular Function	GO:0005515	protein binding	PIAS1	IPI	UniProtKB:P52952	Human	PMID:18579533
Molecular Function	GO:0005515	protein binding	PIAS1	IPI	UniProtKB:Q9UKL3	Human	PMID:21338522
Molecular Function	GO:0005515	protein binding	PIAS1	IPI	UniProtKB:P29991:PRO_0000037946	Human	PMID:21911577
Molecular Function	GO:0005515	protein binding	PIAS1	IPI	UniProtKB:Q13330	Human	PMID:21965678
Molecular Function	GO:0005515	protein binding	PIAS1	IPI	UniProtKB:O75626	Human	PMID:22555612
Molecular Function	GO:0005515	protein binding	PIAS1	IPI	UniProtKB:P42858	Human	PMID:23275563
Molecular Function	GO:0005515	protein binding	PIAS1	IPI	UniProtKB:P54253	Human	PMID:23275563
Molecular Function	GO:0005515	protein binding	PIAS1	IPI	UniProtKB:P04637	Human	PMID:25241761
Molecular Function	GO:0005515	protein binding	PIAS1	IPI	UniProtKB:G2XKQ0	Human	PMID:27211601
Molecular Function	GO:0005515	protein binding	PIAS1	IPI	UniProtKB:O75626	Human	PMID:28842558
Molecular Function	GO:0005515	protein binding	PIAS1	IPI	UniProtKB:A0A0S2Z5Q7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PIAS1	IPI	UniProtKB:G5E9A7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PIAS1	IPI	UniProtKB:O00628	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PIAS1	IPI	UniProtKB:O14832	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PIAS1	IPI	UniProtKB:O43464	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PIAS1	IPI	UniProtKB:O43933	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PIAS1	IPI	UniProtKB:O60333-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PIAS1	IPI	UniProtKB:O76024	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PIAS1	IPI	UniProtKB:P01023	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PIAS1	IPI	UniProtKB:P02545	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PIAS1	IPI	UniProtKB:P02545-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PIAS1	IPI	UniProtKB:P04792	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PIAS1	IPI	UniProtKB:P05129	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PIAS1	IPI	UniProtKB:P07686	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PIAS1	IPI	UniProtKB:P19404	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PIAS1	IPI	UniProtKB:P26378-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PIAS1	IPI	UniProtKB:P28358	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PIAS1	IPI	UniProtKB:P28799	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PIAS1	IPI	UniProtKB:P29474	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PIAS1	IPI	UniProtKB:P35240	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PIAS1	IPI	UniProtKB:P35240-4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PIAS1	IPI	UniProtKB:P37840	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PIAS1	IPI	UniProtKB:P41219	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PIAS1	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PIAS1	IPI	UniProtKB:P45381	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PIAS1	IPI	UniProtKB:P48643	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PIAS1	IPI	UniProtKB:P50897	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PIAS1	IPI	UniProtKB:P51608	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PIAS1	IPI	UniProtKB:P54252	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PIAS1	IPI	UniProtKB:P54253	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PIAS1	IPI	UniProtKB:P54577	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PIAS1	IPI	UniProtKB:Q13216-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PIAS1	IPI	UniProtKB:Q16143	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PIAS1	IPI	UniProtKB:Q16595	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PIAS1	IPI	UniProtKB:Q16637	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PIAS1	IPI	UniProtKB:Q53GS7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PIAS1	IPI	UniProtKB:Q6NUL7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PIAS1	IPI	UniProtKB:Q7Z699	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PIAS1	IPI	UniProtKB:Q92870-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PIAS1	IPI	UniProtKB:Q9NUW8	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PIAS1	IPI	UniProtKB:Q9P1N4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PIAS1	IPI	UniProtKB:Q9UBB4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Pias1	IPI	UniProtKB:P29590-12	Mouse	MGI:MGI:5487503|PMID:22406621
Molecular Function	GO:0005515	protein binding	Pias1	IPI	UniProtKB:Q505F1	Mouse	MGI:MGI:5919259|PMID:17187077
Molecular Function	GO:0005515	protein binding	Pias1	IPI	UniProtKB:P37238	Mouse	MGI:MGI:3604169|PMID:16127449
Molecular Function	GO:0005515	protein binding	Pias1	IPI	UniProtKB:Q9Z0P7	Mouse	MGI:MGI:5009176|PMID:14611647
Molecular Function	GO:0005515	protein binding	Pias1	IPI	PR:P29037	Mouse	PMID:16522640
Molecular Function	GO:0005515	protein binding	Pias1	IPI	RGD:3443	Rat	PMID:14500712|RGD:2303123
Molecular Function	GO:0005515	protein binding	Pias1	IPI	RGD:731666	Rat	PMID:16144832|RGD:2303113
Molecular Function	GO:0005515	protein binding	Pias1	IPI	RGD:620218	Rat	PMID:25031400|RGD:10059390
Molecular Function	GO:0019904	protein domain specific binding	Pias1	IPI	RGD:1304676	Rat	PMID:19198660|RGD:5508208
Molecular Function	GO:0019904	protein domain specific binding	Pias1	IDA		Rat	PMID:22406621|RGD:8693410
Molecular Function	GO:0061665	SUMO ligase activity	PIAS1	IDA		Human	PMID:18579533
Molecular Function	GO:0061665	SUMO ligase activity	PIAS1	IDA		Human	PMID:27068747
Molecular Function	GO:0019789	SUMO transferase activity	PIAS1	EXP		Human	PMID:12356736
Molecular Function	GO:0019789	SUMO transferase activity	PIAS1	EXP		Human	PMID:12393906
Molecular Function	GO:0019789	SUMO transferase activity	PIAS1	EXP		Human	PMID:17283066
Molecular Function	GO:0019789	SUMO transferase activity	PIAS1	EXP		Human	PMID:20972456
Molecular Function	GO:0019789	SUMO transferase activity	PIAS1	EXP		Human	PMID:21965678
Molecular Function	GO:0019789	SUMO transferase activity	Pias1	EXP		Mouse	MGI:MGI:6162273|PMID:15123625
Molecular Function	GO:0019789	SUMO transferase activity	Pias1	EXP		Mouse	MGI:MGI:3814507|PMID:18832723
Molecular Function	GO:0019789	SUMO transferase activity	Pias1	EXP		Mouse	MGI:MGI:6162615|PMID:15229330
Molecular Function	GO:0019789	SUMO transferase activity	Pias1	EXP		Mouse	MGI:MGI:6162405|PMID:15507114
Molecular Function	GO:0019789	SUMO transferase activity	Pias1	EXP		Rat	PMID:23118920|RGD:13673818
Molecular Function	GO:0031625	ubiquitin protein ligase binding	Pias1	IPI	UniProtKB:Q8CH72	Mouse	MGI:MGI:5009403|PMID:16816390
Cellular Component	GO:0005634	nucleus	PIAS1	IDA		Human	PMID:14752048
Cellular Component	GO:0005634	nucleus	PIAS1	IDA		Human	PMID:27068747
Cellular Component	GO:0005634	nucleus	Pias1	IDA		Mouse	PMID:16522640
Cellular Component	GO:0005634	nucleus	Pias1	IDA		Rat	PMID:15611122|RGD:2303122
Cellular Component	GO:0016605	PML body	Pias1	IDA		Mouse	MGI:MGI:5487503|PMID:22406621
Biological Process	GO:0045444	fat cell differentiation	Pias1	IDA		Mouse	MGI:MGI:5619430|PMID:24061474
Biological Process	GO:0000082	G1/S transition of mitotic cell cycle	Pias1	IMP		Rat	PMID:20818504|RGD:8693408
Biological Process	GO:0043066	negative regulation of apoptotic process	Pias1	IMP		Rat	PMID:20818504|RGD:8693408
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Pias1	IMP		Mouse	MGI:MGI:3604169|PMID:16127449
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Pias1	IMP		Rat	PMID:16135793|RGD:2303115
Biological Process	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	Pias1	IMP		Mouse	MGI:MGI:5487503|PMID:22406621
Biological Process	GO:0033235	positive regulation of protein sumoylation	PIAS1	IDA		Human	PMID:17696781
Biological Process	GO:0033235	positive regulation of protein sumoylation	PIAS1	IDA		Human	PMID:21965678
Biological Process	GO:0033235	positive regulation of protein sumoylation	Pias1	IMP		Rat	PMID:25031400|RGD:10059390
Biological Process	GO:0051152	positive regulation of smooth muscle cell differentiation	Pias1	IMP		Rat	PMID:16135793|RGD:2303115
Biological Process	GO:0016925	protein sumoylation	PIAS1	IDA		Human	PMID:18579533
Biological Process	GO:0016925	protein sumoylation	Pias1	IDA		Mouse	MGI:MGI:5487503|PMID:22406621
Biological Process	GO:0016925	protein sumoylation	Pias1	IDA		Mouse	MGI:MGI:5619430|PMID:24061474
Biological Process	GO:0065004	protein-DNA complex assembly	Pias1	IMP		Rat	PMID:16135793|RGD:2303115
Biological Process	GO:0042127	regulation of cell population proliferation	Pias1	IMP		Mouse	MGI:MGI:5487503|PMID:22406621
Biological Process	GO:0007283	spermatogenesis	Pias1	IEP		Rat	PMID:12799075|RGD:2303124
Biological Process	GO:0008542	visual learning	Pias1	IMP		Rat	PMID:25031400|RGD:10059390

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern