Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PIAS2
  • Mouse genes Pias2
  • Rat genes Pias2
  • Zfish genes pias2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pias2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	Pias2	IDA		Mouse	PMID:9256341
Molecular Function	GO:0050681	nuclear androgen receptor binding	Pias2	IPI	RGD:2147	Rat	PMID:11117529|RGD:2303126
Molecular Function	GO:0050681	nuclear androgen receptor binding	Pias2	IPI	UniProtKB:P15207	Rat	PMID:9920921|RGD:70792
Molecular Function	GO:0030331	nuclear estrogen receptor binding	Pias2	IPI	RGD:736559|RGD:69213	Rat	PMID:11117529|RGD:2303126
Molecular Function	GO:0035259	nuclear glucocorticoid receptor binding	Pias2	IPI	RGD:732227	Rat	PMID:11117529|RGD:2303126
Molecular Function	GO:0005515	protein binding	PIAS2	IPI	UniProtKB:P10275	Human	PMID:11477070
Molecular Function	GO:0005515	protein binding	PIAS2	IPI	UniProtKB:Q99497	Human	PMID:11477070
Molecular Function	GO:0005515	protein binding	PIAS2	IPI	UniProtKB:O88508	Human	PMID:14752048
Molecular Function	GO:0005515	protein binding	PIAS2	IPI	UniProtKB:Q8N4C6	Human	PMID:16154161
Molecular Function	GO:0005515	protein binding	PIAS2	IPI	UniProtKB:P63279	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	PIAS2	IPI	UniProtKB:Q8IVL1	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	PIAS2	IPI	UniProtKB:P63165	Human	PMID:16204249
Molecular Function	GO:0005515	protein binding	PIAS2	IPI	UniProtKB:P01106	Human	PMID:17418410
Molecular Function	GO:0005515	protein binding	PIAS2	IPI	UniProtKB:P63279	Human	PMID:19549727
Molecular Function	GO:0005515	protein binding	PIAS2	IPI	UniProtKB:P63279	Human	PMID:20936779
Molecular Function	GO:0005515	protein binding	PIAS2	IPI	UniProtKB:Q9BYX4	Human	PMID:21156324
Molecular Function	GO:0005515	protein binding	PIAS2	IPI	UniProtKB:O95273	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	PIAS2	IPI	UniProtKB:P63165	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	PIAS2	IPI	UniProtKB:P63279	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	PIAS2	IPI	UniProtKB:Q96T51	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	PIAS2	IPI	UniProtKB:P63244	Human	PMID:22210188
Molecular Function	GO:0005515	protein binding	PIAS2	IPI	UniProtKB:P29590-12	Human	PMID:22406621
Molecular Function	GO:0005515	protein binding	PIAS2	IPI	UniProtKB:G2XKQ0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PIAS2	IPI	UniProtKB:O43741	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PIAS2	IPI	UniProtKB:O95273	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PIAS2	IPI	UniProtKB:O96006	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PIAS2	IPI	UniProtKB:P14136	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PIAS2	IPI	UniProtKB:P20592	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PIAS2	IPI	UniProtKB:P36406	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PIAS2	IPI	UniProtKB:P63165	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PIAS2	IPI	UniProtKB:P63279	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PIAS2	IPI	UniProtKB:Q08379	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PIAS2	IPI	UniProtKB:Q59GP6	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PIAS2	IPI	UniProtKB:Q7KZS0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PIAS2	IPI	UniProtKB:Q8IVL1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PIAS2	IPI	UniProtKB:Q8TD31-3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PIAS2	IPI	UniProtKB:Q969E8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PIAS2	IPI	UniProtKB:Q96BR9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PIAS2	IPI	UniProtKB:Q96HD9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PIAS2	IPI	UniProtKB:O75626	Human	PMID:28842558
Molecular Function	GO:0005515	protein binding	Pias2	IPI	PR:P29037	Mouse	PMID:16522640
Molecular Function	GO:0005515	protein binding	Pias2	IPI	RGD:731666	Rat	PMID:16144832|RGD:2303113
Molecular Function	GO:0019904	protein domain specific binding	Pias2	IPI	RGD:1304676	Rat	PMID:19198660|RGD:5508208
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	PIAS2	IPI	UniProtKB:O35426-1	Human	PMID:20408817
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	PIAS2	IPI	UniProtKB:O35426-2	Human	PMID:20408817
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	Pias2	IPI	UniProtKB:O35426-1|UniProtKB:O35426-2	Mouse	MGI:MGI:5616311|PMID:20408817
Molecular Function	GO:0061665	SUMO ligase activity	PIAS2	IDA		Human	PMID:18579533
Molecular Function	GO:0019789	SUMO transferase activity	PIAS2	EXP		Human	PMID:12393906
Molecular Function	GO:0019789	SUMO transferase activity	PIAS2	EXP		Human	PMID:17283066
Molecular Function	GO:0019789	SUMO transferase activity	PIAS2	EXP		Human	PMID:18628979
Molecular Function	GO:0019789	SUMO transferase activity	PIAS2	EXP		Human	PMID:19041634
Molecular Function	GO:0019789	SUMO transferase activity	PIAS2	EXP		Human	PMID:20972456
Molecular Function	GO:0019789	SUMO transferase activity	PIAS2	EXP		Human	PMID:23145142
Molecular Function	GO:0019789	SUMO transferase activity	Pias2	EXP		Mouse	MGI:MGI:6162273|PMID:15123625
Molecular Function	GO:0019789	SUMO transferase activity	Pias2	EXP		Mouse	MGI:MGI:6162405|PMID:15507114
Molecular Function	GO:0019789	SUMO transferase activity	Pias2	EXP		Mouse	MGI:MGI:3814507|PMID:18832723
Molecular Function	GO:0019789	SUMO transferase activity	Pias2	EXP		Mouse	MGI:MGI:6162615|PMID:15229330
Molecular Function	GO:0019789	SUMO transferase activity	Pias2	IDA		Mouse	PMID:15767674
Molecular Function	GO:0031625	ubiquitin protein ligase binding	Pias2	IPI	UniProtKB:Q8CH72	Mouse	MGI:MGI:5009403|PMID:16816390
Cellular Component	GO:0005654	nucleoplasm	PIAS2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	PIAS2	IDA		Human	PMID:11477070
Cellular Component	GO:0005634	nucleus	PIAS2	IDA		Human	PMID:14752048
Cellular Component	GO:0005634	nucleus	PIAS2	HDA		Human	PMID:21630459
Cellular Component	GO:0005634	nucleus	Pias2	IDA		Mouse	PMID:16522640
Cellular Component	GO:0005634	nucleus	Pias2	IDA		Rat	PMID:12799075|RGD:2303124
Cellular Component	GO:0005634	nucleus	Pias2	IDA		Rat	PMID:9920921|RGD:70792
Cellular Component	GO:0016605	PML body	PIAS2	IDA		Human	PMID:22406621
Biological Process	GO:0030521	androgen receptor signaling pathway	Pias2	IMP		Rat	PMID:9920921|RGD:70792
Biological Process	GO:0006351	DNA-templated transcription	Pias2	IDA		Mouse	PMID:9256341
Biological Process	GO:0060766	negative regulation of androgen receptor signaling pathway	PIAS2	IDA		Human	PMID:11477070
Biological Process	GO:0050775	positive regulation of dendrite morphogenesis	Pias2	IMP		Rat	PMID:17855618|RGD:2298751
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Pias2	IMP		Rat	PMID:9920921|RGD:70792
Biological Process	GO:0016925	protein sumoylation	PIAS2	IDA		Human	PMID:22406621
Biological Process	GO:0016925	protein sumoylation	Pias2	IDA		Mouse	PMID:15767674
Biological Process	GO:0060765	regulation of androgen receptor signaling pathway	Pias2	IDA		Rat	PMID:9920921|RGD:70792
Biological Process	GO:0006355	regulation of DNA-templated transcription	Pias2	IDA		Rat	PMID:11117529|RGD:2303126
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	Pias2	IDA		Mouse	PMID:9256341
Biological Process	GO:0010033	response to organic substance	Pias2	IEP		Rat	PMID:12799075|RGD:2303124
Biological Process	GO:0033574	response to testosterone	Pias2	IEP		Rat	PMID:12799075|RGD:2303124
Biological Process	GO:0007283	spermatogenesis	Pias2	IEP		Rat	PMID:12799075|RGD:2303124

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern