Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PIF1
  • Mouse genes Pif1
  • Rat genes Pif1
  • Zfish genes pif1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pif1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0043139	5'-3' DNA helicase activity	PIF1	IDA		Human	PMID:16522649
Molecular Function	GO:0033678	5'-3' DNA/RNA helicase activity	PIF1	IDA		Human	PMID:16522649
Molecular Function	GO:0005524	ATP binding	PIF1	IDA		Human	PMID:16522649
Molecular Function	GO:0000287	magnesium ion binding	PIF1	IDA		Human	PMID:16522649
Molecular Function	GO:0017116	single-stranded DNA helicase activity	PIF1	IDA		Human	PMID:16522649
Molecular Function	GO:0042162	telomeric DNA binding	PIF1	IDA		Human	PMID:16522649
Cellular Component	GO:0000781	chromosome, telomeric region	PIF1	IDA		Human	PMID:16522649
Biological Process	GO:0051974	negative regulation of telomerase activity	PIF1	IDA		Human	PMID:16522649
Biological Process	GO:0032211	negative regulation of telomere maintenance via telomerase	PIF1	IDA		Human	PMID:23657261
Biological Process	GO:0032204	regulation of telomere maintenance	PIF1	IDA		Human	PMID:16522649

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern