Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PIK3C3
  • Mouse genes Pik3c3
  • Rat genes Pik3c3
  • Zfish genes pik3c3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pik3c3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016303	1-phosphatidylinositol-3-kinase activity	PIK3C3	IMP		Human	PMID:20208530
Molecular Function	GO:0016303	1-phosphatidylinositol-3-kinase activity	Pik3c3	IDA		Rat	PMID:12244116|RGD:633560
Molecular Function	GO:0016301	kinase activity	PIK3C3	IDA		Human	PMID:25327288
Molecular Function	GO:0035004	phosphatidylinositol 3-kinase activity	Pik3c3	IMP		Rat	PMID:11171063|RGD:628447
Molecular Function	GO:0052742	phosphatidylinositol kinase activity	PIK3C3	IDA		Human	PMID:7628435
Molecular Function	GO:0005515	protein binding	PIK3C3	IPI	UniProtKB:P51149	Human	PMID:14617358
Molecular Function	GO:0005515	protein binding	PIK3C3	IPI	UniProtKB:P55160	Human	PMID:16417406
Molecular Function	GO:0005515	protein binding	PIK3C3	IPI	UniProtKB:Q14457	Human	PMID:19050071
Molecular Function	GO:0005515	protein binding	PIK3C3	IPI	UniProtKB:Q6ZNE5	Human	PMID:19050071
Molecular Function	GO:0005515	protein binding	PIK3C3	IPI	UniProtKB:Q14457	Human	PMID:19270696
Molecular Function	GO:0005515	protein binding	PIK3C3	IPI	UniProtKB:Q6ZNE5	Human	PMID:19270696
Molecular Function	GO:0005515	protein binding	PIK3C3	IPI	UniProtKB:Q92622	Human	PMID:19270696
Molecular Function	GO:0005515	protein binding	PIK3C3	IPI	UniProtKB:Q9P2Y5	Human	PMID:19270696
Molecular Function	GO:0005515	protein binding	PIK3C3	IPI	UniProtKB:Q17UT5	Human	PMID:20142477
Molecular Function	GO:0005515	protein binding	PIK3C3	IPI	UniProtKB:Q14457	Human	PMID:20562859
Molecular Function	GO:0005515	protein binding	PIK3C3	IPI	UniProtKB:Q6ZNE5	Human	PMID:20562859
Molecular Function	GO:0005515	protein binding	PIK3C3	IPI	UniProtKB:Q92622	Human	PMID:20562859
Molecular Function	GO:0005515	protein binding	PIK3C3	IPI	UniProtKB:Q96F24	Human	PMID:20562859
Molecular Function	GO:0005515	protein binding	PIK3C3	IPI	UniProtKB:Q9P2Y5	Human	PMID:20562859
Molecular Function	GO:0005515	protein binding	PIK3C3	IPI	UniProtKB:Q92622	Human	PMID:21062745
Molecular Function	GO:0005515	protein binding	PIK3C3	IPI	UniProtKB:Q14457	Human	PMID:22095288
Molecular Function	GO:0005515	protein binding	PIK3C3	IPI	UniProtKB:Q15139	Human	PMID:22095288
Molecular Function	GO:0005515	protein binding	PIK3C3	IPI	UniProtKB:Q6ZNE5	Human	PMID:22493499
Molecular Function	GO:0005515	protein binding	PIK3C3	IPI	UniProtKB:Q9P2Y5	Human	PMID:22493499
Molecular Function	GO:0005515	protein binding	PIK3C3	IPI	UniProtKB:Q14457	Human	PMID:23316280
Molecular Function	GO:0005515	protein binding	PIK3C3	IPI	UniProtKB:Q14457	Human	PMID:23332761
Molecular Function	GO:0005515	protein binding	PIK3C3	IPI	UniProtKB:Q6ZNE5	Human	PMID:23332761
Molecular Function	GO:0005515	protein binding	PIK3C3	IPI	UniProtKB:Q14457	Human	PMID:23364696
Molecular Function	GO:0005515	protein binding	PIK3C3	IPI	UniProtKB:Q14457	Human	PMID:23878393
Molecular Function	GO:0005515	protein binding	PIK3C3	IPI	UniProtKB:A8MW95	Human	PMID:23954414
Molecular Function	GO:0005515	protein binding	PIK3C3	IPI	UniProtKB:Q14457	Human	PMID:23954414
Molecular Function	GO:0005515	protein binding	PIK3C3	IPI	UniProtKB:Q14457	Human	PMID:24034250
Molecular Function	GO:0005515	protein binding	PIK3C3	IPI	UniProtKB:Q14457	Human	PMID:24056303
Molecular Function	GO:0005515	protein binding	PIK3C3	IPI	UniProtKB:Q9P2Y5	Human	PMID:24056303
Molecular Function	GO:0005515	protein binding	PIK3C3	IPI	UniProtKB:Q14457	Human	PMID:24472739
Molecular Function	GO:0005515	protein binding	PIK3C3	IPI	UniProtKB:Q14457	Human	PMID:24785657
Molecular Function	GO:0005515	protein binding	PIK3C3	IPI	UniProtKB:Q6ZNE5	Human	PMID:24785657
Molecular Function	GO:0005515	protein binding	PIK3C3	IPI	UniProtKB:Q96F24	Human	PMID:24785657
Molecular Function	GO:0005515	protein binding	PIK3C3	IPI	UniProtKB:Q9P2Y5	Human	PMID:24785657
Molecular Function	GO:0005515	protein binding	PIK3C3	IPI	UniProtKB:Q96F24	Human	PMID:24849286
Molecular Function	GO:0005515	protein binding	PIK3C3	IPI	UniProtKB:Q9P2Y5	Human	PMID:24849286
Molecular Function	GO:0005515	protein binding	PIK3C3	IPI	UniProtKB:Q14457	Human	PMID:25490155
Molecular Function	GO:0005515	protein binding	PIK3C3	IPI	UniProtKB:Q6ZNE5	Human	PMID:25490155
Molecular Function	GO:0005515	protein binding	PIK3C3	IPI	UniProtKB:Q9P2Y5	Human	PMID:25490155
Molecular Function	GO:0005515	protein binding	PIK3C3	IPI	UniProtKB:Q14457	Human	PMID:25594178
Molecular Function	GO:0005515	protein binding	PIK3C3	IPI	UniProtKB:Q14457	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	PIK3C3	IPI	UniProtKB:Q14457	Human	PMID:26783301
Molecular Function	GO:0005515	protein binding	PIK3C3	IPI	UniProtKB:Q14457	Human	PMID:28479384
Molecular Function	GO:0005515	protein binding	PIK3C3	IPI	UniProtKB:Q6ZNE5	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	PIK3C3	IPI	UniProtKB:Q96F24	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	PIK3C3	IPI	UniProtKB:P0DP23	Human	PMID:28890335
Molecular Function	GO:0005515	protein binding	PIK3C3	IPI	UniProtKB:Q6ZNE5	Human	PMID:31806350
Molecular Function	GO:0005515	protein binding	PIK3C3	IPI	UniProtKB:Q14457	Human	PMID:33422265
Molecular Function	GO:0005515	protein binding	PIK3C3	IPI	UniProtKB:Q6ZNE5	Human	PMID:33422265
Molecular Function	GO:0005515	protein binding	PIK3C3	IPI	UniProtKB:Q8NEB9	Human	PMID:33473107
Molecular Function	GO:0005515	protein binding	PIK3C3	IPI	UniProtKB:Q9P2Y5	Human	PMID:34386498
Molecular Function	GO:0005515	protein binding	PIK3C3	IPI	UniProtKB:P06239	Human	PMID:7504174
Molecular Function	GO:0005515	protein binding	Pik3c3	IPI	UniProtKB:P23242	Mouse	MGI:MGI:5915435|PMID:24705551
Molecular Function	GO:0005515	protein binding	Pik3c3	IPI	UniProtKB:O88597	Mouse	MGI:MGI:5619439|PMID:23332761
Molecular Function	GO:0005515	protein binding	Pik3c3	IPI	UniProtKB:O88597	Mouse	MGI:MGI:5519172|PMID:23974797
Molecular Function	GO:0005515	protein binding	Pik3c3	IPI	UniProtKB:O88597	Mouse	MGI:MGI:5634877|PMID:24849286
Molecular Function	GO:0005515	protein binding	Pik3c3	IPI	PR:O88597	Mouse	PMID:27994061
Molecular Function	GO:0005515	protein binding	Pik3c3	IPI	PR:Q9QUM4	Mouse	PMID:22493499
Molecular Function	GO:0005515	protein binding	Pik3c3	IPI	RGD:1323457	Rat	PMID:11171063|RGD:628447
Molecular Function	GO:0004672	protein kinase activity	Pik3c3	IMP		Mouse	PMID:15010863
Cellular Component	GO:0044754	autolysosome	PIK3C3	IDA		Human	PMID:25327288
Cellular Component	GO:0005770	late endosome	PIK3C3	IDA		Human	PMID:14617358
Cellular Component	GO:0016020	membrane	PIK3C3	HDA		Human	PMID:19946888
Cellular Component	GO:0030496	midbody	PIK3C3	IDA		Human	PMID:20208530
Cellular Component	GO:0045335	phagocytic vesicle	Pik3c3	IDA		Mouse	PMID:22493499
Cellular Component	GO:0035032	phosphatidylinositol 3-kinase complex, class III	PIK3C3	IPI		Human	PMID:25490155
Cellular Component	GO:0035032	phosphatidylinositol 3-kinase complex, class III	Pik3c3	IDA		Mouse	MGI:MGI:5619439|PMID:23332761
Biological Process	GO:0000045	autophagosome assembly	PIK3C3	IDA		Human	PMID:33637724
Biological Process	GO:0000045	autophagosome assembly	Pik3c3	IMP		Mouse	PMID:24098492
Biological Process	GO:0000045	autophagosome assembly	Pik3c3	IMP		Rat	PMID:12453151|RGD:2303129
Biological Process	GO:0097352	autophagosome maturation	PIK3C3	IDA		Human	PMID:10625637
Biological Process	GO:0006914	autophagy	PIK3C3	IMP		Human	PMID:25327288
Biological Process	GO:0042149	cellular response to glucose starvation	Pik3c3	IDA		Mouse	MGI:MGI:5619439|PMID:23332761
Biological Process	GO:0009267	cellular response to starvation	Pik3c3	IMP		Mouse	PMID:24098492
Biological Process	GO:0045022	early endosome to late endosome transport	PIK3C3	IDA		Human	PMID:14617358
Biological Process	GO:0045022	early endosome to late endosome transport	PIK3C3	IMP		Human	PMID:14617358
Biological Process	GO:0007032	endosome organization	Pik3c3	IMP		Rat	PMID:12453151|RGD:2303129
Biological Process	GO:0016236	macroautophagy	Pik3c3	IMP		Mouse	MGI:MGI:5630037|PMID:25578879
Biological Process	GO:0016236	macroautophagy	Pik3c3	IMP		Mouse	MGI:MGI:5619439|PMID:23332761
Biological Process	GO:0046854	phosphatidylinositol phosphate biosynthetic process	PIK3C3	IDA		Human	PMID:7628435
Biological Process	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process	PIK3C3	IDA		Human	PMID:8999962
Biological Process	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process	Pik3c3	IMP		Mouse	PMID:24098492
Biological Process	GO:0048015	phosphatidylinositol-mediated signaling	Pik3c3	IDA		Rat	PMID:12244116|RGD:633560
Biological Process	GO:0044829	positive regulation by host of viral genome replication	PIK3C3	IDA		Human	PMID:34320401
Biological Process	GO:0006497	protein lipidation	PIK3C3	IMP		Human	PMID:25327288
Biological Process	GO:0034497	protein localization to phagophore assembly site	Pik3c3	IMP		Mouse	PMID:24098492
Biological Process	GO:0006468	protein phosphorylation	PIK3C3	IDA		Human	PMID:8999962
Biological Process	GO:0006468	protein phosphorylation	Pik3c3	IMP		Mouse	PMID:15010863
Biological Process	GO:0016485	protein processing	Pik3c3	IMP		Rat	PMID:11171063|RGD:628447
Biological Process	GO:0010506	regulation of autophagy	PIK3C3	IDA		Human	PMID:16799551
Biological Process	GO:0032465	regulation of cytokinesis	PIK3C3	IMP		Human	PMID:20208530
Biological Process	GO:0032465	regulation of cytokinesis	PIK3C3	IMP		Human	PMID:20643123
Biological Process	GO:0016241	regulation of macroautophagy	PIK3C3	IDA		Human	PMID:10625637
Biological Process	GO:0050708	regulation of protein secretion	Pik3c3	IMP		Rat	PMID:11171063|RGD:628447
Biological Process	GO:0043201	response to leucine	Pik3c3	IEP		Rat	PMID:19015198|RGD:2303128

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern