Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PIK3R3
  • Mouse genes Pik3r3
  • Rat genes Pik3r3
  • Zfish genes pik3r3a,pik3r3b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pik3r3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity	Pik3r3	IDA		Mouse	PMID:7542745
Molecular Function	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity	Pik3r3	IDA		Rat	PMID:8621382|RGD:68289
Molecular Function	GO:0001784	phosphotyrosine residue binding	PIK3R3	IPI	UniProtKB:Q6GX35	Human	PMID:20624904
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:P00533	Human	PMID:16273093
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:P04626	Human	PMID:16273093
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:P21860	Human	PMID:16273093
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:P42858	Human	PMID:17500595
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:P46108	Human	PMID:19380743
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:Q8IZP0	Human	PMID:20598684
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:P62993	Human	PMID:21706016
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:P12931	Human	PMID:22402981
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:P42336	Human	PMID:22402981
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:P42338	Human	PMID:22402981
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:Q05397	Human	PMID:22402981
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:P21860	Human	PMID:24189400
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:P00533	Human	PMID:24658140
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:P08581	Human	PMID:24728074
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:P10275	Human	PMID:24728074
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:P10721	Human	PMID:24728074
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:Q13480	Human	PMID:24728074
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:P00533	Human	PMID:25241761
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:O43559	Human	PMID:25814554
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:O60237-2	Human	PMID:25814554
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:O60636	Human	PMID:25814554
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:P08631-2	Human	PMID:25814554
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:P12931	Human	PMID:25814554
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:P22681	Human	PMID:25814554
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:P35568	Human	PMID:25814554
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:P42336	Human	PMID:25814554
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:P42338	Human	PMID:25814554
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:P46108	Human	PMID:25814554
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:P53672	Human	PMID:25814554
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:Q05397	Human	PMID:25814554
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:Q5SXH7-1	Human	PMID:25814554
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:Q66PJ3-4	Human	PMID:25814554
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:Q6GQQ9	Human	PMID:25814554
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:Q8IZQ1	Human	PMID:25814554
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:Q8N2H9	Human	PMID:25814554
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:Q8N6F8	Human	PMID:25814554
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:Q8TAK6	Human	PMID:25814554
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:Q8WXH5	Human	PMID:25814554
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:Q96LK0	Human	PMID:25814554
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:Q96R05	Human	PMID:25814554
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:Q99619	Human	PMID:25814554
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:Q9NP31	Human	PMID:25814554
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:Q9NPB6-2	Human	PMID:25814554
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:P42336	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:O00329	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:P42336	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:P42338	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:Q14919	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:P00533	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:A0A1B0GWI1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:A8MTA8-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:I6L996	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:O00329	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:O76041	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:P07947	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:P19237	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:P28838	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:P31321	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:P51451	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:P51692	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:P62993	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:Q07912-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:Q13352	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:Q14140	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:Q14511-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:Q14919	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:Q15742	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:Q3SXR2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:Q4LE39-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:Q5VWN6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:Q6WN34-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:Q6ZNG0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:Q6ZU52	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:Q8N998	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:Q8NCR6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:Q8TC99	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:Q96JM7-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:Q96LK0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:Q96LK8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:Q99592	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:Q9BQD7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:Q9BVN2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:Q9BWG4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:Q9BYU1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:Q9H0I2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:Q9H2G9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:Q9H8W4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:Q9NRI5-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:Q9UL19	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:P04637	Human	PMID:32606738
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:P42336	Human	PMID:34591612
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:P46108	Human	PMID:35044719
Molecular Function	GO:0005515	protein binding	PIK3R3	IPI	UniProtKB:P04626	Human	PMID:35384245
Molecular Function	GO:0005515	protein binding	Pik3r3	IPI	PR:P42337	Mouse	PMID:7542745
Cellular Component	GO:0005942	phosphatidylinositol 3-kinase complex	Pik3r3	IPI	PR:P42337	Mouse	PMID:7542745
Biological Process	GO:0002042	cell migration involved in sprouting angiogenesis	PIK3R3	IGI	UniProtKB:P31749,UniProtKB:Q96IZ2	Human	PMID:28341552
Biological Process	GO:0008286	insulin receptor signaling pathway	Pik3r3	IDA		Mouse	PMID:7542745
Biological Process	GO:0010628	positive regulation of gene expression	PIK3R3	IMP		Human	PMID:28341552
Biological Process	GO:0001934	positive regulation of protein phosphorylation	PIK3R3	IMP		Human	PMID:28341552
Biological Process	GO:0043491	protein kinase B signaling	PIK3R3	IMP		Human	PMID:28341552

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern