Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PIM1
  • Mouse genes Pim1
  • Rat genes Pim1
  • Zfish genes pim1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pim1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005524	ATP binding	PIM1	IDA		Human	PMID:1825810
Molecular Function	GO:0005524	ATP binding	Pim1	IDA		Mouse	MGI:MGI:3687443|PMID:1825810
Molecular Function	GO:0030145	manganese ion binding	PIM1	IDA		Human	PMID:1825810
Molecular Function	GO:0030145	manganese ion binding	Pim1	IDA		Mouse	MGI:MGI:3687443|PMID:1825810
Molecular Function	GO:0005515	protein binding	PIM1	IPI	UniProtKB:P51813	Human	PMID:16186805
Molecular Function	GO:0005515	protein binding	PIM1	IPI	UniProtKB:P39019	Human	PMID:16266891
Molecular Function	GO:0005515	protein binding	PIM1	IPI	UniProtKB:P07954	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PIM1	IPI	UniProtKB:P0C1Z6-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PIM1	IPI	UniProtKB:P51116	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PIM1	IPI	UniProtKB:Q5T203	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PIM1	IPI	UniProtKB:Q8N7W2-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PIM1	IPI	UniProtKB:Q8N9N5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PIM1	IPI	UniProtKB:Q96MH2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PIM1	IPI	UniProtKB:Q9Y2K1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	Pim1	IPI	UniProtKB:P01108	Mouse	MGI:MGI:5294288|PMID:18438430
Molecular Function	GO:0004674	protein serine/threonine kinase activity	PIM1	IDA		Human	PMID:18056989
Molecular Function	GO:0004674	protein serine/threonine kinase activity	PIM1	IDA		Human	PMID:1825810
Molecular Function	GO:0004674	protein serine/threonine kinase activity	Pim1	IDA		Mouse	MGI:MGI:3687443|PMID:1825810
Molecular Function	GO:0004674	protein serine/threonine kinase activity	Pim1	IDA		Mouse	MGI:MGI:5294288|PMID:18438430
Molecular Function	GO:0043024	ribosomal small subunit binding	PIM1	IPI	UniProtKB:P39019	Human	PMID:16266891
Molecular Function	GO:0008134	transcription factor binding	PIM1	IPI	UniProtKB:O43524	Human	PMID:18593906
Cellular Component	GO:0005737	cytoplasm	PIM1	IDA		Human	PMID:1825810
Cellular Component	GO:0005737	cytoplasm	PIM1	IDA		Human	PMID:21474815
Cellular Component	GO:0005829	cytosol	PIM1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005730	nucleolus	PIM1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	PIM1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	PIM1	IDA		Human	PMID:21474815
Biological Process	GO:0048593	camera-type eye morphogenesis	pim1	IMP	ZFIN:ZDB-MRPHLNO-130214-1,ZFIN:ZDB-MRPHLNO-130214-2	Zfish	PMID:23300608
Biological Process	GO:1990748	cellular detoxification	PIM1	IMP		Human	PMID:18056989
Biological Process	GO:0043066	negative regulation of apoptotic process	PIM1	IDA		Human	PMID:16186805
Biological Process	GO:0043433	negative regulation of DNA-binding transcription factor activity	PIM1	IDA		Human	PMID:18593906
Biological Process	GO:0007634	optokinetic behavior	pim1	IMP	ZFIN:ZDB-MRPHLNO-130214-1,ZFIN:ZDB-MRPHLNO-130214-2	Zfish	PMID:23300608
Biological Process	GO:0090336	positive regulation of brown fat cell differentiation	Pim1	IMP		Mouse	MGI:MGI:5812817|PMID:27923061
Biological Process	GO:0060045	positive regulation of cardiac muscle cell proliferation	PIM1	IDA		Human	PMID:21474815
Biological Process	GO:1905062	positive regulation of cardioblast proliferation	PIM1	IDA		Human	PMID:21474815
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Pim1	IMP		Mouse	MGI:MGI:5294288|PMID:18438430
Biological Process	GO:0046777	protein autophosphorylation	PIM1	IDA		Human	PMID:16266891
Biological Process	GO:0006468	protein phosphorylation	PIM1	IDA		Human	PMID:16266891
Biological Process	GO:0006468	protein phosphorylation	PIM1	IDA		Human	PMID:18056989
Biological Process	GO:0006468	protein phosphorylation	PIM1	IDA		Human	PMID:1825810
Biological Process	GO:0006468	protein phosphorylation	Pim1	IDA		Mouse	MGI:MGI:3687443|PMID:1825810
Biological Process	GO:0050821	protein stabilization	Pim1	IDA		Mouse	MGI:MGI:5294288|PMID:18438430
Biological Process	GO:1902033	regulation of hematopoietic stem cell proliferation	Pim1	IDA		Mouse	MGI:MGI:5490148|PMID:23495171
Biological Process	GO:0022898	regulation of transmembrane transporter activity	PIM1	IMP		Human	PMID:18056989
Biological Process	GO:0070561	vitamin D receptor signaling pathway	PIM1	IMP		Human	PMID:22720752

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern