Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PINX1
  • Mouse genes Pinx1
  • Rat genes Pinx1
  • Zfish genes pinx1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pinx1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	PINX1	IPI	UniProtKB:O14746	Human	PMID:11701125
Molecular Function	GO:0005515	protein binding	PINX1	IPI	UniProtKB:P54274-2	Human	PMID:11701125
Molecular Function	GO:0005515	protein binding	PINX1	IPI	UniProtKB:Q96EZ8-2	Human	PMID:15044100
Molecular Function	GO:0005515	protein binding	PINX1	IPI	UniProtKB:O14746	Human	PMID:15381700
Molecular Function	GO:0005515	protein binding	PINX1	IPI	UniProtKB:P54274	Human	PMID:17389648
Molecular Function	GO:0005515	protein binding	PINX1	IPI	UniProtKB:Q9UBB9	Human	PMID:17389648
Molecular Function	GO:0005515	protein binding	PINX1	IPI	UniProtKB:P54274	Human	PMID:18202258
Molecular Function	GO:0005515	protein binding	PINX1	IPI	UniProtKB:P54274	Human	PMID:19265708
Molecular Function	GO:0005515	protein binding	PINX1	IPI	UniProtKB:P19338	Human	PMID:19393617
Molecular Function	GO:0005515	protein binding	PINX1	IPI	UniProtKB:P54274	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	PINX1	IPI	UniProtKB:O14746	Human	PMID:21119197
Molecular Function	GO:0005515	protein binding	PINX1	IPI	UniProtKB:P54274-2	Human	PMID:21119197
Molecular Function	GO:0005515	protein binding	PINX1	IPI	UniProtKB:Q96BJ3	Human	PMID:21900206
Molecular Function	GO:0005515	protein binding	PINX1	IPI	UniProtKB:P54274	Human	PMID:24415760
Molecular Function	GO:0005515	protein binding	PINX1	IPI	UniProtKB:P54274	Human	PMID:27214791
Molecular Function	GO:0005515	protein binding	PINX1	IPI	UniProtKB:O14746	Human	PMID:28255170
Molecular Function	GO:0005515	protein binding	PINX1	IPI	UniProtKB:P06748	Human	PMID:28255170
Molecular Function	GO:0005515	protein binding	PINX1	IPI	UniProtKB:O14787-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PINX1	IPI	UniProtKB:P13807	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PINX1	IPI	UniProtKB:P55081	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PINX1	IPI	UniProtKB:Q8N9N8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PINX1	IPI	UniProtKB:Q96BJ3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PINX1	IPI	UniProtKB:Q9BZL1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PINX1	IPI	UniProtKB:Q9NWQ9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PINX1	IPI	UniProtKB:Q9UKI8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	pinx1	IPI	UniProtKB:A2THE9	Zfish	PMID:18583067
Molecular Function	GO:0044877	protein-containing complex binding	PINX1	IPI	ComplexPortal:CPX-152	Human	PMID:18202258
Molecular Function	GO:0010521	telomerase inhibitor activity	PINX1	IDA		Human	PMID:11701125
Molecular Function	GO:0010521	telomerase inhibitor activity	PINX1	IMP		Human	PMID:11701125
Molecular Function	GO:0010521	telomerase inhibitor activity	PINX1	IMP		Human	PMID:21119197
Molecular Function	GO:0010521	telomerase inhibitor activity	pinx1	IDA		Zfish	PMID:18583067
Molecular Function	GO:0070034	telomerase RNA binding	PINX1	IDA		Human	PMID:15381700
Cellular Component	GO:0000781	chromosome, telomeric region	PINX1	IDA		Human	PMID:11701125
Cellular Component	GO:0000781	chromosome, telomeric region	PINX1	IDA		Human	PMID:19265708
Cellular Component	GO:0000781	chromosome, telomeric region	PINX1	IDA		Human	PMID:21119197
Cellular Component	GO:0000781	chromosome, telomeric region	PINX1	IDA		Human	PMID:24415760
Cellular Component	GO:0000776	kinetochore	PINX1	IDA		Human	PMID:19393617
Cellular Component	GO:0005739	mitochondrion	PINX1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0000228	nuclear chromosome	PINX1	IDA		Human	PMID:19393617
Cellular Component	GO:0005730	nucleolus	PINX1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005730	nucleolus	PINX1	IDA		Human	PMID:11701125
Cellular Component	GO:0005730	nucleolus	PINX1	IDA		Human	PMID:19265708
Cellular Component	GO:0005730	nucleolus	PINX1	IDA		Human	PMID:19393617
Cellular Component	GO:0005730	nucleolus	PINX1	IDA		Human	PMID:21119197
Cellular Component	GO:0005730	nucleolus	PINX1	IDA		Human	PMID:24415760
Cellular Component	GO:0005730	nucleolus	pinx1	IDA		Zfish	PMID:18583067
Cellular Component	GO:0005654	nucleoplasm	PINX1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005819	spindle	PINX1	IDA		Human	PMID:19393617
Biological Process	GO:0007080	mitotic metaphase plate congression	PINX1	IMP		Human	PMID:19393617
Biological Process	GO:0010972	negative regulation of G2/M transition of mitotic cell cycle	PINX1	IDA		Human	PMID:11701125
Biological Process	GO:0031397	negative regulation of protein ubiquitination	PINX1	IMP		Human	PMID:24415760
Biological Process	GO:0051974	negative regulation of telomerase activity	PINX1	IDA		Human	PMID:11701125
Biological Process	GO:0051974	negative regulation of telomerase activity	PINX1	IMP		Human	PMID:11701125
Biological Process	GO:0051974	negative regulation of telomerase activity	PINX1	IMP		Human	PMID:21119197
Biological Process	GO:0032211	negative regulation of telomere maintenance via telomerase	PINX1	IDA		Human	PMID:11701125
Biological Process	GO:0032211	negative regulation of telomere maintenance via telomerase	PINX1	IMP		Human	PMID:21119197
Biological Process	GO:1904751	positive regulation of protein localization to nucleolus	PINX1	IDA		Human	PMID:19265708
Biological Process	GO:1904744	positive regulation of telomeric DNA binding	PINX1	IDA		Human	PMID:19265708
Biological Process	GO:1904744	positive regulation of telomeric DNA binding	PINX1	IDA		Human	PMID:24415760
Biological Process	GO:0070198	protein localization to chromosome, telomeric region	PINX1	IMP		Human	PMID:22749911
Biological Process	GO:1902570	protein localization to nucleolus	PINX1	IDA		Human	PMID:24415760
Biological Process	GO:0031647	regulation of protein stability	PINX1	IMP		Human	PMID:24415760
Biological Process	GO:0007004	telomere maintenance via telomerase	PINX1	IDA		Human	PMID:11701125

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern