Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PIP4K2C
  • Mouse genes Pip4k2c
  • Rat genes Pip4k2c
  • Zfish genes pip4k2ca,pip4k2cb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pip4k2c

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity	PIP4K2C	IDA		Human	PMID:26774281
Molecular Function	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity	Pip4k2c	IDA		Rat	PMID:9685379|RGD:633581
Molecular Function	GO:0042802	identical protein binding	PIP4K2C	IPI	UniProtKB:Q8TBX8	Human	PMID:18255255
Molecular Function	GO:0005515	protein binding	PIP4K2C	IPI	UniProtKB:Q99755	Human	PMID:31091439
Cellular Component	GO:0005776	autophagosome	PIP4K2C	IMP		Human	PMID:25578879
Cellular Component	GO:0005829	cytosol	PIP4K2C	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005783	endoplasmic reticulum	Pip4k2c	IDA		Rat	PMID:9685379|RGD:633581
Cellular Component	GO:0070062	extracellular exosome	PIP4K2C	HDA		Human	PMID:18570454
Cellular Component	GO:0070062	extracellular exosome	PIP4K2C	HDA		Human	PMID:19056867
Cellular Component	GO:0043229	intracellular organelle	PIP4K2C	IDA		Human	PMID:30718367
Cellular Component	GO:0005654	nucleoplasm	PIP4K2C	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	PIP4K2C	IDA		Human	GO_REF:0000052
Biological Process	GO:1902635	1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process	PIP4K2C	IDA		Human	PMID:26774281
Biological Process	GO:0090217	negative regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity	PIP4K2C	IMP		Human	PMID:31091439
Biological Process	GO:0046627	negative regulation of insulin receptor signaling pathway	PIP4K2C	IMP		Human	PMID:31091439
Biological Process	GO:2000786	positive regulation of autophagosome assembly	PIP4K2C	IMP		Human	PMID:25578879
Biological Process	GO:0010506	regulation of autophagy	PIP4K2C	IMP		Human	PMID:25578879

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern