Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PIP4P1
  • Mouse genes Pip4p1
  • Rat genes Pip4p1
  • Zfish genes pip4p1a,pip4p1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pip4p1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0034597	phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity	PIP4P1	IDA		Human	PMID:16365287
Molecular Function	GO:0005515	protein binding	PIP4P1	IPI	UniProtKB:P61421	Human	PMID:29644770
Molecular Function	GO:0005515	protein binding	PIP4P1	IPI	UniProtKB:Q6IAA8	Human	PMID:29644770
Molecular Function	GO:0005515	protein binding	PIP4P1	IPI	UniProtKB:O95208-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PIP4P1	IPI	UniProtKB:Q3KNW5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PIP4P1	IPI	UniProtKB:Q5EBL4-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PIP4P1	IPI	UniProtKB:Q96CS7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PIP4P1	IPI	UniProtKB:P61981	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PIP4P1	IPI	UniProtKB:Q15047-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PIP4P1	IPI	UniProtKB:Q8TAP4-4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PIP4P1	IPI	UniProtKB:Q92993	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Pip4p1	IPI	UniProtKB:P51863|UniProtKB:Q80X95|UniProtKB:Q99K70|UniProtKB:Q9CQ22	Mouse	MGI:MGI:6304515|PMID:29644770
Cellular Component	GO:0031902	late endosome membrane	PIP4P1	IDA		Human	PMID:16365287
Cellular Component	GO:0031902	late endosome membrane	Pip4p1	IDA		Mouse	MGI:MGI:6144310|PMID:29378918
Cellular Component	GO:0005765	lysosomal membrane	PIP4P1	IDA		Human	PMID:16365287
Cellular Component	GO:0005765	lysosomal membrane	PIP4P1	IDA		Human	PMID:29146937
Cellular Component	GO:0005765	lysosomal membrane	Pip4p1	IDA		Mouse	MGI:MGI:6304515|PMID:29644770
Cellular Component	GO:0030670	phagocytic vesicle membrane	Pip4p1	IDA		Mouse	MGI:MGI:6144310|PMID:29378918
Cellular Component	GO:0005886	plasma membrane	Pip4p1	IDA		Mouse	MGI:MGI:6144310|PMID:29378918
Biological Process	GO:0008203	cholesterol metabolic process	PIP4P1	IMP		Human	PMID:25035345
Biological Process	GO:0032418	lysosome localization	PIP4P1	IMP		Human	PMID:29146937
Biological Process	GO:0046856	phosphatidylinositol dephosphorylation	PIP4P1	IDA		Human	PMID:16365287
Biological Process	GO:1904263	positive regulation of TORC1 signaling	PIP4P1	IMP		Human	PMID:29644770
Biological Process	GO:1904263	positive regulation of TORC1 signaling	Pip4p1	IMP		Mouse	MGI:MGI:6304515|PMID:29644770
Biological Process	GO:0070070	proton-transporting V-type ATPase complex assembly	Pip4p1	IMP		Mouse	MGI:MGI:6304515|PMID:29644770
Biological Process	GO:0006991	response to sterol depletion	PIP4P1	IDA		Human	PMID:25035345
Biological Process	GO:0006991	response to sterol depletion	PIP4P1	IDA		Human	PMID:29146937

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern