Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PIP5K1C
  • Mouse genes Pip5k1c
  • Rat genes Pip5k1c
  • Zfish genes pip5k1ca,pip5k1cb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pip5k1c

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity	Pip5k1c	IDA		Mouse	MGI:MGI:6478055|PMID:22942276
Molecular Function	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity	Pip5k1c	IDA		Mouse	PMID:9535851
Molecular Function	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity	Pip5k1c	IDA		Mouse	PMID:14741049
Molecular Function	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity	Pip5k1c	IMP	MGI:MGI:3054978	Mouse	PMID:20622009
Molecular Function	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity	Pip5k1c	IDA		Mouse	PMID:20622009
Molecular Function	GO:0005515	protein binding	PIP5K1C	IPI	UniProtKB:Q86VI4	Human	PMID:25588945
Molecular Function	GO:0005515	protein binding	PIP5K1C	IPI	UniProtKB:Q9Y490	Human	PMID:35044719
Molecular Function	GO:0005515	protein binding	Pip5k1c	IPI	UniProtKB:Q9DBG3-1|UniProtKB:Q9DBG3-2	Mouse	MGI:MGI:3703857|PMID:17290217
Cellular Component	GO:0005829	cytosol	PIP5K1C	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	Pip5k1c	IDA		Mouse	PMID:20622009
Cellular Component	GO:0010008	endosome membrane	PIP5K1C	IDA		Human	PMID:25588945
Cellular Component	GO:0098978	glutamatergic synapse	Pip5k1c	IEP		Mouse	PMID:22243752
Cellular Component	GO:0098978	glutamatergic synapse	Pip5k1c	IDA		Mouse	PMID:22243752
Cellular Component	GO:0098978	glutamatergic synapse	Pip5k1c	IMP		Mouse	PMID:22243752
Cellular Component	GO:0005654	nucleoplasm	PIP5K1C	IDA		Human	GO_REF:0000052
Cellular Component	GO:0014069	postsynaptic density	Pip5k1c	IDA		Mouse	PMID:22243752
Cellular Component	GO:0014069	postsynaptic density	Pip5k1c	IMP		Mouse	PMID:22243752
Cellular Component	GO:0014069	postsynaptic density	Pip5k1c	IEP		Mouse	PMID:22243752
Cellular Component	GO:0098835	presynaptic endocytic zone membrane	Pip5k1c	IDA		Rat	PMID:11604140|RGD:13702138
Biological Process	GO:0007409	axonogenesis	Pip5k1c	IDA		Mouse	PMID:14741049
Biological Process	GO:0006661	phosphatidylinositol biosynthetic process	Pip5k1c	IDA		Mouse	PMID:20622009
Biological Process	GO:0006661	phosphatidylinositol biosynthetic process	Pip5k1c	IMP	MGI:MGI:3054978	Mouse	PMID:20622009
Biological Process	GO:0046488	phosphatidylinositol metabolic process	Pip5k1c	IDA		Mouse	PMID:14741049
Biological Process	GO:0046488	phosphatidylinositol metabolic process	Pip5k1c	IDA		Mouse	PMID:9535851
Biological Process	GO:0070527	platelet aggregation	Pip5k1c	IMP	MGI:MGI:2385922,MGI:MGI:5496877	Mouse	PMID:23372168
Biological Process	GO:0099149	regulation of postsynaptic neurotransmitter receptor internalization	Pip5k1c	IEP		Mouse	PMID:22243752
Biological Process	GO:0099149	regulation of postsynaptic neurotransmitter receptor internalization	Pip5k1c	IDA		Mouse	PMID:22243752
Biological Process	GO:0099149	regulation of postsynaptic neurotransmitter receptor internalization	Pip5k1c	IMP		Mouse	PMID:22243752
Biological Process	GO:1900242	regulation of synaptic vesicle endocytosis	Pip5k1c	IMP		Mouse	PMID:15386003
Biological Process	GO:1900242	regulation of synaptic vesicle endocytosis	Pip5k1c	IDA		Mouse	PMID:15386003

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern