Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PIP5KL1
  • Mouse genes Pip5kl1
  • Rat genes Pip5kl1
  • Zfish genes pip5kl1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pip5kl1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity	Pip5kl1	IDA		Mouse	PMID:14701839
Molecular Function	GO:0005515	protein binding	Pip5kl1	IPI	PR:P70181	Mouse	PMID:14701839
Molecular Function	GO:0005515	protein binding	Pip5kl1	IPI	PR:P70182	Mouse	PMID:14701839
Cellular Component	GO:0042995	cell projection	Pip5kl1	IDA		Mouse	PMID:14701839
Cellular Component	GO:0005829	cytosol	PIP5KL1	IDA		Human	GO_REF:0000052
Biological Process	GO:0030336	negative regulation of cell migration	PIP5KL1	IMP		Human	PMID:19680787
Biological Process	GO:0010917	negative regulation of mitochondrial membrane potential	PIP5KL1	IDA		Human	PMID:16751333
Biological Process	GO:0001933	negative regulation of protein phosphorylation	PIP5KL1	IMP		Human	PMID:19680787
Biological Process	GO:0043065	positive regulation of apoptotic process	PIP5KL1	IDA		Human	PMID:16751333

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern