About   Help   FAQ
Comparative GO Graph (mouse, human, rat)
Source
Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Pira13

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pira13
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0015026coreceptor activityLILRA4IDAHumanPMID:16735691
Molecular FunctionGO:0001791IgM bindingLILRA2IDAHumanPMID:27572839
Molecular FunctionGO:0005515protein bindingLILRB3IPIUniProtKB:P29350HumanPMID:18802077
Molecular FunctionGO:0005515protein bindingLILRB3IPIUniProtKB:P05783HumanPMID:26769854
Molecular FunctionGO:0005515protein bindingLILRB3IPIUniProtKB:P05787HumanPMID:26769854
Molecular FunctionGO:0005515protein bindingLILRA4IPIUniProtKB:Q10589HumanPMID:19564354
Molecular FunctionGO:0005102signaling receptor bindingLILRA4IPIUniProtKB:P30273HumanPMID:16735691
Cellular ComponentGO:0032998Fc-epsilon receptor I complexLILRA4IDAHumanPMID:16735691
Cellular ComponentGO:0005886plasma membraneLILRA4IDAHumanPMID:16735691
Cellular ComponentGO:0005886plasma membraneLILRA2IDAHumanPMID:22479404
Cellular ComponentGO:0005886plasma membraneLILRA2IDAHumanPMID:27572839
Biological ProcessGO:0038095Fc-epsilon receptor signaling pathwayLILRA4IMPHumanPMID:16735691
Biological ProcessGO:0002220innate immune response activating cell surface receptor signaling pathwayLILRA2IDAHumanPMID:27572839
Biological ProcessGO:0032687negative regulation of interferon-alpha productionLILRA4IMPHumanPMID:16735691
Biological ProcessGO:0031665negative regulation of lipopolysaccharide-mediated signaling pathwayLILRA2IMPHumanPMID:22479404
Biological ProcessGO:0045671negative regulation of osteoclast differentiationLILRB3IDAHumanPMID:18802077
Biological ProcessGO:0034144negative regulation of toll-like receptor 4 signaling pathwayLILRA2IMPHumanPMID:22479404
Biological ProcessGO:0034156negative regulation of toll-like receptor 7 signaling pathwayLILRA4IMPHumanPMID:16735691
Biological ProcessGO:0034164negative regulation of toll-like receptor 9 signaling pathwayLILRA4IMPHumanPMID:16735691
Biological ProcessGO:0032720negative regulation of tumor necrosis factor productionLILRA4IMPHumanPMID:16735691
Biological ProcessGO:0002283neutrophil activation involved in immune responseLILRA2IDAHumanPMID:27572839
Biological ProcessGO:0051928positive regulation of calcium ion transportLILRA2IDAHumanPMID:12393390
Biological ProcessGO:0050867positive regulation of cell activationLILRA2IDAHumanPMID:12393390
Biological ProcessGO:0071657positive regulation of granulocyte colony-stimulating factor productionLILRA2IMPHumanPMID:22479404
Biological ProcessGO:0032725positive regulation of granulocyte macrophage colony-stimulating factor productionLILRA2IMPHumanPMID:22479404
Biological ProcessGO:0032731positive regulation of interleukin-1 beta productionLILRA2IDAHumanPMID:12393390
Biological ProcessGO:0032755positive regulation of interleukin-6 productionLILRA2IDAHumanPMID:12393390
Biological ProcessGO:0032755positive regulation of interleukin-6 productionLILRA2IMPHumanPMID:22479404
Biological ProcessGO:0032757positive regulation of interleukin-8 productionLILRA2IMPHumanPMID:22479404
Biological ProcessGO:0032760positive regulation of tumor necrosis factor productionLILRA2IDAHumanPMID:12393390

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IEP Inferred from expression pattern
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction
  HTP Inferred from High Throughput Experiment
  HDA Inferred from High Throughput Direct Assay
  HMP Inferred from High Throughput Mutant Phenotype
  HGI Inferred from High Throughput Genetic Interaction
  HEP Inferred from High Throughput Expression Pattern

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
12/10/2024
MGI 6.24
The Jackson Laboratory