Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PKD2
  • Mouse genes Pkd2
  • Rat genes Pkd2
  • Zfish genes pkd2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pkd2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042805	actinin binding	PKD2	IDA		Human	PMID:15843396
Molecular Function	GO:0051393	alpha-actinin binding	Pkd2	IPI	RGD:70907	Rat	PMID:15843396|RGD:7175289
Molecular Function	GO:0051117	ATPase binding	Pkd2	IPI	PR:Q01853	Mouse	PMID:18178578
Molecular Function	GO:0005262	calcium channel activity	PKD2	IDA		Human	PMID:27214281
Molecular Function	GO:0005262	calcium channel activity	Pkd2	IMP		Mouse	MGI:MGI:5883145|PMID:27760766
Molecular Function	GO:0005262	calcium channel activity	Pkd2	IDA		Mouse	PMID:12640140
Molecular Function	GO:0005509	calcium ion binding	PKD2	IDA		Human	PMID:24990821
Molecular Function	GO:0005509	calcium ion binding	Pkd2	IDA		Mouse	MGI:MGI:5315681|PMID:20408813
Molecular Function	GO:0048763	calcium-induced calcium release activity	PKD2	IDA		Human	PMID:11854751
Molecular Function	GO:0015267	channel activity	Pkd2	IMP	MGI:MGI:1860840	Mouse	PMID:18235088
Molecular Function	GO:0008092	cytoskeletal protein binding	PKD2	IDA		Human	PMID:10760273
Molecular Function	GO:0043398	HLH domain binding	PKD2	IPI	UniProtKB:Q02363	Human	PMID:16311606
Molecular Function	GO:0042802	identical protein binding	PKD2	IPI	UniProtKB:Q13563	Human	PMID:20168298
Molecular Function	GO:0042802	identical protein binding	PKD2	IPI	UniProtKB:Q13563	Human	PMID:27768895
Molecular Function	GO:0042802	identical protein binding	PKD2	IPI	UniProtKB:Q13563	Human	PMID:28092368
Molecular Function	GO:0042802	identical protein binding	Pkd2	IPI	UniProtKB:O35245	Mouse	MGI:MGI:5315681|PMID:20408813
Molecular Function	GO:0005261	monoatomic cation channel activity	PKD2	IMP		Human	PMID:29899465
Molecular Function	GO:0051371	muscle alpha-actinin binding	Pkd2	IPI	RGD:1308097	Rat	PMID:15843396|RGD:7175289
Molecular Function	GO:0015271	outward rectifier potassium channel activity	Pkd2	IMP		Mouse	MGI:MGI:5883145|PMID:27760766
Molecular Function	GO:0051219	phosphoprotein binding	PKD2	IPI	UniProtKB:P14314	Human	PMID:19801576
Molecular Function	GO:0005267	potassium channel activity	PKD2	IDA		Human	PMID:26269590
Molecular Function	GO:0005267	potassium channel activity	Pkd2	IDA		Mouse	PMID:12640140
Molecular Function	GO:0005515	protein binding	PKD2	IPI	UniProtKB:P48995	Human	PMID:10097141
Molecular Function	GO:0005515	protein binding	PKD2	IPI	UniProtKB:P48995-2	Human	PMID:10097141
Molecular Function	GO:0005515	protein binding	PKD2	IPI	UniProtKB:P98161	Human	PMID:10097141
Molecular Function	GO:0005515	protein binding	PKD2	IPI	UniProtKB:O35387	Human	PMID:10760273
Molecular Function	GO:0005515	protein binding	PKD2	IPI	UniProtKB:P19429	Human	PMID:12525172
Molecular Function	GO:0005515	protein binding	PKD2	IPI	UniProtKB:P19429	Human	PMID:12809519
Molecular Function	GO:0005515	protein binding	PKD2	IPI	UniProtKB:O08808	Human	PMID:15123714
Molecular Function	GO:0005515	protein binding	PKD2	IPI	UniProtKB:O60610	Human	PMID:15123714
Molecular Function	GO:0005515	protein binding	PKD2	IPI	UniProtKB:Q9Y3M2	Human	PMID:15194699
Molecular Function	GO:0005515	protein binding	PKD2	IPI	UniProtKB:Q6VY07	Human	PMID:15692563
Molecular Function	GO:0005515	protein binding	PKD2	IPI	UniProtKB:Q91908	Human	PMID:16223735
Molecular Function	GO:0005515	protein binding	PKD2	IPI	UniProtKB:Q02363	Human	PMID:16311606
Molecular Function	GO:0005515	protein binding	PKD2	IPI	UniProtKB:P08F94	Human	PMID:18235088
Molecular Function	GO:0005515	protein binding	PKD2	IPI	UniProtKB:Q9QZC1	Human	PMID:19812035
Molecular Function	GO:0005515	protein binding	PKD2	IPI	UniProtKB:P98161	Human	PMID:20168298
Molecular Function	GO:0005515	protein binding	PKD2	IPI	UniProtKB:P48995	Human	PMID:25114176
Molecular Function	GO:0005515	protein binding	PKD2	IPI	UniProtKB:Q9EPK8	Human	PMID:25114176
Molecular Function	GO:0005515	protein binding	PKD2	IPI	UniProtKB:O15162	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PKD2	IPI	UniProtKB:P43361	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PKD2	IPI	UniProtKB:P60410	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PKD2	IPI	UniProtKB:Q6A162	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PKD2	IPI	UniProtKB:P43361	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	PKD2	IPI	UniProtKB:P98161-1	Human	PMID:30093605
Molecular Function	GO:0005515	protein binding	PKD2	IPI	UniProtKB:A8MQ03	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKD2	IPI	UniProtKB:O75031	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKD2	IPI	UniProtKB:Q3LI66	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKD2	IPI	UniProtKB:Q99750	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKD2	IPI	UniProtKB:P98161	Human	PMID:9171830
Molecular Function	GO:0005515	protein binding	PKD2	IPI	UniProtKB:P98161	Human	PMID:9192675
Molecular Function	GO:0005515	protein binding	Pkd2	IPI	UniProtKB:O08852	Mouse	MGI:MGI:6210198|PMID:25405894
Molecular Function	GO:0005515	protein binding	Pkd2	IPI	UniProtKB:P84309	Mouse	MGI:MGI:5014446|PMID:21670265
Molecular Function	GO:0005515	protein binding	Pkd2	IPI	UniProtKB:Q8R526	Mouse	MGI:MGI:4946570|PMID:21307093
Molecular Function	GO:0005515	protein binding	Pkd2	IPI	UniProtKB:Q91ZR4	Mouse	MGI:MGI:3849381|PMID:18235101
Molecular Function	GO:0005515	protein binding	Pkd2	IPI	UniProtKB:E2JF22	Mouse	MGI:MGI:5613452|PMID:24157948
Molecular Function	GO:0005515	protein binding	Pkd2	IPI	PR:Q9JLQ0	Mouse	PMID:10913159
Molecular Function	GO:0005515	protein binding	Pkd2	IPI	PR:O08852	Mouse	PMID:12007403
Molecular Function	GO:0005515	protein binding	Pkd2	IPI	PR:O08852	Mouse	PMID:11901144
Molecular Function	GO:0005515	protein binding	Pkd2	IPI	MGI:MGI:2155808	Mouse	PMID:18235088
Molecular Function	GO:0005515	protein binding	Pkd2	IPI	PR:Q8K3K8	Mouse	PMID:15607428
Molecular Function	GO:0042803	protein homodimerization activity	PKD2	IDA		Human	PMID:9192675
Molecular Function	GO:0005102	signaling receptor binding	PKD2	IPI	UniProtKB:Q91908	Human	PMID:16223735
Molecular Function	GO:0005102	signaling receptor binding	Pkd2	IPI	PR:E9Q401	Mouse	PMID:17404231
Molecular Function	GO:0044325	transmembrane transporter binding	PKD2	IPI	UniProtKB:P48995-1	Human	PMID:10097141
Molecular Function	GO:0005245	voltage-gated calcium channel activity	PKD2	IDA		Human	PMID:11252306
Molecular Function	GO:0005245	voltage-gated calcium channel activity	PKD2	IDA		Human	PMID:15692563
Molecular Function	GO:0022843	voltage-gated monoatomic cation channel activity	PKD2	IDA		Human	PMID:11252306
Molecular Function	GO:0005244	voltage-gated monoatomic ion channel activity	PKD2	IDA		Human	PMID:11854751
Molecular Function	GO:0005249	voltage-gated potassium channel activity	PKD2	IMP		Human	PMID:27071085
Molecular Function	GO:0005248	voltage-gated sodium channel activity	PKD2	IDA		Human	PMID:11252306
Molecular Function	GO:0005248	voltage-gated sodium channel activity	PKD2	IMP		Human	PMID:27071085
Cellular Component	GO:0045180	basal cortex	PKD2	IDA		Human	PMID:10770959
Cellular Component	GO:0045180	basal cortex	Pkd2	IDA		Mouse	MGI:MGI:4942265|PMID:10770959
Cellular Component	GO:0009925	basal plasma membrane	PKD2	IDA		Human	PMID:10770959
Cellular Component	GO:0016323	basolateral plasma membrane	pkd2	IDA		Zfish	PMID:18701462
Cellular Component	GO:0016323	basolateral plasma membrane	pkd2	IDA		Zfish	PMID:18417723
Cellular Component	GO:0034703	cation channel complex	PKD2	IDA		Human	PMID:30093605
Cellular Component	GO:0005911	cell-cell junction	Pkd2	IDA		Mouse	MGI:MGI:5315353|PMID:15843396
Cellular Component	GO:0036064	ciliary basal body	PKD2	IDA		Human	PMID:15337773
Cellular Component	GO:0036064	ciliary basal body	Pkd2	IDA		Mouse	PMID:22031837
Cellular Component	GO:0060170	ciliary membrane	Pkd2	IMP		Mouse	MGI:MGI:5883145|PMID:27760766
Cellular Component	GO:0005929	cilium	PKD2	IDA		Human	PMID:28154160
Cellular Component	GO:0005929	cilium	Pkd2	IMP		Mouse	MGI:MGI:4946570|PMID:21307093
Cellular Component	GO:0005929	cilium	Pkd2	IDA		Mouse	MGI:MGI:6210198|PMID:25405894
Cellular Component	GO:0005929	cilium	Pkd2	IDA		Mouse	MGI:MGI:5315687|PMID:19265036
Cellular Component	GO:0005929	cilium	Pkd2	IDA		Mouse	PMID:21685914
Cellular Component	GO:0005929	cilium	Pkd2	IDA		Mouse	PMID:28154160
Cellular Component	GO:0005929	cilium	Pkd2	IDA		Mouse	PMID:16316413
Cellular Component	GO:0005929	cilium	Pkd2	IDA		Mouse	PMID:12640140
Cellular Component	GO:0005929	cilium	Pkd2	IDA		Mouse	PMID:12514735
Cellular Component	GO:0005929	cilium	Pkd2	IDA		Mouse	PMID:18552856
Cellular Component	GO:0005929	cilium	pkd2	IDA		Zfish	PMID:18701462
Cellular Component	GO:0005929	cilium	pkd2	IDA		Zfish	PMID:18417723
Cellular Component	GO:0005737	cytoplasm	PKD2	IDA		Human	PMID:10770959
Cellular Component	GO:0005737	cytoplasm	PKD2	IMP		Human	PMID:16311606
Cellular Component	GO:0005737	cytoplasm	Pkd2	IDA		Mouse	MGI:MGI:4942265|PMID:10770959
Cellular Component	GO:0098554	cytoplasmic side of endoplasmic reticulum membrane	PKD2	IDA		Human	PMID:21044049
Cellular Component	GO:0005829	cytosol	PKD2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005783	endoplasmic reticulum	PKD2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005783	endoplasmic reticulum	PKD2	IDA		Human	PMID:10760273
Cellular Component	GO:0005783	endoplasmic reticulum	PKD2	IDA		Human	PMID:15123714
Cellular Component	GO:0005783	endoplasmic reticulum	PKD2	IDA		Human	PMID:15692563
Cellular Component	GO:0005783	endoplasmic reticulum	PKD2	IMP		Human	PMID:16223735
Cellular Component	GO:0005783	endoplasmic reticulum	PKD2	IDA		Human	PMID:19801576
Cellular Component	GO:0005783	endoplasmic reticulum	PKD2	IDA		Human	PMID:28154160
Cellular Component	GO:0005783	endoplasmic reticulum	Pkd2	IDA		Mouse	MGI:MGI:6210198|PMID:25405894
Cellular Component	GO:0005783	endoplasmic reticulum	Pkd2	IMP		Mouse	PMID:12640140
Cellular Component	GO:0005783	endoplasmic reticulum	Pkd2	IDA		Mouse	PMID:16192288
Cellular Component	GO:0005783	endoplasmic reticulum	Pkd2	IDA		Rat	PMID:12089381|RGD:7175293
Cellular Component	GO:0005783	endoplasmic reticulum	pkd2	IDA		Zfish	PMID:18417723
Cellular Component	GO:0005789	endoplasmic reticulum membrane	PKD2	IDA		Human	PMID:11854751
Cellular Component	GO:0005789	endoplasmic reticulum membrane	PKD2	IDA		Human	PMID:15001556
Cellular Component	GO:0070062	extracellular exosome	PKD2	HDA		Human	PMID:19056867
Cellular Component	GO:0005794	Golgi apparatus	Pkd2	IDA		Mouse	MGI:MGI:6210198|PMID:25405894
Cellular Component	GO:0030027	lamellipodium	PKD2	IDA		Human	PMID:10760273
Cellular Component	GO:0098553	lumenal side of endoplasmic reticulum membrane	PKD2	IDA		Human	PMID:21044049
Cellular Component	GO:0016020	membrane	Pkd2	IDA		Rat	PMID:12454224|RGD:1580868
Cellular Component	GO:0072686	mitotic spindle	PKD2	IDA		Human	PMID:15123714
Cellular Component	GO:0072686	mitotic spindle	Pkd2	IDA		Mouse	MGI:MGI:5315358|PMID:15123714
Cellular Component	GO:0031514	motile cilium	Pkd2	IDA		Mouse	PMID:15858826
Cellular Component	GO:0097730	non-motile cilium	Pkd2	IDA		Mouse	PMID:12062067
Cellular Component	GO:0005886	plasma membrane	PKD2	IDA		Human	PMID:15692563
Cellular Component	GO:0005886	plasma membrane	PKD2	IDA		Human	PMID:16025301
Cellular Component	GO:0005886	plasma membrane	PKD2	IDA		Human	PMID:21044049
Cellular Component	GO:0005886	plasma membrane	PKD2	IDA		Human	PMID:26269590
Cellular Component	GO:0005886	plasma membrane	PKD2	IMP		Human	PMID:27071085
Cellular Component	GO:0005886	plasma membrane	PKD2	IDA		Human	PMID:28092368
Cellular Component	GO:0005886	plasma membrane	PKD2	IDA		Human	PMID:29899465
Cellular Component	GO:0005886	plasma membrane	PKD2	IDA		Human	PMID:30093605
Cellular Component	GO:0005886	plasma membrane	Pkd2	IDA		Mouse	PMID:12640140
Cellular Component	GO:0002133	polycystin complex	PKD2	IPI		Human	PMID:11901144
Cellular Component	GO:0002133	polycystin complex	Pkd2	IPI		Mouse	MGI:MGI:2180983|PMID:11901144
Cellular Component	GO:0002133	polycystin complex	Pkd2	IDA		Mouse	MGI:MGI:6210198|PMID:25405894
Cellular Component	GO:0002133	polycystin complex	Pkd2	IDA		Mouse	PMID:11901144
Biological Process	GO:0035904	aorta development	PKD2	IEP		Human	PMID:11891195
Biological Process	GO:0003171	atrioventricular valve development	pkd2	IMP	ZFIN:ZDB-GENO-980202-1193	Zfish	PMID:25959969
Biological Process	GO:0001658	branching involved in ureteric bud morphogenesis	PKD2	IEP		Human	PMID:11891195
Biological Process	GO:0070588	calcium ion transmembrane transport	PKD2	IDA		Human	PMID:11854751
Biological Process	GO:0070588	calcium ion transmembrane transport	Pkd2	IMP		Mouse	MGI:MGI:5883145|PMID:27760766
Biological Process	GO:0006816	calcium ion transport	PKD2	IDA		Human	PMID:11252306
Biological Process	GO:0006816	calcium ion transport	PKD2	IDA		Human	PMID:27214281
Biological Process	GO:0006816	calcium ion transport	Pkd2	IDA		Mouse	MGI:MGI:2449360|PMID:12514735
Biological Process	GO:0006816	calcium ion transport	Pkd2	IMP		Mouse	PMID:12514735
Biological Process	GO:0198738	cell-cell signaling by wnt	PKD2	IDA		Human	PMID:27214281
Biological Process	GO:0071277	cellular response to calcium ion	Pkd2	IMP		Mouse	MGI:MGI:5883145|PMID:27760766
Biological Process	GO:0071320	cellular response to cAMP	PKD2	IMP		Human	PMID:26269590
Biological Process	GO:0071498	cellular response to fluid shear stress	PKD2	IMP		Human	PMID:19265036
Biological Process	GO:0071498	cellular response to fluid shear stress	Pkd2	IMP		Mouse	MGI:MGI:5315687|PMID:19265036
Biological Process	GO:0071464	cellular response to hydrostatic pressure	PKD2	IDA		Human	PMID:16025301
Biological Process	GO:0097704	cellular response to oscillatory fluid shear stress	pkd2	IMP	ZFIN:ZDB-GENO-980202-1193	Zfish	PMID:25959969
Biological Process	GO:0071470	cellular response to osmotic stress	PKD2	IDA		Human	PMID:16025301
Biological Process	GO:0060271	cilium assembly	pkd2	IMP	ZFIN:ZDB-MRPHLNO-060630-4	Zfish	PMID:31015398
Biological Process	GO:0044782	cilium organization	PKD2	IMP		Human	PMID:28154160
Biological Process	GO:0042994	cytoplasmic sequestering of transcription factor	PKD2	IMP		Human	PMID:16311606
Biological Process	GO:0050982	detection of mechanical stimulus	Pkd2	IMP		Mouse	PMID:12514735
Biological Process	GO:0003127	detection of nodal flow	Pkd2	IMP		Mouse	MGI:MGI:4946570|PMID:21307093
Biological Process	GO:0061371	determination of heart left/right asymmetry	pkd2	IMP	ZFIN:ZDB-GENO-040830-2	Zfish	PMID:25660539
Biological Process	GO:0061371	determination of heart left/right asymmetry	pkd2	IMP	ZFIN:ZDB-MRPHLNO-060630-4	Zfish	PMID:25660539
Biological Process	GO:0007368	determination of left/right symmetry	Pkd2	IMP	MGI:MGI:2676373	Mouse	PMID:12062060
Biological Process	GO:0007368	determination of left/right symmetry	pkd2	IMP	ZFIN:ZDB-MRPHLNO-070620-5	Zfish	PMID:17360770
Biological Process	GO:0007368	determination of left/right symmetry	pkd2	IMP	ZFIN:ZDB-GENO-040830-2	Zfish	PMID:25660539
Biological Process	GO:0007368	determination of left/right symmetry	pkd2	IMP		Zfish	PMID:9334285
Biological Process	GO:0007368	determination of left/right symmetry	pkd2	IMP	ZFIN:ZDB-MRPHLNO-070129-2	Zfish	PMID:16943304
Biological Process	GO:0007368	determination of left/right symmetry	pkd2	IMP	ZFIN:ZDB-MRPHLNO-070129-3	Zfish	PMID:18417723
Biological Process	GO:0007368	determination of left/right symmetry	pkd2	IMP	ZFIN:ZDB-GENO-980202-870	Zfish	PMID:17360770
Biological Process	GO:0007368	determination of left/right symmetry	pkd2	IMP	ZFIN:ZDB-MRPHLNO-070620-6	Zfish	PMID:17360770
Biological Process	GO:0007368	determination of left/right symmetry	pkd2	IGI	ZFIN:ZDB-MRPHLNO-060630-4,ZFIN:ZDB-MRPHLNO-110527-1	Zfish	PMID:21490950
Biological Process	GO:0007368	determination of left/right symmetry	pkd2	IMP	ZFIN:ZDB-MRPHLNO-060630-4	Zfish	PMID:25660539
Biological Process	GO:0007368	determination of left/right symmetry	pkd2	IMP	ZFIN:ZDB-GENO-980202-1193	Zfish	PMID:17360770
Biological Process	GO:0007368	determination of left/right symmetry	pkd2	IMP	ZFIN:ZDB-MRPHLNO-060630-4	Zfish	PMID:20168298
Biological Process	GO:0071910	determination of liver left/right asymmetry	PKD2	IMP		Human	PMID:21719175
Biological Process	GO:0009953	dorsal/ventral pattern formation	pkd2	IMP	ZFIN:ZDB-MRPHLNO-060630-4	Zfish	PMID:19488022
Biological Process	GO:0003143	embryonic heart tube morphogenesis	pkd2	IMP		Zfish	PMID:9334285
Biological Process	GO:0001892	embryonic placenta development	Pkd2	IMP		Mouse	MGI:MGI:4836293|PMID:20862291
Biological Process	GO:0001892	embryonic placenta development	Pkd2	IMP	MGI:MGI:1860840	Mouse	PMID:16301212
Biological Process	GO:0051649	establishment of localization in cell	Pkd2	IMP		Mouse	PMID:12514735
Biological Process	GO:0051649	establishment of localization in cell	Pkd2	IMP	MGI:MGI:1860866	Mouse	PMID:17404231
Biological Process	GO:0007507	heart development	PKD2	IEP		Human	PMID:11891195
Biological Process	GO:0007507	heart development	Pkd2	IMP	MGI:MGI:1860866	Mouse	PMID:10615132
Biological Process	GO:0007507	heart development	pkd2	IMP		Zfish	PMID:23376035|ZFIN:ZDB-PUB-130218-3
Biological Process	GO:0003146	heart jogging	pkd2	IMP		Zfish	PMID:9334285
Biological Process	GO:0001947	heart looping	PKD2	IMP		Human	PMID:21719175
Biological Process	GO:0001947	heart looping	pkd2	IMP	ZFIN:ZDB-MRPHLNO-070129-3	Zfish	PMID:18417723
Biological Process	GO:0001947	heart looping	pkd2	IMP		Zfish	PMID:9334285
Biological Process	GO:0098662	inorganic cation transmembrane transport	PKD2	IMP		Human	PMID:29899465
Biological Process	GO:0006874	intracellular calcium ion homeostasis	Pkd2	IMP	MGI:MGI:1860866	Mouse	PMID:12874107
Biological Process	GO:0001822	kidney development	Pkd2	IGI	MGI:MGI:97603	Mouse	PMID:21685914
Biological Process	GO:0001822	kidney development	Pkd2	IMP	MGI:MGI:1860866	Mouse	PMID:10615132
Biological Process	GO:0001822	kidney development	pkd2	IMP	ZFIN:ZDB-MRPHLNO-060630-4	Zfish	PMID:24235270
Biological Process	GO:0070121	Kupffer's vesicle development	pkd2	IGI	ZFIN:ZDB-MRPHLNO-060630-4,ZFIN:ZDB-MRPHLNO-070620-5,ZFIN:ZDB-MRPHLNO-160201-1	Zfish	PMID:26432887
Biological Process	GO:0070121	Kupffer's vesicle development	pkd2	IMP	ZFIN:ZDB-MRPHLNO-060630-4,ZFIN:ZDB-MRPHLNO-070620-5	Zfish	PMID:26432887
Biological Process	GO:0060972	left/right pattern formation	pkd2	IMP	ZFIN:ZDB-MRPHLNO-070129-3	Zfish	PMID:30080851
Biological Process	GO:0001889	liver development	PKD2	IEP		Human	PMID:11891195
Biological Process	GO:0001889	liver development	Pkd2	IGI	MGI:MGI:97603	Mouse	PMID:21685914
Biological Process	GO:0001946	lymphangiogenesis	pkd2	IMP	ZFIN:ZDB-MRPHLNO-070129-1	Zfish	PMID:24767999
Biological Process	GO:0072177	mesonephric duct development	PKD2	IEP		Human	PMID:11891195
Biological Process	GO:0072164	mesonephric tubule development	PKD2	IEP		Human	PMID:11891195
Biological Process	GO:0072218	metanephric ascending thin limb development	PKD2	IEP		Human	PMID:11891195
Biological Process	GO:0072214	metanephric cortex development	PKD2	IEP		Human	PMID:11891195
Biological Process	GO:0072219	metanephric cortical collecting duct development	PKD2	IEP		Human	PMID:11891195
Biological Process	GO:0072235	metanephric distal tubule development	PKD2	IEP		Human	PMID:11891195
Biological Process	GO:0072075	metanephric mesenchyme development	PKD2	IEP		Human	PMID:11891195
Biological Process	GO:0035502	metanephric part of ureteric bud development	PKD2	IEP		Human	PMID:11891195
Biological Process	GO:0072284	metanephric S-shaped body morphogenesis	PKD2	IEP		Human	PMID:11891195
Biological Process	GO:0072208	metanephric smooth muscle tissue development	PKD2	IEP		Human	PMID:11891195
Biological Process	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle	PKD2	IMP		Human	PMID:16311606
Biological Process	GO:0060315	negative regulation of ryanodine-sensitive calcium-release channel activity	Pkd2	IDA		Mouse	PMID:17404231
Biological Process	GO:0021915	neural tube development	PKD2	IEP		Human	PMID:11891195
Biological Process	GO:0007219	Notch signaling pathway	pkd2	IMP	ZFIN:ZDB-MRPHLNO-060630-4	Zfish	PMID:31015398
Biological Process	GO:0060674	placenta blood vessel development	Pkd2	IMP		Mouse	MGI:MGI:4836293|PMID:20862291
Biological Process	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity	PKD2	IMP		Human	PMID:16311606
Biological Process	GO:0007204	positive regulation of cytosolic calcium ion concentration	Pkd2	IMP		Rat	PMID:16952559|RGD:7175288
Biological Process	GO:0010628	positive regulation of gene expression	Pkd2	IMP		Mouse	MGI:MGI:4440396|PMID:20181743
Biological Process	GO:0031587	positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity	PKD2	IMP		Human	PMID:16223735
Biological Process	GO:0045429	positive regulation of nitric oxide biosynthetic process	PKD2	IMP		Human	PMID:19265036
Biological Process	GO:0045429	positive regulation of nitric oxide biosynthetic process	Pkd2	IMP		Mouse	MGI:MGI:5315687|PMID:19265036
Biological Process	GO:0051284	positive regulation of sequestering of calcium ion	pkd2	IMP		Zfish	PMID:23376035|ZFIN:ZDB-PUB-130218-3
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	PKD2	IDA		Human	PMID:16311606
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	PKD2	IMP		Human	PMID:9192675
Biological Process	GO:0071805	potassium ion transmembrane transport	PKD2	IDA		Human	PMID:26269590
Biological Process	GO:0071805	potassium ion transmembrane transport	PKD2	IMP		Human	PMID:27071085
Biological Process	GO:0071805	potassium ion transmembrane transport	Pkd2	IMP		Mouse	MGI:MGI:5883145|PMID:27760766
Biological Process	GO:0048793	pronephros development	pkd2	IGI	ZFIN:ZDB-MRPHLNO-060630-4,ZFIN:ZDB-MRPHLNO-101122-2	Zfish	PMID:20729296
Biological Process	GO:0048793	pronephros development	pkd2	IMP	ZFIN:ZDB-MRPHLNO-070129-3	Zfish	PMID:18417723
Biological Process	GO:0048793	pronephros development	pkd2	IGI	ZFIN:ZDB-MRPHLNO-070129-2,ZFIN:ZDB-MRPHLNO-100224-1	Zfish	PMID:19801576
Biological Process	GO:0048793	pronephros development	pkd2	IGI	ZFIN:ZDB-GENE-040426-770	Zfish	PMID:19801576
Biological Process	GO:0048793	pronephros development	pkd2	IGI	ZFIN:ZDB-MRPHLNO-060630-4,ZFIN:ZDB-MRPHLNO-150814-3	Zfish	PMID:24700876
Biological Process	GO:0048793	pronephros development	pkd2	IMP	ZFIN:ZDB-MRPHLNO-070129-2	Zfish	PMID:18695040
Biological Process	GO:0048793	pronephros development	pkd2	IMP	ZFIN:ZDB-MRPHLNO-060630-4	Zfish	PMID:26839368
Biological Process	GO:0048793	pronephros development	pkd2	IGI	ZFIN:ZDB-MRPHLNO-060630-4,ZFIN:ZDB-MRPHLNO-100823-10	Zfish	PMID:21752935
Biological Process	GO:0048793	pronephros development	pkd2	IMP	ZFIN:ZDB-MRPHLNO-060630-4	Zfish	PMID:21752935
Biological Process	GO:0048793	pronephros development	pkd2	IMP	ZFIN:ZDB-MRPHLNO-070129-2	Zfish	PMID:16943304
Biological Process	GO:0072114	pronephros morphogenesis	pkd2	IMP	ZFIN:ZDB-MRPHLNO-060630-4	Zfish	PMID:28769124
Biological Process	GO:0072114	pronephros morphogenesis	pkd2	IMP	ZFIN:ZDB-MRPHLNO-060630-4	Zfish	PMID:20168298
Biological Process	GO:0051290	protein heterotetramerization	PKD2	IDA		Human	PMID:30093605
Biological Process	GO:0051289	protein homotetramerization	PKD2	IDA		Human	PMID:28092368
Biological Process	GO:0051262	protein tetramerization	PKD2	IDA		Human	PMID:29899465
Biological Process	GO:0065003	protein-containing complex assembly	pkd2	IPI	ZFIN:ZDB-GENE-030131-321,ZFIN:ZDB-GENE-030131-4637,ZFIN:ZDB-GENE-030131-6397	Zfish	PMID:31183407
Biological Process	GO:0072019	proximal convoluted tubule development	pkd2	IMP	ZFIN:ZDB-MRPHLNO-070129-4	Zfish	PMID:19127979
Biological Process	GO:0007259	receptor signaling pathway via JAK-STAT	Pkd2	EXP		Mouse	MGI:MGI:2178492|PMID:12007403
Biological Process	GO:0007259	receptor signaling pathway via JAK-STAT	Pkd2	IDA		Mouse	PMID:12007403
Biological Process	GO:0090279	regulation of calcium ion import	PKD2	IDA		Human	PMID:11854751
Biological Process	GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling	pkd2	IMP	ZFIN:ZDB-GENO-100715-11	Zfish	PMID:23376035
Biological Process	GO:0051726	regulation of cell cycle	Pkd2	IDA		Mouse	PMID:12007403
Biological Process	GO:0042127	regulation of cell population proliferation	PKD2	IMP		Human	PMID:15001556
Biological Process	GO:0032965	regulation of collagen biosynthetic process	pkd2	IMP	ZFIN:ZDB-MRPHLNO-070129-4	Zfish	PMID:20335443
Biological Process	GO:0051209	release of sequestered calcium ion into cytosol	PKD2	IDA		Human	PMID:11854751
Biological Process	GO:0051209	release of sequestered calcium ion into cytosol	PKD2	IMP		Human	PMID:19265036
Biological Process	GO:0051209	release of sequestered calcium ion into cytosol	Pkd2	IMP		Mouse	MGI:MGI:5315687|PMID:19265036
Biological Process	GO:0051209	release of sequestered calcium ion into cytosol	Pkd2	IMP	MGI:MGI:1860866	Mouse	PMID:17404231
Biological Process	GO:0061441	renal artery morphogenesis	PKD2	IEP		Human	PMID:11891195
Biological Process	GO:0061333	renal tubule morphogenesis	Pkd2	IMP		Mouse	MGI:MGI:4440396|PMID:20181743
Biological Process	GO:0035725	sodium ion transmembrane transport	PKD2	IDA		Human	PMID:11252306
Biological Process	GO:0035725	sodium ion transmembrane transport	PKD2	IMP		Human	PMID:27071085
Biological Process	GO:0021510	spinal cord development	PKD2	IEP		Human	PMID:11891195
Biological Process	GO:0003173	ventriculo bulbo valve development	pkd2	IMP	ZFIN:ZDB-GENO-200715-1	Zfish	PMID:31524599

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern