Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Pkn1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes PKN1
- Mouse genes Pkn1
- Rat genes Pkn1
- Zfish genes pkn1a,pkn1b
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pkn1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	PKN1	IDA		Human	PMID:18066052
Molecular Function	GO:0042393	histone binding	PKN1	IDA		Human	PMID:18066052
Molecular Function	GO:0042826	histone deacetylase binding	PKN1	IDA		Human	PMID:20188095
Molecular Function	GO:0035402	histone H3T11 kinase activity	PKN1	IDA		Human	PMID:18066052
Molecular Function	GO:0050681	nuclear androgen receptor binding	PKN1	IDA		Human	PMID:12514133
Molecular Function	GO:0050681	nuclear androgen receptor binding	PKN1	IDA		Human	PMID:18066052
Molecular Function	GO:0030374	nuclear receptor coactivator activity	PKN1	IDA		Human	PMID:12514133
Molecular Function	GO:0030374	nuclear receptor coactivator activity	PKN1	IMP		Human	PMID:18066052
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:P53778	Human	PMID:12761180
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:Q9NYL2-1	Human	PMID:12761180
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:Q15834	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:O60583-2	Human	PMID:16331689
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:D0ZVG2	Human	PMID:16611232
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:Q8WUI4	Human	PMID:20188095
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:Q9UKV0	Human	PMID:20188095
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:Q9UQL6	Human	PMID:20188095
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:Q9NSC5	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:O15344	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:P08670	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:P19012	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:Q01850	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:Q08379	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:Q15323	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:Q8IYX8-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:Q9NSC5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:Q9Y2D8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:A1JU68	Human	PMID:25513777
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:A1L190	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:A6NEM1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:A8MQ03	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:O00303	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:O75031	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:O75558	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:O76011	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:O76013-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:O76014	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:P07196	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:P08727	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:P08779	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:P14373	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:P15289	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:P28070	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:P54257	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:P78424	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:Q01850	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:Q08379	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:Q12933	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:Q13064	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:Q13077	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:Q15323	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:Q5JR59-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:Q5TA45	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:Q6PJH3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:Q6UY14-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:Q86T90	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:Q86XR8-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:Q8IW40	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:Q8IWV8-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:Q8N6Y0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:Q8ND90	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:Q8NHQ1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:Q8TD10	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:Q8TF47	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:Q8WWB3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:Q92764	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:Q96CS2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:Q96M89-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:Q96QF0-7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:Q96R06	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:Q9BV99	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:Q9BZW7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:Q9H2G9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:Q9H7B4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:Q9NRD5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:Q9NRI5-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:Q9NSC5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:Q9NZ72	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:Q9UGI0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:Q9UJV3-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:Q9UJW9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:Q9UKT9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:Q9ULX6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:P05067	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:P26641	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:Q06547-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:Q14457	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:Q8IV13	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:Q8N108-16	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:Q8N5Z5	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:Q8WTV1	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:Q8WU43	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:Q96MN9-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:Q9P0T4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PKN1	IPI	UniProtKB:Q9UNY5	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Pkn1	IPI	PR:Q9DCH6	Mouse	PMID:11054541
Molecular Function	GO:0004672	protein kinase activity	Pkn1	IMP		Mouse	PMID:12783890
Molecular Function	GO:0004672	protein kinase activity	Pkn1	IDA		Rat	PMID:8943281\|RGD:729504
Molecular Function	GO:0004697	protein kinase C activity	PKN1	EXP		Human	PMID:18066052
Molecular Function	GO:0005080	protein kinase C binding	PKN1	IPI	UniProtKB:P05771	Human	PMID:20228790
Molecular Function	GO:0004674	protein serine/threonine kinase activity	PKN1	IDA		Human	PMID:20188095
Molecular Function	GO:0031267	small GTPase binding	PKN1	IDA		Human	PMID:10619026
Molecular Function	GO:0031267	small GTPase binding	PKN1	IDA		Human	PMID:18006505
Molecular Function	GO:0031267	small GTPase binding	PKN1	IDA		Human	PMID:9478917
Cellular Component	GO:0032154	cleavage furrow	PKN1	IDA		Human	PMID:17332740
Cellular Component	GO:0005737	cytoplasm	PKN1	IDA		Human	PMID:12514133
Cellular Component	GO:0005737	cytoplasm	PKN1	IDA		Human	PMID:17332740
Cellular Component	GO:0005737	cytoplasm	Pkn1	IDA		Mouse	PMID:12783890
Cellular Component	GO:0031410	cytoplasmic vesicle	Pkn1	IDA		Mouse	PMID:12783890
Cellular Component	GO:0005768	endosome	PKN1	IDA		Human	PMID:9478917
Cellular Component	GO:0030496	midbody	PKN1	IDA		Human	PMID:17332740
Cellular Component	GO:0005634	nucleus	PKN1	IDA		Human	PMID:12514133
Biological Process	GO:0001783	B cell apoptotic process	Pkn1	IMP	MGI:MGI:5475202	Mouse	PMID:23223530
Biological Process	GO:0001782	B cell homeostasis	Pkn1	IMP	MGI:MGI:5475202	Mouse	PMID:23223530
Biological Process	GO:0010631	epithelial cell migration	PKN1	IMP		Human	PMID:21754995
Biological Process	GO:0006972	hyperosmotic response	Pkn1	IDA		Mouse	PMID:12783890
Biological Process	GO:0030889	negative regulation of B cell proliferation	Pkn1	IMP	MGI:MGI:5475202	Mouse	PMID:23223530
Biological Process	GO:0006469	negative regulation of protein kinase activity	Pkn1	IMP	MGI:MGI:5475202	Mouse	PMID:23223530
Biological Process	GO:0001933	negative regulation of protein phosphorylation	Pkn1	IMP	MGI:MGI:5475202	Mouse	PMID:23223530
Biological Process	GO:0043687	post-translational protein modification	PKN1	IDA		Human	PMID:18066052
Biological Process	GO:0006468	protein phosphorylation	PKN1	IDA		Human	PMID:17332740
Biological Process	GO:0006468	protein phosphorylation	Pkn1	IDA		Rat	PMID:8943281\|RGD:729504
Biological Process	GO:2000145	regulation of cell motility	PKN1	IMP		Human	PMID:21754995
Biological Process	GO:0002634	regulation of germinal center formation	Pkn1	IMP	MGI:MGI:5475202	Mouse	PMID:23223530
Biological Process	GO:0002637	regulation of immunoglobulin production	Pkn1	IMP	MGI:MGI:5475202	Mouse	PMID:23223530
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	PKN1	IDA		Human	PMID:12514133
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	PKN1	IMP		Human	PMID:18066052
Biological Process	GO:0003014	renal system process	Pkn1	IMP	MGI:MGI:5475202	Mouse	PMID:23223530
Biological Process	GO:0048536	spleen development	Pkn1	IMP	MGI:MGI:5475202	Mouse	PMID:23223530

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.