Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PKNOX2
  • Mouse genes Pknox2
  • Rat genes Pknox2
  • Zfish genes pknox2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pknox2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051015	actin filament binding	Pknox2	IDA		Mouse	PMID:15339927
Molecular Function	GO:0003785	actin monomer binding	Pknox2	IDA		Mouse	PMID:15339927
Molecular Function	GO:0003677	DNA binding	Pknox2	IDA		Mouse	PMID:12412021
Molecular Function	GO:0005515	protein binding	PKNOX2	IPI	UniProtKB:A0A024R8L2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKNOX2	IPI	UniProtKB:A0A1B0GWI1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKNOX2	IPI	UniProtKB:A5D8V6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKNOX2	IPI	UniProtKB:O14964	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKNOX2	IPI	UniProtKB:O60519	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKNOX2	IPI	UniProtKB:O75716	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKNOX2	IPI	UniProtKB:O95983-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKNOX2	IPI	UniProtKB:P46940	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKNOX2	IPI	UniProtKB:P48552	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKNOX2	IPI	UniProtKB:P53365	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKNOX2	IPI	UniProtKB:Q14192	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKNOX2	IPI	UniProtKB:Q6IPU0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKNOX2	IPI	UniProtKB:Q7Z3B4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKNOX2	IPI	UniProtKB:Q8IYX3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKNOX2	IPI	UniProtKB:Q8N6Y0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKNOX2	IPI	UniProtKB:Q8N715	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKNOX2	IPI	UniProtKB:Q8TAB5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKNOX2	IPI	UniProtKB:Q8TC76	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKNOX2	IPI	UniProtKB:Q8WZ74	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKNOX2	IPI	UniProtKB:Q96EZ8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKNOX2	IPI	UniProtKB:Q96GM5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKNOX2	IPI	UniProtKB:Q96RU7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKNOX2	IPI	UniProtKB:Q99816	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKNOX2	IPI	UniProtKB:Q9BVL2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKNOX2	IPI	UniProtKB:Q9BW61	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKNOX2	IPI	UniProtKB:Q9BYU1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKNOX2	IPI	UniProtKB:Q9H0I2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKNOX2	IPI	UniProtKB:Q9H0L4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKNOX2	IPI	UniProtKB:Q9H8K7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKNOX2	IPI	UniProtKB:Q9NRD5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKNOX2	IPI	UniProtKB:Q9P2B4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKNOX2	IPI	UniProtKB:Q99816	Human	PMID:35044719
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	Pknox2	IDA		Mouse	MGI:MGI:3653971|PMID:16847320
Molecular Function	GO:0043565	sequence-specific DNA binding	Pknox2	IDA		Mouse	PMID:16847320
Molecular Function	GO:0043565	sequence-specific DNA binding	Pknox2	IGI	MGI:MGI:97495	Mouse	PMID:17049510
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	PKNOX2	IDA		Human	PMID:28473536
Cellular Component	GO:0015629	actin cytoskeleton	Pknox2	IDA		Mouse	PMID:15339927
Cellular Component	GO:0005737	cytoplasm	Pknox2	IDA		Mouse	PMID:12412021
Cellular Component	GO:0045171	intercellular bridge	PKNOX2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0015630	microtubule cytoskeleton	Pknox2	IDA		Mouse	PMID:15339927
Cellular Component	GO:0005654	nucleoplasm	PKNOX2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Pknox2	IDA		Mouse	PMID:17049510
Cellular Component	GO:0005634	nucleus	Pknox2	IDA		Mouse	PMID:15339927
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	Pknox2	IGI	MGI:MGI:97495	Mouse	PMID:17049510

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern