Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PLA2G10
  • Mouse genes Pla2g10
  • Rat genes Pla2g10
  • Zfish genes pla2g10
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pla2g10

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity	PLA2G10	IDA		Human	PMID:16962371
Molecular Function	GO:0047498	calcium-dependent phospholipase A2 activity	PLA2G10	IDA		Human	PMID:12021277
Molecular Function	GO:0047498	calcium-dependent phospholipase A2 activity	PLA2G10	IDA		Human	PMID:12359733
Molecular Function	GO:0047498	calcium-dependent phospholipase A2 activity	PLA2G10	IDA		Human	PMID:16146426
Molecular Function	GO:0047498	calcium-dependent phospholipase A2 activity	PLA2G10	IDA		Human	PMID:16962371
Molecular Function	GO:0047498	calcium-dependent phospholipase A2 activity	Pla2g10	IDA		Mouse	MGI:MGI:2446974|PMID:12359733
Molecular Function	GO:0004623	phospholipase A2 activity	Pla2g10	IDA		Rat	PMID:15781456|RGD:1582547
Molecular Function	GO:0004620	phospholipase activity	Pla2g10	IMP		Mouse	MGI:MGI:5051938|PMID:20844270
Molecular Function	GO:0004620	phospholipase activity	Pla2g10	IMP	MGI:MGI:4412409	Mouse	PMID:26828067
Molecular Function	GO:0005515	protein binding	PLA2G10	IPI	UniProtKB:Q96HA8	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	PLA2G10	IPI	UniProtKB:A5D8V6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLA2G10	IPI	UniProtKB:A8MQ03	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLA2G10	IPI	UniProtKB:A8MV65-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLA2G10	IPI	UniProtKB:O14633	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLA2G10	IPI	UniProtKB:O14964	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLA2G10	IPI	UniProtKB:O43593	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLA2G10	IPI	UniProtKB:O43711	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLA2G10	IPI	UniProtKB:O60336	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLA2G10	IPI	UniProtKB:O75593	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLA2G10	IPI	UniProtKB:O75716	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLA2G10	IPI	UniProtKB:O95817	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLA2G10	IPI	UniProtKB:O95947	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLA2G10	IPI	UniProtKB:P09234	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLA2G10	IPI	UniProtKB:P21145	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLA2G10	IPI	UniProtKB:P21549	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLA2G10	IPI	UniProtKB:P29972	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLA2G10	IPI	UniProtKB:P31273	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLA2G10	IPI	UniProtKB:P32242	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLA2G10	IPI	UniProtKB:P54253	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLA2G10	IPI	UniProtKB:P78337	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLA2G10	IPI	UniProtKB:Q01974	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLA2G10	IPI	UniProtKB:Q02930-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLA2G10	IPI	UniProtKB:Q03989	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLA2G10	IPI	UniProtKB:Q0VD86	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLA2G10	IPI	UniProtKB:Q15319	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLA2G10	IPI	UniProtKB:Q5T749	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLA2G10	IPI	UniProtKB:Q5T751	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLA2G10	IPI	UniProtKB:Q5T7P2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLA2G10	IPI	UniProtKB:Q5TA79	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLA2G10	IPI	UniProtKB:Q5TA82	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLA2G10	IPI	UniProtKB:Q6P1W5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLA2G10	IPI	UniProtKB:Q6PEX3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLA2G10	IPI	UniProtKB:Q7Z5V6-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLA2G10	IPI	UniProtKB:Q86UR1-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLA2G10	IPI	UniProtKB:Q8IUC1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLA2G10	IPI	UniProtKB:Q8NEC5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLA2G10	IPI	UniProtKB:Q8WU58	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLA2G10	IPI	UniProtKB:Q92734	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLA2G10	IPI	UniProtKB:Q96HA8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLA2G10	IPI	UniProtKB:Q96HB5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLA2G10	IPI	UniProtKB:Q96K80	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLA2G10	IPI	UniProtKB:Q99932-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLA2G10	IPI	UniProtKB:Q9BWX5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLA2G10	IPI	UniProtKB:Q9BXY8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLA2G10	IPI	UniProtKB:Q9ULV5-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLA2G10	IPI	UniProtKB:Q9Y223-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLA2G10	IPI	UniProtKB:Q7Z699	Human	PMID:32814053
Cellular Component	GO:0001669	acrosomal vesicle	Pla2g10	IDA		Mouse	MGI:MGI:4459353|PMID:20424324
Cellular Component	GO:0005615	extracellular space	PLA2G10	IDA		Human	PMID:21805676
Biological Process	GO:0007411	axon guidance	PLA2G10	IDA		Human	PMID:15927955
Biological Process	GO:1990830	cellular response to leukemia inhibitory factor	Pla2g10	IEP		Mouse	PMID:20439489
Biological Process	GO:0042632	cholesterol homeostasis	Pla2g10	IMP		Mouse	MGI:MGI:5051938|PMID:20844270
Biological Process	GO:0051607	defense response to virus	PLA2G10	IDA		Human	PMID:16146426
Biological Process	GO:0043249	erythrocyte maturation	Pla2g10	IMP	MGI:MGI:4412409	Mouse	PMID:26828067
Biological Process	GO:0009566	fertilization	Pla2g10	IMP	MGI:MGI:4412409	Mouse	PMID:26828067
Biological Process	GO:0031069	hair follicle morphogenesis	Pla2g10	IMP		Mouse	MGI:MGI:4947921|PMID:21266583
Biological Process	GO:0036335	intestinal stem cell homeostasis	Pla2g10	IMP		Mouse	MGI:MGI:5818640|PMID:27292189
Biological Process	GO:0034374	low-density lipoprotein particle remodeling	PLA2G10	IDA		Human	PMID:12021277
Biological Process	GO:0051977	lysophospholipid transport	PLA2G10	IDA		Human	PMID:15927955
Biological Process	GO:0042116	macrophage activation	Pla2g10	IDA		Mouse	PMID:26828067
Biological Process	GO:0090370	negative regulation of cholesterol efflux	Pla2g10	IDA		Mouse	MGI:MGI:5051938|PMID:20844270
Biological Process	GO:1900016	negative regulation of cytokine production involved in inflammatory response	Pla2g10	IMP	MGI:MGI:4412409	Mouse	PMID:26828067
Biological Process	GO:0043433	negative regulation of DNA-binding transcription factor activity	PLA2G10	IDA		Human	PMID:20844270
Biological Process	GO:0043433	negative regulation of DNA-binding transcription factor activity	Pla2g10	IMP		Mouse	MGI:MGI:5051938|PMID:20844270
Biological Process	GO:0050728	negative regulation of inflammatory response	Pla2g10	IMP	MGI:MGI:4412409	Mouse	PMID:26828067
Biological Process	GO:0046473	phosphatidic acid metabolic process	PLA2G10	IDA		Human	PMID:12359733
Biological Process	GO:0046473	phosphatidic acid metabolic process	Pla2g10	IDA		Mouse	MGI:MGI:2446974|PMID:12359733
Biological Process	GO:0034638	phosphatidylcholine catabolic process	PLA2G10	IDA		Human	PMID:12021277
Biological Process	GO:0046470	phosphatidylcholine metabolic process	PLA2G10	IDA		Human	PMID:12359733
Biological Process	GO:0046470	phosphatidylcholine metabolic process	PLA2G10	IDA		Human	PMID:16146426
Biological Process	GO:0046470	phosphatidylcholine metabolic process	PLA2G10	IDA		Human	PMID:16962371
Biological Process	GO:0046470	phosphatidylcholine metabolic process	Pla2g10	IDA		Mouse	MGI:MGI:2446974|PMID:12359733
Biological Process	GO:0046337	phosphatidylethanolamine metabolic process	PLA2G10	IDA		Human	PMID:12359733
Biological Process	GO:0046337	phosphatidylethanolamine metabolic process	Pla2g10	IDA		Mouse	MGI:MGI:2446974|PMID:12359733
Biological Process	GO:0046337	phosphatidylethanolamine metabolic process	Pla2g10	IMP		Mouse	MGI:MGI:4947921|PMID:21266583
Biological Process	GO:0046471	phosphatidylglycerol metabolic process	PLA2G10	IDA		Human	PMID:12359733
Biological Process	GO:0046471	phosphatidylglycerol metabolic process	Pla2g10	IDA		Mouse	MGI:MGI:2446974|PMID:12359733
Biological Process	GO:0006658	phosphatidylserine metabolic process	PLA2G10	IDA		Human	PMID:12359733
Biological Process	GO:0006658	phosphatidylserine metabolic process	Pla2g10	IDA		Mouse	MGI:MGI:2446974|PMID:12359733
Biological Process	GO:0006644	phospholipid metabolic process	Pla2g10	IMP	MGI:MGI:4412409	Mouse	PMID:26828067
Biological Process	GO:0062234	platelet activating factor catabolic process	PLA2G10	IDA		Human	PMID:16962371
Biological Process	GO:2000344	positive regulation of acrosome reaction	Pla2g10	IMP		Mouse	MGI:MGI:4459353|PMID:20424324
Biological Process	GO:0090238	positive regulation of arachidonic acid secretion	Pla2g10	IDA		Mouse	MGI:MGI:5051938|PMID:20844270
Biological Process	GO:0010884	positive regulation of lipid storage	PLA2G10	IMP		Human	PMID:18511424
Biological Process	GO:0032308	positive regulation of prostaglandin secretion	PLA2G10	IMP		Human	PMID:18511424
Biological Process	GO:0051247	positive regulation of protein metabolic process	PLA2G10	IMP		Human	PMID:18511424
Biological Process	GO:0002532	production of molecular mediator involved in inflammatory response	Pla2g10	IDA		Mouse	PMID:26828067
Biological Process	GO:0002532	production of molecular mediator involved in inflammatory response	Pla2g10	IMP	MGI:MGI:4412409	Mouse	PMID:26828067
Biological Process	GO:0001516	prostaglandin biosynthetic process	Pla2g10	IDA		Mouse	MGI:MGI:5818640|PMID:27292189
Biological Process	GO:0043030	regulation of macrophage activation	PLA2G10	IMP		Human	PMID:18511424

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern