Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PLAA
  • Mouse genes Plaa
  • Rat genes Plaa
  • Zfish genes plaa
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Plaa

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016005	phospholipase A2 activator activity	Plaa	IDA		Mouse	PMID:2052621
Molecular Function	GO:0005515	protein binding	PLAA	IPI	UniProtKB:Q04323	Human	PMID:18775313
Molecular Function	GO:0005515	protein binding	PLAA	IPI	UniProtKB:Q76353	Human	PMID:22190034
Molecular Function	GO:0005515	protein binding	PLAA	IPI	UniProtKB:O00629	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PLAA	IPI	UniProtKB:Q04323	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PLAA	IPI	UniProtKB:V9HW80	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PLAA	IPI	UniProtKB:P55072,UniProtKB:Q5VVQ6,UniProtKB:Q9BZV1	Human	PMID:27753622
Molecular Function	GO:0005515	protein binding	PLAA	IPI	UniProtKB:P55072	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLAA	IPI	UniProtKB:Q04323-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLAA	IPI	UniProtKB:Q96D03	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Plaa	IPI	PR:Q01853	Mouse	PMID:19805280
Molecular Function	GO:0005515	protein binding	Plaa	IPI	PR:Q9Z2V5	Mouse	PMID:11689694
Cellular Component	GO:0005737	cytoplasm	PLAA	IDA		Human	PMID:27753622
Cellular Component	GO:0005737	cytoplasm	PLAA	IDA		Human	PMID:28007986
Cellular Component	GO:0005737	cytoplasm	Plaa	IDA		Mouse	MGI:MGI:5883825|PMID:28413018
Cellular Component	GO:0070062	extracellular exosome	PLAA	IDA		Human	PMID:17076679
Cellular Component	GO:0005634	nucleus	PLAA	IDA		Human	PMID:28007986
Cellular Component	GO:0005634	nucleus	Plaa	IDA		Mouse	MGI:MGI:5883825|PMID:28413018
Cellular Component	GO:0045202	synapse	Plaa	IDA		Mouse	MGI:MGI:5883825|PMID:28413018
Biological Process	GO:0071222	cellular response to lipopolysaccharide	PLAA	IMP		Human	PMID:28007986
Biological Process	GO:0006954	inflammatory response	Plaa	IDA		Mouse	PMID:2052621
Biological Process	GO:0016236	macroautophagy	PLAA	IMP		Human	PMID:27753622
Biological Process	GO:1900045	negative regulation of protein K63-linked ubiquitination	Plaa	IMP		Mouse	MGI:MGI:5883825|PMID:28413018
Biological Process	GO:1903861	positive regulation of dendrite extension	Plaa	IMP		Mouse	MGI:MGI:5883825|PMID:28413018
Biological Process	GO:2001224	positive regulation of neuron migration	Plaa	IMP		Mouse	MGI:MGI:5883825|PMID:28413018
Biological Process	GO:0032430	positive regulation of phospholipase A2 activity	PLAA	IMP		Human	PMID:28007986
Biological Process	GO:1903423	positive regulation of synaptic vesicle recycling	Plaa	IMP		Mouse	MGI:MGI:5883825|PMID:28413018
Biological Process	GO:0006693	prostaglandin metabolic process	Plaa	IMP		Mouse	MGI:MGI:6103030|PMID:28007986
Biological Process	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	Plaa	IMP		Mouse	MGI:MGI:5883825|PMID:28413018

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern