Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PLAC8
  • Mouse genes Plac8
  • Rat genes Plac8
  • Zfish genes plac8.1,plac8.2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Plac8

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Plac8	IDA		Mouse	PMID:21982742
Molecular Function	GO:0005515	protein binding	Plac8	IPI	PR:Q9JJ00	Mouse	PMID:16611984
Molecular Function	GO:0005515	protein binding	Plac8	IPI	PR:P28033	Mouse	PMID:21982742
Biological Process	GO:0050873	brown fat cell differentiation	Plac8	IMP	MGI:MGI:3834141	Mouse	PMID:21982742
Biological Process	GO:0042742	defense response to bacterium	Plac8	IMP	MGI:MGI:3834141	Mouse	PMID:17404296
Biological Process	GO:0043066	negative regulation of apoptotic process	Plac8	IDA		Mouse	PMID:12407160
Biological Process	GO:0043066	negative regulation of apoptotic process	Plac8	IGI	MGI:MGI:893575	Mouse	PMID:12407160
Biological Process	GO:0040015	negative regulation of multicellular organism growth	Plac8	IMP	MGI:MGI:3834141	Mouse	PMID:21982742
Biological Process	GO:0008284	positive regulation of cell population proliferation	Plac8	IDA		Mouse	PMID:16611984
Biological Process	GO:0120162	positive regulation of cold-induced thermogenesis	Plac8	IMP		Mouse	MGI:MGI:5302795|PMID:21982742
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Plac8	IDA		Mouse	PMID:21982742
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Plac8	IGI	MGI:MGI:88373	Mouse	PMID:21982742
Biological Process	GO:0009409	response to cold	Plac8	IMP	MGI:MGI:3834141	Mouse	PMID:21982742
Biological Process	GO:0006366	transcription by RNA polymerase II	Plac8	IGI	MGI:MGI:88373	Mouse	PMID:21982742
Biological Process	GO:0006366	transcription by RNA polymerase II	Plac8	IDA		Mouse	PMID:21982742

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern