Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PLAG1
  • Mouse genes Plag1
  • Rat genes Plag1
  • Zfish genes plag1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Plag1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	PLAG1	IDA		Human	PMID:10646861
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	PLAG1	IDA		Human	PMID:10646861
Cellular Component	GO:0005813	centrosome	PLAG1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	PLAG1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016607	nuclear speck	PLAG1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	PLAG1	IDA		Human	GO_REF:0000052
Biological Process	GO:0022612	gland morphogenesis	Plag1	IMP	MGI:MGI:3580633	Mouse	PMID:15606491
Biological Process	GO:0035264	multicellular organism growth	Plag1	IMP	MGI:MGI:3580633	Mouse	PMID:15606491
Biological Process	GO:0010629	negative regulation of gene expression	Plag1	IDA		Mouse	MGI:MGI:5285167|PMID:19808959
Biological Process	GO:0035265	organ growth	Plag1	IMP	MGI:MGI:3580633	Mouse	PMID:15606491
Biological Process	GO:0010628	positive regulation of gene expression	Plag1	IDA		Mouse	MGI:MGI:5285167|PMID:19808959
Biological Process	GO:0060252	positive regulation of glial cell proliferation	Plag1	IDA		Mouse	MGI:MGI:5285167|PMID:19808959
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	PLAG1	IDA		Human	PMID:10646861
Biological Process	GO:0060736	prostate gland growth	Plag1	IMP	MGI:MGI:3580633	Mouse	PMID:15606491

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern