Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PLAT
  • Mouse genes Plat
  • Rat genes Plat
  • Zfish genes plat
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Plat

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051219	phosphoprotein binding	PLAT	IPI	UniProtKB:A1YT10	Human	PMID:8186264
Molecular Function	GO:0051219	phosphoprotein binding	PLAT	IPI	UniProtKB:A3FJ56	Human	PMID:8186264
Molecular Function	GO:0051219	phosphoprotein binding	PLAT	IPI	UniProtKB:B2Z898	Human	PMID:8186264
Molecular Function	GO:0051219	phosphoprotein binding	PLAT	IPI	UniProtKB:E7E1P7	Human	PMID:8186264
Molecular Function	GO:0051219	phosphoprotein binding	PLAT	IPI	UniProtKB:E7E1P8	Human	PMID:8186264
Molecular Function	GO:0051219	phosphoprotein binding	PLAT	IPI	UniProtKB:E7E1Q1	Human	PMID:8186264
Molecular Function	GO:0051219	phosphoprotein binding	PLAT	IPI	UniProtKB:P02663	Human	PMID:8186264
Molecular Function	GO:0051219	phosphoprotein binding	PLAT	IPI	UniProtKB:P02668	Human	PMID:8186264
Molecular Function	GO:0051219	phosphoprotein binding	PLAT	IPI	UniProtKB:Q5ZET1	Human	PMID:8186264
Molecular Function	GO:0051219	phosphoprotein binding	PLAT	IPI	UniProtKB:Q5ZGI1	Human	PMID:8186264
Molecular Function	GO:0051219	phosphoprotein binding	PLAT	IPI	UniProtKB:Q705V4	Human	PMID:8186264
Molecular Function	GO:0005515	protein binding	PLAT	IPI	UniProtKB:P05154	Human	PMID:10340997
Molecular Function	GO:0005515	protein binding	PLAT	IPI	UniProtKB:P43025	Human	PMID:12694198
Molecular Function	GO:0005515	protein binding	PLAT	IPI	UniProtKB:Q04LZ5	Human	PMID:24196407
Molecular Function	GO:0005515	protein binding	PLAT	IPI	UniProtKB:P05121	Human	PMID:2503541
Molecular Function	GO:0004252	serine-type endopeptidase activity	PLAT	IDA		Human	PMID:1695900
Molecular Function	GO:0004252	serine-type endopeptidase activity	PLAT	IDA		Human	PMID:8508955
Molecular Function	GO:0004252	serine-type endopeptidase activity	Plat	IDA		Mouse	PMID:15372073
Molecular Function	GO:0005102	signaling receptor binding	PLAT	IPI	UniProtKB:Q05588	Human	PMID:8186264
Molecular Function	GO:0005102	signaling receptor binding	PLAT	IPI	UniProtKB:Q9TVA9	Human	PMID:8186264
Cellular Component	GO:0045177	apical part of cell	Plat	IDA		Mouse	PMID:15978259
Cellular Component	GO:0009986	cell surface	PLAT	IDA		Human	PMID:1632457
Cellular Component	GO:0005737	cytoplasm	PLAT	IDA		Human	PMID:1632457
Cellular Component	GO:0005737	cytoplasm	Plat	IDA		Mouse	PMID:15978259
Cellular Component	GO:0005737	cytoplasm	Plat	IDA		Rat	PMID:3891762|RGD:2311678
Cellular Component	GO:0070062	extracellular exosome	PLAT	HDA		Human	PMID:20458337
Cellular Component	GO:0005615	extracellular space	Plat	IDA		Mouse	PMID:15372073
Cellular Component	GO:0005615	extracellular space	Plat	IDA		Rat	PMID:10727258|RGD:6484219
Cellular Component	GO:0005615	extracellular space	Plat	IDA		Rat	PMID:3102470|RGD:2311679
Cellular Component	GO:0098978	glutamatergic synapse	Plat	IDA		Mouse	PMID:15486301
Cellular Component	GO:0098978	glutamatergic synapse	Plat	IMP		Mouse	PMID:15486301
Cellular Component	GO:0098978	glutamatergic synapse	Plat	IDA		Rat	PMID:16555239|RGD:13702316
Cellular Component	GO:0098978	glutamatergic synapse	Plat	IMP		Rat	PMID:16555239|RGD:13702316
Cellular Component	GO:0098992	neuronal dense core vesicle	Plat	IDA		Rat	PMID:21976424|RGD:13702320
Cellular Component	GO:0098992	neuronal dense core vesicle	Plat	IMP		Rat	PMID:21976424|RGD:13702320
Cellular Component	GO:0099544	perisynaptic space	Plat	IDA		Rat	PMID:16555239|RGD:13702316
Cellular Component	GO:0099544	perisynaptic space	Plat	IMP		Rat	PMID:16555239|RGD:13702316
Cellular Component	GO:0098794	postsynapse	Plat	IDA		Rat	PMID:15496678|RGD:1581924
Cellular Component	GO:0098794	postsynapse	Plat	IDA		Rat	PMID:16555239|RGD:13702316
Cellular Component	GO:0098794	postsynapse	Plat	IMP		Rat	PMID:16555239|RGD:13702316
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Plat	IDA		Mouse	PMID:15486301
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Plat	IMP		Mouse	PMID:15486301
Cellular Component	GO:0030141	secretory granule	Plat	IDA		Mouse	PMID:15978259
Cellular Component	GO:0097180	serine protease inhibitor complex	PLAT	IPI		Human	PMID:26324706
Cellular Component	GO:0045202	synapse	Plat	IDA		Mouse	MGI:MGI:3615067|PMID:15486301
Cellular Component	GO:0045202	synapse	Plat	IDA		Rat	PMID:15496678|RGD:1581924
Biological Process	GO:0071549	cellular response to dexamethasone stimulus	Plat	IEP		Rat	PMID:3137452|RGD:2311680
Biological Process	GO:0071372	cellular response to follicle-stimulating hormone stimulus	Plat	IEP		Rat	PMID:3102470|RGD:2311679
Biological Process	GO:0071373	cellular response to luteinizing hormone stimulus	Plat	IEP		Rat	PMID:3102470|RGD:2311679
Biological Process	GO:0045861	negative regulation of proteolysis	PLAT	IDA		Human	PMID:1695900
Biological Process	GO:0031639	plasminogen activation	PLAT	IDA		Human	PMID:12694198
Biological Process	GO:0031639	plasminogen activation	PLAT	IDA		Human	PMID:17849409
Biological Process	GO:0031639	plasminogen activation	PLAT	IDA		Human	PMID:24196407
Biological Process	GO:0031639	plasminogen activation	Plat	IDA		Rat	PMID:8343497|RGD:11537479
Biological Process	GO:0048008	platelet-derived growth factor receptor signaling pathway	Plat	IMP	MGI:MGI:1857288	Mouse	PMID:15372073
Biological Process	GO:0048008	platelet-derived growth factor receptor signaling pathway	Plat	IDA		Mouse	PMID:15372073
Biological Process	GO:0060279	positive regulation of ovulation	Plat	IMP		Rat	PMID:10727258|RGD:6484219
Biological Process	GO:0060468	prevention of polyspermy	Plat	IDA		Rat	PMID:1515147|RGD:42721992
Biological Process	GO:0006508	proteolysis	Plat	IDA		Mouse	PMID:15372073
Biological Process	GO:0048167	regulation of synaptic plasticity	Plat	IEP		Rat	PMID:12070304|RGD:628337
Biological Process	GO:0051591	response to cAMP	Plat	IEP		Rat	PMID:3017447|RGD:2311681
Biological Process	GO:0070542	response to fatty acid	Plat	IEP		Rat	PMID:14614217|RGD:2312394
Biological Process	GO:0001666	response to hypoxia	Plat	IMP		Mouse	PMID:17382917
Biological Process	GO:0014909	smooth muscle cell migration	Plat	IMP		Mouse	PMID:17382917
Biological Process	GO:0035249	synaptic transmission, glutamatergic	Plat	IMP		Rat	PMID:15496678|RGD:1581924
Biological Process	GO:0099183	trans-synaptic signaling by BDNF, modulating synaptic transmission	Plat	IMP		Mouse	PMID:15486301
Biological Process	GO:0099183	trans-synaptic signaling by BDNF, modulating synaptic transmission	Plat	IDA		Mouse	PMID:15486301
Biological Process	GO:0042060	wound healing	Plat	IEP		Rat	PMID:12524078|RGD:633572

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern