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Comparative GO Graph (mouse, human, rat, zebrafish)
Source
Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Plcg1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Plcg1
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0050429calcium-dependent phospholipase C activityPlcg1IDARatPMID:7531435|RGD:39458025
Molecular FunctionGO:0035254glutamate receptor bindingPlcg1IPIPR:Q01097MousePMID:16710293
Molecular FunctionGO:0005158insulin receptor bindingPlcg1IDARatPMID:14568990|RGD:1547862
Molecular FunctionGO:0005168neurotrophin TRKA receptor bindingPLCG1IPIUniProtKB:P04629HumanPMID:15488758
Molecular FunctionGO:0004435phosphatidylinositol phospholipase C activityPLCG1IDAHumanPMID:2550068
Molecular FunctionGO:0004435phosphatidylinositol phospholipase C activityPlcg1EXPMouseMGI:MGI:6218355|PMID:8615781
Molecular FunctionGO:0004435phosphatidylinositol phospholipase C activityPlcg1IDARatPMID:7531435|RGD:39458025
Molecular FunctionGO:0004629phospholipase C activityPLCG1IDAHumanPMID:20510673
Molecular FunctionGO:0004629phospholipase C activityPlcg1IMPMousePMID:28004780
Molecular FunctionGO:0051219phosphoprotein bindingPlcg1IPIRGD:2598RatPMID:8910399|RGD:1599952
Molecular FunctionGO:0005515protein bindingPLCG1IPIUniProtKB:O43561HumanPMID:10811803
Molecular FunctionGO:0005515protein bindingPLCG1IPIUniProtKB:Q13470HumanPMID:10873601
Molecular FunctionGO:0005515protein bindingPLCG1IPIUniProtKB:P06213HumanPMID:11796522
Molecular FunctionGO:0005515protein bindingPLCG1IPIUniProtKB:P09619HumanPMID:11896612
Molecular FunctionGO:0005515protein bindingPLCG1IPIUniProtKB:P09619HumanPMID:1396585
Molecular FunctionGO:0005515protein bindingPLCG1IPIUniProtKB:P00533HumanPMID:14568990
Molecular FunctionGO:0005515protein bindingPLCG1IPIUniProtKB:P06213HumanPMID:14568990
Molecular FunctionGO:0005515protein bindingPLCG1IPIUniProtKB:Q8WTV0-3HumanPMID:14570588
Molecular FunctionGO:0005515protein bindingPLCG1IPIUniProtKB:O43561HumanPMID:14722116
Molecular FunctionGO:0005515protein bindingPLCG1IPIUniProtKB:P09619HumanPMID:15641795
Molecular FunctionGO:0005515protein bindingPLCG1IPIUniProtKB:Q13094HumanPMID:15929943
Molecular FunctionGO:0005515protein bindingPLCG1IPIUniProtKB:P00533HumanPMID:16273093
Molecular FunctionGO:0005515protein bindingPLCG1IPIUniProtKB:P04626HumanPMID:16273093
Molecular FunctionGO:0005515protein bindingPLCG1IPIUniProtKB:P21860HumanPMID:16273093
Molecular FunctionGO:0005515protein bindingPLCG1IPIUniProtKB:P31749HumanPMID:16525023
Molecular FunctionGO:0005515protein bindingPLCG1IPIUniProtKB:P11362HumanPMID:1656221
Molecular FunctionGO:0005515protein bindingPLCG1IPIUniProtKB:P09327HumanPMID:16921170
Molecular FunctionGO:0005515protein bindingPLCG1IPIUniProtKB:O43561HumanPMID:16938345
Molecular FunctionGO:0005515protein bindingPLCG1IPIUniProtKB:P09327HumanPMID:17229814
Molecular FunctionGO:0005515protein bindingPLCG1IPIUniProtKB:O43150HumanPMID:17474147
Molecular FunctionGO:0005515protein bindingPLCG1IPIUniProtKB:P31994HumanPMID:17474147
Molecular FunctionGO:0005515protein bindingPLCG1IPIUniProtKB:P42684HumanPMID:17474147
Molecular FunctionGO:0005515protein bindingPLCG1IPIUniProtKB:Q07889HumanPMID:17474147
Molecular FunctionGO:0005515protein bindingPLCG1IPIUniProtKB:Q07890HumanPMID:17474147
Molecular FunctionGO:0005515protein bindingPLCG1IPIUniProtKB:Q15036HumanPMID:17474147
Molecular FunctionGO:0005515protein bindingPLCG1IPIUniProtKB:Q8TB24HumanPMID:17474147
Molecular FunctionGO:0005515protein bindingPLCG1IPIUniProtKB:Q92918HumanPMID:17474147
Molecular FunctionGO:0005515protein bindingPLCG1IPIUniProtKB:Q9BYB0HumanPMID:17474147
Molecular FunctionGO:0005515protein bindingPLCG1IPIUniProtKB:Q9H1R2HumanPMID:17474147
Molecular FunctionGO:0005515protein bindingPLCG1IPIUniProtKB:Q9ULH1HumanPMID:17474147
Molecular FunctionGO:0005515protein bindingPLCG1IPIUniProtKB:Q9UPX8HumanPMID:17474147
Molecular FunctionGO:0005515protein bindingPLCG1IPIUniProtKB:Q71V39HumanPMID:17936057
Molecular FunctionGO:0005515protein bindingPLCG1IPIUniProtKB:P63000HumanPMID:19264842
Molecular FunctionGO:0005515protein bindingPLCG1IPIUniProtKB:Q03135HumanPMID:20808760
Molecular FunctionGO:0005515protein bindingPLCG1IPIUniProtKB:P11362HumanPMID:20932831
Molecular FunctionGO:0005515protein bindingPLCG1IPIUniProtKB:P62993HumanPMID:21706016
Molecular FunctionGO:0005515protein bindingPLCG1IPIUniProtKB:Q13094HumanPMID:21725281
Molecular FunctionGO:0005515protein bindingPLCG1IPIUniProtKB:P09619HumanPMID:23063561
Molecular FunctionGO:0005515protein bindingPLCG1IPIUniProtKB:P11362HumanPMID:23063561
Molecular FunctionGO:0005515protein bindingPLCG1IPIUniProtKB:P09619HumanPMID:23397142
Molecular FunctionGO:0005515protein bindingPLCG1IPIUniProtKB:Q8N1K5-1HumanPMID:23460737
Molecular FunctionGO:0005515protein bindingPLCG1IPIUniProtKB:P21802-1HumanPMID:24440983
Molecular FunctionGO:0005515protein bindingPLCG1IPIUniProtKB:O14796HumanPMID:24642916
Molecular FunctionGO:0005515protein bindingPLCG1IPIUniProtKB:O43561HumanPMID:24642916
Molecular FunctionGO:0005515protein bindingPLCG1IPIUniProtKB:Q9BZW8HumanPMID:24642916
Molecular FunctionGO:0005515protein bindingPLCG1IPIUniProtKB:P08581HumanPMID:24728074
Molecular FunctionGO:0005515protein bindingPLCG1IPIUniProtKB:P10275HumanPMID:24728074
Molecular FunctionGO:0005515protein bindingPLCG1IPIUniProtKB:P10721HumanPMID:24728074
Molecular FunctionGO:0005515protein bindingPLCG1IPIUniProtKB:Q13480HumanPMID:24728074
Molecular FunctionGO:0005515protein bindingPLCG1IPIUniProtKB:P10721HumanPMID:25241761
Molecular FunctionGO:0005515protein bindingPLCG1IPIUniProtKB:P11362HumanPMID:25241761
Molecular FunctionGO:0005515protein bindingPLCG1IPIUniProtKB:Q07666HumanPMID:31413325
Molecular FunctionGO:0005515protein bindingPLCG1IPIUniProtKB:P04629HumanPMID:35384245
Molecular FunctionGO:0005515protein bindingPLCG1IPIUniProtKB:P09619HumanPMID:35384245
Molecular FunctionGO:0005515protein bindingPLCG1IPIUniProtKB:P11362HumanPMID:35384245
Molecular FunctionGO:0005515protein bindingPLCG1IPIUniProtKB:P10721HumanPMID:7537096
Molecular FunctionGO:0005515protein bindingPLCG1IPIUniProtKB:Q07666HumanPMID:7537265
Molecular FunctionGO:0005515protein bindingPLCG1IPIUniProtKB:P00533HumanPMID:7693694
Molecular FunctionGO:0005515protein bindingPLCG1IPIUniProtKB:P00533HumanPMID:7993895
Molecular FunctionGO:0005515protein bindingPLCG1IPIUniProtKB:P11362HumanPMID:8321198
Molecular FunctionGO:0005515protein bindingPLCG1IPIUniProtKB:P04629HumanPMID:8384556
Molecular FunctionGO:0005515protein bindingPLCG1IPIUniProtKB:P20273HumanPMID:8627166
Molecular FunctionGO:0005515protein bindingPLCG1IPIUniProtKB:P43405HumanPMID:8657103
Molecular FunctionGO:0005515protein bindingPLCG1IPIUniProtKB:P42768HumanPMID:8892607
Molecular FunctionGO:0005515protein bindingPLCG1IPIUniProtKB:P00533HumanPMID:9020117
Molecular FunctionGO:0005515protein bindingPLCG1IPIUniProtKB:P62993HumanPMID:9020117
Molecular FunctionGO:0005515protein bindingPLCG1IPIUniProtKB:Q07889HumanPMID:9020117
Molecular FunctionGO:0005515protein bindingPLCG1IPIUniProtKB:Q07666HumanPMID:9045636
Molecular FunctionGO:0005515protein bindingPLCG1IPIUniProtKB:O43561HumanPMID:9489702
Molecular FunctionGO:0005515protein bindingPLCG1IPIUniProtKB:P06213HumanPMID:9593725
Molecular FunctionGO:0005515protein bindingPLCG1IPIUniProtKB:Q8WV28HumanPMID:9697839
Molecular FunctionGO:0005515protein bindingPlcg1IPIUniProtKB:P14753|UniProtKB:Q60631MouseMGI:MGI:3689794|PMID:15953601
Molecular FunctionGO:0005515protein bindingPlcg1IPIUniProtKB:P48356MouseMGI:MGI:3629374|PMID:16698021
Molecular FunctionGO:0005515protein bindingPlcg1IPIUniProtKB:O54957|UniProtKB:Q60631MouseMGI:MGI:5432321|PMID:22561606
Molecular FunctionGO:0005515protein bindingPlcg1IPIUniProtKB:Q62468MouseMGI:MGI:5009178|PMID:12937273
Molecular FunctionGO:0005515protein bindingPlcg1IPIUniProtKB:O54957MouseMGI:MGI:5568870|PMID:24584089
Molecular FunctionGO:0005515protein bindingPlcg1IPIUniProtKB:Q8BGW0MouseMGI:MGI:4352756|PMID:19597499
Molecular FunctionGO:0005515protein bindingPlcg1IPIUniProtKB:O54957MouseMGI:MGI:5003385|PMID:21487392
Molecular FunctionGO:0005515protein bindingPlcg1IPIPR:Q60787MousePMID:15599401
Molecular FunctionGO:0005515protein bindingPlcg1IPIPR:000049793MousePMID:27609517
Molecular FunctionGO:0005515protein bindingPlcg1IPIUniprotKB:Q60787MousePMID:27609517
Molecular FunctionGO:0005515protein bindingPlcg1IPIUniProtKB:Q60749RatPMID:10077576|RGD:727209
Molecular FunctionGO:0005515protein bindingPlcg1IPIUniProtKB:Q9WU01RatPMID:10077576|RGD:727209
Molecular FunctionGO:0005515protein bindingPlcg1IPIRGD:1310949RatPMID:10913276|RGD:1581107
Molecular FunctionGO:0005515protein bindingPlcg1IPIRGD:69276RatPMID:11779129|RGD:70605
Molecular FunctionGO:0005515protein bindingPlcg1IPIRGD:621604RatPMID:12507498|RGD:734467
Molecular FunctionGO:0005515protein bindingPlcg1IPIRGD:2201RatPMID:15607753|RGD:1625041
Molecular FunctionGO:0005515protein bindingPlcg1IPIUniProtKB:Q13507RatPMID:15744307|RGD:8554100
Molecular FunctionGO:0005515protein bindingPlcg1IPIRGD:621458RatPMID:16819285|RGD:1599284
Molecular FunctionGO:0005515protein bindingPlcg1IPIUniProtKB:P18031RatPMID:17128263|RGD:8554302
Molecular FunctionGO:0005515protein bindingPlcg1IPIUniProtKB:Q62120RatPMID:17128263|RGD:8554302
Molecular FunctionGO:0005515protein bindingPlcg1IPIUniProtKB:Q08881RatPMID:18443296|RGD:21201265
Molecular FunctionGO:0005515protein bindingPlcg1IPIUniProtKB:P11362RatPMID:19665973|RGD:8554792
Molecular FunctionGO:0005515protein bindingPlcg1IPIUniProtKB:Q04589RatPMID:19665973|RGD:8554792
Molecular FunctionGO:0005515protein bindingPlcg1IPIRGD:3214|RGD:619787RatPMID:22764246|RGD:10044012
Molecular FunctionGO:0005515protein bindingPlcg1IPIUniProtKB:Q08881RatPMID:31585087|RGD:21201274
Molecular FunctionGO:0019901protein kinase bindingPLCG1IPIUniProtKB:O15530HumanPMID:22454520
Molecular FunctionGO:0030971receptor tyrosine kinase bindingPlcg1IPIUniProtKB:P15209MouseMGI:MGI:3772008|PMID:12367511
Cellular ComponentGO:0042995cell projectionPLCG1IDAHumanPMID:22454520
Cellular ComponentGO:0005911cell-cell junctionPlcg1IDAMousePMID:23793062
Cellular ComponentGO:0030136clathrin-coated vesiclePlcg1IDARatPMID:11779129|RGD:70605
Cellular ComponentGO:0008180COP9 signalosomePLCG1IDAHumanPMID:22561606
Cellular ComponentGO:0005737cytoplasmPLCG1IDAHumanPMID:15702972
Cellular ComponentGO:0005829cytosolPLCG1IDAHumanGO_REF:0000052
Cellular ComponentGO:0005829cytosolPLCG1IDAHumanPMID:2550068
Cellular ComponentGO:0098978glutamatergic synapsePlcg1IDAMousePMID:28138157
Cellular ComponentGO:0098978glutamatergic synapsePlcg1IMPMousePMID:28138157
Cellular ComponentGO:0030027lamellipodiumPLCG1IDAHumanPMID:17229814
Cellular ComponentGO:0016020membranePlcg1IDARatPMID:7812955|RGD:151356942
Cellular ComponentGO:0043005neuron projectionPlcg1IDARatPMID:16819285|RGD:1599284
Cellular ComponentGO:0005886plasma membranePLCG1IDAHumanPMID:20510673
Cellular ComponentGO:0005886plasma membranePLCG1IDAHumanPMID:22454520
Cellular ComponentGO:0005886plasma membranePLCG1IDAHumanPMID:2550068
Cellular ComponentGO:0001726rufflePLCG1IDAHumanPMID:17229814
Cellular ComponentGO:0032587ruffle membranePLCG1IDAHumanPMID:11331309
Cellular ComponentGO:0098685Schaffer collateral - CA1 synapsePlcg1IDAMousePMID:28138157
Cellular ComponentGO:0098685Schaffer collateral - CA1 synapsePlcg1IMPMousePMID:28138157
Biological ProcessGO:0001525angiogenesisplcg1IMPZFIN:ZDB-GENO-090603-13ZfishPMID:19269286
Biological ProcessGO:0001525angiogenesisplcg1IMPZFIN:ZDB-GENO-090730-7ZfishPMID:19332767
Biological ProcessGO:0001525angiogenesisplcg1IMPZFIN:ZDB-MRPHLNO-130313-1ZfishPMID:27789478
Biological ProcessGO:0001525angiogenesisplcg1IMPZFIN:ZDB-GENO-090603-21ZfishPMID:19269286
Biological ProcessGO:0001525angiogenesisplcg1IMPZFIN:ZDB-GENO-090603-17ZfishPMID:19269286
Biological ProcessGO:0001525angiogenesisplcg1IMPZFIN:ZDB-GENO-130409-13ZfishPMID:23220656
Biological ProcessGO:0048844artery morphogenesisplcg1IMPZFIN:ZDB-MRPHLNO-051214-1ZfishPMID:19815777
Biological ProcessGO:0006816calcium ion transportPlcg1IMPRatPMID:12437926|RGD:729542
Biological ProcessGO:0019722calcium-mediated signalingPLCG1IMPHumanPMID:22454520
Biological ProcessGO:0016477cell migrationPLCG1IMPHumanPMID:22454520
Biological ProcessGO:0071364cellular response to epidermal growth factor stimulusPLCG1IDAHumanPMID:17229814
Biological ProcessGO:0071364cellular response to epidermal growth factor stimulusPLCG1IMPHumanPMID:22454520
Biological ProcessGO:0007173epidermal growth factor receptor signaling pathwayPLCG1IMPHumanPMID:22454520
Biological ProcessGO:0007173epidermal growth factor receptor signaling pathwayPlcg1IDARatPMID:7531435|RGD:39458025
Biological ProcessGO:0031101fin regenerationplcg1IMPZFIN:ZDB-GENO-030502-1ZfishPMID:16565716
Biological ProcessGO:0030851granulocyte differentiationplcg1IMPZFIN:ZDB-GENO-130409-13ZfishPMID:23220656
Biological ProcessGO:0030851granulocyte differentiationplcg1IMPZFIN:ZDB-MRPHLNO-130313-1ZfishPMID:23220656
Biological ProcessGO:0060218hematopoietic stem cell differentiationplcg1IMPZFIN:ZDB-GENO-090730-7ZfishPMID:19332767
Biological ProcessGO:0060218hematopoietic stem cell differentiationplcg1IMPZFIN:ZDB-MRPHLNO-051214-1ZfishPMID:19332767
Biological ProcessGO:0001701in utero embryonic developmentPlcg1IMPMGI:MGI:2388142MousePMID:11744703
Biological ProcessGO:0032959inositol trisphosphate biosynthetic processPlcg1IMPRatPMID:16973916|RGD:2299886
Biological ProcessGO:0032957inositol trisphosphate metabolic processPlcg1IDARatPMID:7812955|RGD:151356942
Biological ProcessGO:0050804modulation of chemical synaptic transmissionPlcg1IDAMousePMID:28138157
Biological ProcessGO:0050804modulation of chemical synaptic transmissionPlcg1IMPMousePMID:28138157
Biological ProcessGO:0031161phosphatidylinositol catabolic processPlcg1IDARatPMID:7812955|RGD:151356942
Biological ProcessGO:0046488phosphatidylinositol metabolic processPlcg1IDARatPMID:7531435|RGD:39458025
Biological ProcessGO:0045766positive regulation of angiogenesisPLCG1IDAHumanPMID:20011604
Biological ProcessGO:0043536positive regulation of blood vessel endothelial cell migrationPLCG1IDAHumanPMID:20011604
Biological ProcessGO:2000353positive regulation of endothelial cell apoptotic processPLCG1IMPHumanPMID:27464494
Biological ProcessGO:0010634positive regulation of epithelial cell migrationPLCG1IMPHumanPMID:17229814
Biological ProcessGO:0010634positive regulation of epithelial cell migrationPlcg1IMPRatPMID:16973916|RGD:2299886
Biological ProcessGO:0051281positive regulation of release of sequestered calcium ion into cytosolPLCG1IMPHumanPMID:22454520
Biological ProcessGO:1905564positive regulation of vascular endothelial cell proliferationPLCG1IMPHumanPMID:27464494
Biological ProcessGO:0009306protein secretionPlcg1IMPRatPMID:12507498|RGD:734467
Biological ProcessGO:0035477regulation of angioblast cell migration involved in selective angioblast sproutingplcg1IMPZFIN:ZDB-MRPHLNO-051214-1ZfishPMID:19815777
Biological ProcessGO:0008016regulation of heart contractionplcg1IMPZFIN:ZDB-MRPHLNO-050906-6ZfishPMID:15998812
Biological ProcessGO:0008016regulation of heart contractionplcg1IMPZFIN:ZDB-GENO-980202-311ZfishPMID:15998812
Biological ProcessGO:1901339regulation of store-operated calcium channel activityPlcg1IMPRatPMID:17432954|RGD:2299884
Biological ProcessGO:1904643response to curcuminPlcg1IDARatPMID:7812955|RGD:151356942
Biological ProcessGO:0009629response to gravityPlcg1IEPRatPMID:17404041|RGD:2299885
Biological ProcessGO:0042542response to hydrogen peroxidePlcg1IEPRatPMID:17982259|RGD:2299876
Biological ProcessGO:0043278response to morphinePlcg1IEPRatPMID:17524370|RGD:2299883
Biological ProcessGO:0010243response to organonitrogen compoundPlcg1IEPRatPMID:16973916|RGD:2299886
Biological ProcessGO:0010243response to organonitrogen compoundPlcg1IDARatPMID:7812955|RGD:151356942
Biological ProcessGO:0050852T cell receptor signaling pathwayPlcg1IDAMousePMID:15728238
Biological ProcessGO:0001570vasculogenesisplcg1IMPZFIN:ZDB-GENO-980202-311ZfishPMID:15998812
Biological ProcessGO:0001570vasculogenesisplcg1IMPZFIN:ZDB-GENO-090730-7ZfishPMID:19332767
Biological ProcessGO:0001570vasculogenesisplcg1IMPZFIN:ZDB-MRPHLNO-050906-6ZfishPMID:15998812
Biological ProcessGO:0001570vasculogenesisplcg1IMPZFIN:ZDB-GENO-090608-6ZfishPMID:19269286
Biological ProcessGO:0001570vasculogenesisplcg1IMPZFIN:ZDB-GENO-030502-1ZfishPMID:16565716

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IEP Inferred from expression pattern
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction
  HTP Inferred from High Throughput Experiment
  HDA Inferred from High Throughput Direct Assay
  HMP Inferred from High Throughput Mutant Phenotype
  HGI Inferred from High Throughput Genetic Interaction
  HEP Inferred from High Throughput Expression Pattern

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory