Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PLD1
  • Mouse genes Pld1
  • Rat genes Pld1
  • Zfish genes pld1a,pld1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pld1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004630	phospholipase D activity	Pld1	IDA		Rat	PMID:12431982|RGD:729596
Molecular Function	GO:0004630	phospholipase D activity	pld1a	IDA		Zfish	PMID:19389349
Molecular Function	GO:0005515	protein binding	PLD1	IPI	UniProtKB:P23528	Human	PMID:17853892
Molecular Function	GO:0005515	protein binding	PLD1	IPI	UniProtKB:Q15382	Human	PMID:18550814
Molecular Function	GO:0005515	protein binding	PLD1	IPI	UniProtKB:O15287	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PLD1	IPI	UniProtKB:P05067	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PLD1	IPI	UniProtKB:P15923-3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PLD1	IPI	UniProtKB:Q08AE8	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PLD1	IPI	UniProtKB:Q0VD86	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PLD1	IPI	UniProtKB:Q12888	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PLD1	IPI	UniProtKB:Q6NXG1	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PLD1	IPI	UniProtKB:Q6XD76	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PLD1	IPI	UniProtKB:Q6ZQX7-4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PLD1	IPI	UniProtKB:Q9H7C4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Pld1	IPI	UniProtKB:P49769	Mouse	MGI:MGI:6092896|PMID:16449386
Molecular Function	GO:0005515	protein binding	Pld1	IPI	RGD:3395	Rat	PMID:12431982|RGD:729596
Cellular Component	GO:0016324	apical plasma membrane	PLD1	IDA		Human	PMID:22797597
Cellular Component	GO:0098981	cholinergic synapse	PLD1	IDA		Human	PMID:11752468
Cellular Component	GO:0098981	cholinergic synapse	PLD1	IMP		Human	PMID:11752468
Cellular Component	GO:0030139	endocytic vesicle	PLD1	IDA		Human	PMID:22797597
Cellular Component	GO:0005768	endosome	PLD1	IDA		Human	PMID:14718562
Cellular Component	GO:0005794	Golgi apparatus	PLD1	IDA		Human	PMID:14718562
Cellular Component	GO:0031985	Golgi cisterna	Pld1	IDA		Rat	PMID:12429836|RGD:2299914
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	Pld1	IDA		Rat	PMID:10824686|RGD:2299919
Cellular Component	GO:0030027	lamellipodium	Pld1	IDA		Rat	PMID:18344600|RGD:2299899
Cellular Component	GO:0005765	lysosomal membrane	PLD1	HDA		Human	PMID:17897319
Cellular Component	GO:0016020	membrane	PLD1	HDA		Human	PMID:19946888
Cellular Component	GO:0045202	synapse	Pld1	IDA		Rat	PMID:11752468|RGD:70245
Cellular Component	GO:0031982	vesicle	Pld1	IDA		Rat	PMID:18344600|RGD:2299899
Biological Process	GO:0001525	angiogenesis	pld1a	IMP	ZFIN:ZDB-MRPHLNO-090528-1,ZFIN:ZDB-MRPHLNO-090528-2	Zfish	PMID:19389349
Biological Process	GO:0001525	angiogenesis	pld1a	IMP	ZFIN:ZDB-MRPHLNO-090528-1	Zfish	PMID:19389349
Biological Process	GO:0001525	angiogenesis	pld1a	IMP	ZFIN:ZDB-MRPHLNO-090528-2	Zfish	PMID:19389349
Biological Process	GO:0050830	defense response to Gram-positive bacterium	Pld1	IMP		Mouse	PMID:11544318
Biological Process	GO:0006654	phosphatidic acid biosynthetic process	Pld1	IMP		Rat	PMID:18519738|RGD:8554572
Biological Process	GO:0008654	phospholipid biosynthetic process	Pld1	IMP		Rat	PMID:18519738|RGD:8554572
Biological Process	GO:0009395	phospholipid catabolic process	Pld1	IMP		Rat	PMID:16459925|RGD:2299904
Biological Process	GO:0030335	positive regulation of cell migration	Pld1	IMP		Rat	PMID:18344600|RGD:2299899
Biological Process	GO:0045727	positive regulation of translation	PLD1	IMP		Human	PMID:25361009
Biological Process	GO:0032534	regulation of microvillus assembly	PLD1	IMP		Human	PMID:22797597
Biological Process	GO:0098693	regulation of synaptic vesicle cycle	PLD1	IDA		Human	PMID:11752468
Biological Process	GO:0098693	regulation of synaptic vesicle cycle	PLD1	IMP		Human	PMID:11752468
Biological Process	GO:0043434	response to peptide hormone	Pld1	IMP		Rat	PMID:16459925|RGD:2299904

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern