Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PLD6
  • Mouse genes Pld6
  • Rat genes Pld6
  • Zfish genes pld6
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pld6

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0035755	cardiolipin hydrolase activity	PLD6	IDA		Human	PMID:17028579
Molecular Function	GO:0035755	cardiolipin hydrolase activity	PLD6	IDA		Human	PMID:21397848
Molecular Function	GO:0042802	identical protein binding	Pld6	IPI	UniProtKB:Q5SWZ9-1	Mouse	MGI:MGI:5444769|PMID:23064227
Molecular Function	GO:0005515	protein binding	PLD6	IPI	UniProtKB:Q7L4E1	Human	PMID:26711011
Molecular Function	GO:0005515	protein binding	PLD6	IPI	UniProtKB:Q8NAN2	Human	PMID:26711011
Molecular Function	GO:0005515	protein binding	PLD6	IPI	UniProtKB:Q14410	Human	PMID:28852571
Molecular Function	GO:0005515	protein binding	Pld6	IPI	UniProtKB:Q99MV5	Mouse	MGI:MGI:5638960|PMID:25762440
Molecular Function	GO:0005515	protein binding	Pld6	IPI	UniProtKB:Q9WU65	Mouse	MGI:MGI:6355765|PMID:28852571
Molecular Function	GO:0042803	protein homodimerization activity	PLD6	IDA		Human	PMID:17028579
Cellular Component	GO:0005741	mitochondrial outer membrane	PLD6	IDA		Human	PMID:17028579
Cellular Component	GO:0005741	mitochondrial outer membrane	PLD6	IDA		Human	PMID:21397848
Cellular Component	GO:0005741	mitochondrial outer membrane	Pld6	IDA		Mouse	MGI:MGI:4943610|PMID:21397847
Biological Process	GO:0043046	DNA methylation involved in gamete generation	Pld6	IMP		Mouse	MGI:MGI:4943610|PMID:21397847
Biological Process	GO:0051321	meiotic cell cycle	Pld6	IMP		Mouse	MGI:MGI:4943610|PMID:21397847
Biological Process	GO:0051321	meiotic cell cycle	Pld6	IMP		Mouse	MGI:MGI:4943609|PMID:21397848
Biological Process	GO:0008053	mitochondrial fusion	PLD6	IMP		Human	PMID:17028579
Biological Process	GO:0030719	P granule organization	Pld6	IMP		Mouse	MGI:MGI:4943609|PMID:21397848
Biological Process	GO:0034587	piRNA processing	Pld6	IMP		Mouse	MGI:MGI:4943609|PMID:21397848
Biological Process	GO:0034587	piRNA processing	Pld6	IMP		Mouse	MGI:MGI:4943610|PMID:21397847
Biological Process	GO:0010636	positive regulation of mitochondrial fusion	PLD6	IDA		Human	PMID:24599962
Biological Process	GO:0007286	spermatid development	Pld6	IMP		Mouse	MGI:MGI:4943609|PMID:21397848
Biological Process	GO:0007286	spermatid development	Pld6	IMP		Mouse	MGI:MGI:4943610|PMID:21397847

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern