Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PLEKHA2
  • Mouse genes Plekha2
  • Rat genes Plekha2
  • Zfish genes plekha2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Plekha2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001968	fibronectin binding	PLEKHA2	IMP		Human	PMID:19786618
Molecular Function	GO:0043236	laminin binding	PLEKHA2	IMP		Human	PMID:19786618
Molecular Function	GO:0030165	PDZ domain binding	Plekha2	IPI	UniProtKB:Q12923	Mouse	MGI:MGI:4441132|PMID:14516276
Molecular Function	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	PLEKHA2	IDA		Human	PMID:11001876
Molecular Function	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	Plekha2	IDA		Mouse	PMID:11001876
Molecular Function	GO:0005515	protein binding	PLEKHA2	IPI	UniProtKB:P46939	Human	PMID:19786618
Molecular Function	GO:0005515	protein binding	PLEKHA2	IPI	UniProtKB:Q13425	Human	PMID:19786618
Molecular Function	GO:0005515	protein binding	PLEKHA2	IPI	UniProtKB:O14908	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLEKHA2	IPI	UniProtKB:O75031	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLEKHA2	IPI	UniProtKB:P36406	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLEKHA2	IPI	UniProtKB:Q08379	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLEKHA2	IPI	UniProtKB:Q15700	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLEKHA2	IPI	UniProtKB:Q5TD97	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLEKHA2	IPI	UniProtKB:Q63ZY3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLEKHA2	IPI	UniProtKB:Q8TBB1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLEKHA2	IPI	UniProtKB:Q8TC57	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLEKHA2	IPI	UniProtKB:Q8TF64	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLEKHA2	IPI	UniProtKB:Q8TF65	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLEKHA2	IPI	UniProtKB:Q92796	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLEKHA2	IPI	UniProtKB:Q96N21	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLEKHA2	IPI	UniProtKB:Q9H6Z9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLEKHA2	IPI	UniProtKB:Q9NSN8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLEKHA2	IPI	UniProtKB:Q9Y2V7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Plekha2	IPI	UniProtKB:O75970	Mouse	MGI:MGI:5508287|PMID:11802782
Cellular Component	GO:0005737	cytoplasm	PLEKHA2	IDA		Human	PMID:19786618
Cellular Component	GO:0016020	membrane	PLEKHA2	IDA		Human	PMID:19786618
Cellular Component	GO:0032991	protein-containing complex	PLEKHA2	IDA		Human	PMID:19786618
Biological Process	GO:0001954	positive regulation of cell-matrix adhesion	PLEKHA2	IMP		Human	PMID:19786618

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern